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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for DYNC1I2 |
 Gene summary |
| Gene information | Gene symbol | DYNC1I2 | Gene ID | 1781 |
| Gene name | dynein cytoplasmic 1 intermediate chain 2 | |
| Synonyms | DIC74|DNCI2|IC2|NEDMIBA | |
| Cytomap | 2q31.1 | |
| Type of gene | protein-coding | |
| Description | cytoplasmic dynein 1 intermediate chain 2DH IC-2dynein intermediate chain 2, cytosolicdynein, cytoplasmic, intermediate polypeptide 2testis tissue sperm-binding protein Li 66n | |
| Modification date | 20200315 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for DYNC1I2 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000077380
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PCC | UP | ENST00000479806.1 | DYNC1I2-223:retained_intron:DYNC1I2 | 3.500490e+01 | 1.634571e+00 | 1.261848e-06 | 3.061112e-04 |
| PCC | UP | ENST00000456808.5 | DYNC1I2-219:protein_coding:DYNC1I2 | 8.645199e+00 | 1.182270e+00 | 3.448744e-04 | 1.302564e-02 |
| HCC | UP | ENST00000479806.1 | DYNC1I2-223:retained_intron:DYNC1I2 | 1.680112e+01 | 1.299936e+00 | 1.230913e-04 | 8.311657e-03 |
| CB | DOWN | ENST00000479806.1 | DYNC1I2-223:retained_intron:DYNC1I2 | 3.700587e+02 | -1.138881e+00 | 2.091818e-06 | 2.806621e-05 |
| CB | UP | ENST00000438879.5 | DYNC1I2-215:protein_coding:DYNC1I2 | 8.915930e+00 | 2.233959e+00 | 2.856257e-06 | 3.658275e-05 |
| CB | UP | ENST00000411953.5 | DYNC1I2-208:protein_coding:DYNC1I2 | 1.041778e+01 | 1.268688e+00 | 9.383970e-05 | 7.018218e-04 |
| TC | DOWN | ENST00000479806.1 | DYNC1I2-223:retained_intron:DYNC1I2 | 2.901425e+02 | -2.070424e+00 | 2.278212e-12 | 7.461468e-10 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for DYNC1I2 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_107104 | chr2 | 171690147:171690263:171692777:171692894:171707233:171707377 | 171692777:171692894 |
| exon_skip_116414 | chr2 | 171692777:171692894:171707233:171707377:171715328:171715350 | 171707233:171707377 |
| exon_skip_122272 | chr2 | 171692777:171692894:171707287:171707377:171715328:171715350 | 171707287:171707377 |
| exon_skip_131233 | chr2 | 171692781:171692894:171707233:171707377:171715328:171715443 | 171707233:171707377 |
| exon_skip_139143 | chr2 | 171692777:171692894:171707287:171707377:171712767:171712779 | 171707287:171707377 |
| exon_skip_139764 | chr2 | 171692777:171692894:171707233:171707377:171712767:171712779 | 171707233:171707377 |
| exon_skip_149560 | chr2 | 171692777:171692894:171707233:171707377:171715328:171715443 | 171707233:171707377 |
| exon_skip_174503 | chr2 | 171725919:171726081:171726194:171726293:171726791:171726852 | 171726194:171726293 |
| exon_skip_17669 | chr2 | 171690147:171690263:171692777:171692894:171707287:171707377 | 171692777:171692894 |
| exon_skip_178062 | chr2 | 171692777:171692894:171707287:171707377:171715328:171715443 | 171707287:171707377 |
| exon_skip_180734 | chr2 | 171707287:171707377:171712767:171712826:171715328:171715350 | 171712767:171712826 |
| exon_skip_181210 | chr2 | 171690147:171690263:171692777:171692894:171715328:171715350 | 171692777:171692894 |
| exon_skip_21687 | chr2 | 171692781:171692894:171715328:171715443:171725618:171725650 | 171715328:171715443 |
| exon_skip_250924 | chr2 | 171727821:171727967:171728305:171728418:171728717:171728768 | 171728305:171728418 |
| exon_skip_260222 | chr2 | 171692781:171692894:171706547:171706564:171707287:171707377 | 171706547:171706564 |
| exon_skip_271271 | chr2 | 171727821:171727967:171728305:171728418:171728717:171728850 | 171728305:171728418 |
| exon_skip_35903 | chr2 | 171692777:171692894:171706547:171706564:171707287:171707377 | 171706547:171706564 |
| exon_skip_44799 | chr2 | 171692777:171692894:171715328:171715443:171725618:171725650 | 171715328:171715443 |
| exon_skip_52926 | chr2 | 171715390:171715443:171725618:171725713:171725919:171725946 | 171725618:171725713 |
| exon_skip_75347 | chr2 | 171692781:171692894:171707287:171707377:171715328:171715443 | 171707287:171707377 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_180734 | MSBB_PG | 1.632450e-01 | 2.998276e-01 | -1.365826e-01 | 2.111467e-08 |
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Open reading frame (ORF) annotation in the exon skipping event for DYNC1I2 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000397119 | 171726194 | 171726293 | Frame-shift |
| ENST00000409773 | 171726194 | 171726293 | Frame-shift |
| ENST00000397119 | 171706547 | 171706564 | In-frame |
| ENST00000409773 | 171706547 | 171706564 | In-frame |
| ENST00000397119 | 171712767 | 171712826 | In-frame |
| ENST00000409773 | 171712767 | 171712826 | In-frame |
| ENST00000397119 | 171725618 | 171725713 | In-frame |
| ENST00000409773 | 171725618 | 171725713 | In-frame |
| ENST00000397119 | 171728305 | 171728418 | In-frame |
| ENST00000409773 | 171728305 | 171728418 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000397119 | 171706547 | 171706564 | In-frame |
| ENST00000409773 | 171706547 | 171706564 | In-frame |
| ENST00000397119 | 171712767 | 171712826 | In-frame |
| ENST00000409773 | 171712767 | 171712826 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000397119 | 171726194 | 171726293 | Frame-shift |
| ENST00000409773 | 171726194 | 171726293 | Frame-shift |
| ENST00000397119 | 171706547 | 171706564 | In-frame |
| ENST00000409773 | 171706547 | 171706564 | In-frame |
| ENST00000397119 | 171712767 | 171712826 | In-frame |
| ENST00000409773 | 171712767 | 171712826 | In-frame |
| ENST00000397119 | 171725618 | 171725713 | In-frame |
| ENST00000409773 | 171725618 | 171725713 | In-frame |
| ENST00000397119 | 171728305 | 171728418 | In-frame |
| ENST00000409773 | 171728305 | 171728418 | In-frame |
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Infer the effects of exon skipping event on protein functional features for DYNC1I2 |
p-ENSG00000077380_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000397119 | 2621 | 638 | 171712767 | 171712826 | 504 | 562 | 112 | 131 |
| ENST00000409773 | 2600 | 638 | 171712767 | 171712826 | 476 | 534 | 112 | 131 |
| ENST00000397119 | 2621 | 638 | 171725618 | 171725713 | 680 | 774 | 171 | 202 |
| ENST00000409773 | 2600 | 638 | 171725618 | 171725713 | 652 | 746 | 171 | 202 |
| ENST00000397119 | 2621 | 638 | 171728305 | 171728418 | 1312 | 1424 | 381 | 419 |
| ENST00000409773 | 2600 | 638 | 171728305 | 171728418 | 1284 | 1396 | 381 | 419 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000397119 | 2621 | 638 | 171712767 | 171712826 | 504 | 562 | 112 | 131 |
| ENST00000409773 | 2600 | 638 | 171712767 | 171712826 | 476 | 534 | 112 | 131 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000397119 | 2621 | 638 | 171712767 | 171712826 | 504 | 562 | 112 | 131 |
| ENST00000409773 | 2600 | 638 | 171712767 | 171712826 | 476 | 534 | 112 | 131 |
| ENST00000397119 | 2621 | 638 | 171725618 | 171725713 | 680 | 774 | 171 | 202 |
| ENST00000409773 | 2600 | 638 | 171725618 | 171725713 | 652 | 746 | 171 | 202 |
| ENST00000397119 | 2621 | 638 | 171728305 | 171728418 | 1312 | 1424 | 381 | 419 |
| ENST00000409773 | 2600 | 638 | 171728305 | 171728418 | 1284 | 1396 | 381 | 419 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q13409 | 112 | 131 | 113 | 132 | Alternative sequence | ID=VSP_001337;Note=In isoform 2C%2C isoform 2F and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:17974005,ECO:00 |
| Q13409 | 112 | 131 | 113 | 132 | Alternative sequence | ID=VSP_001337;Note=In isoform 2C%2C isoform 2F and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:17974005,ECO:00 |
| Q13409 | 112 | 131 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 112 | 131 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 171 | 202 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 171 | 202 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 381 | 419 | 384 | 389 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 384 | 389 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 398 | 402 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 398 | 402 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 405 | 410 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 405 | 410 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 419 | 423 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 419 | 423 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 381 | 419 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 381 | 419 | 379 | 420 | Repeat | Note=WD 3 |
| Q13409 | 381 | 419 | 379 | 420 | Repeat | Note=WD 3 |
| Q13409 | 381 | 419 | 393 | 395 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 393 | 395 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q13409 | 112 | 131 | 113 | 132 | Alternative sequence | ID=VSP_001337;Note=In isoform 2C%2C isoform 2F and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:17974005,ECO:00 |
| Q13409 | 112 | 131 | 113 | 132 | Alternative sequence | ID=VSP_001337;Note=In isoform 2C%2C isoform 2F and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:17974005,ECO:00 |
| Q13409 | 112 | 131 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 112 | 131 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q13409 | 112 | 131 | 113 | 132 | Alternative sequence | ID=VSP_001337;Note=In isoform 2C%2C isoform 2F and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:17974005,ECO:00 |
| Q13409 | 112 | 131 | 113 | 132 | Alternative sequence | ID=VSP_001337;Note=In isoform 2C%2C isoform 2F and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:17974005,ECO:00 |
| Q13409 | 112 | 131 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 112 | 131 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 171 | 202 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 171 | 202 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 381 | 419 | 384 | 389 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 384 | 389 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 398 | 402 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 398 | 402 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 405 | 410 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 405 | 410 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 419 | 423 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 419 | 423 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 381 | 419 | 2 | 638 | Chain | ID=PRO_0000114655;Note=Cytoplasmic dynein 1 intermediate chain 2 |
| Q13409 | 381 | 419 | 379 | 420 | Repeat | Note=WD 3 |
| Q13409 | 381 | 419 | 379 | 420 | Repeat | Note=WD 3 |
| Q13409 | 381 | 419 | 393 | 395 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
| Q13409 | 381 | 419 | 393 | 395 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:6F1U |
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3'-UTR located exon skipping events that lost miRNA binding sites in DYNC1I2 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for DYNC1I2 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for DYNC1I2 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
| ADstage | MSBB | PG | exon_skip_180734 | -3.955287e-01 | 3.080000e-09 | chr2 | + | 171707287 | 171707377 | 171712767 | 171712826 | 171715328 | 171715350 |
| ADstage | ROSMAP | PCC | exon_skip_180734 | -3.097637e-01 | 3.660000e-06 | chr2 | + | 171707287 | 171707377 | 171712767 | 171712826 | 171715328 | 171715350 |
| CDR | MSBB | PG | exon_skip_180734 | -4.951389e-01 | 2.510000e-14 | chr2 | + | 171707287 | 171707377 | 171712767 | 171712826 | 171715328 | 171715350 |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for DYNC1I2 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
| TC | exon_skip_180734 | rs7602864 | chr2:171631067 | 1.166173e-05 | 2.813114e-03 |
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Correlation with RNA binding proteins (RBPs) for DYNC1I2 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | FXR2 | exon_skip_180734 | 4.316077e-01 | 1.346060e-08 |
| FL | RALYL | exon_skip_35903 | 4.654708e-01 | 4.861040e-12 |
| FL | MBNL1 | exon_skip_180734 | 4.378342e-01 | 1.115120e-10 |
| FL | FXR2 | exon_skip_180734 | 4.814610e-01 | 6.949091e-13 |
| HCC | RBM6 | exon_skip_35903 | -6.549764e-01 | 7.789979e-35 |
| HCC | U2AF2 | exon_skip_35903 | -4.820995e-01 | 2.698212e-17 |
| HCC | TIA1 | exon_skip_35903 | -5.415857e-01 | 3.294074e-22 |
| HCC | TRNAU1AP | exon_skip_35903 | -5.675244e-01 | 1.127511e-24 |
| HCC | FUBP1 | exon_skip_35903 | -5.248485e-01 | 9.974764e-21 |
| HCC | RALY | exon_skip_35903 | -7.003341e-01 | 1.444979e-41 |
| HCC | PTBP1 | exon_skip_35903 | -7.196840e-01 | 7.691679e-45 |
| HCC | RBMS3 | exon_skip_180734 | -5.261714e-01 | 7.670003e-21 |
| IFG | RBM24 | exon_skip_35903 | 5.121865e-01 | 5.329457e-03 |
| IFG | RALYL | exon_skip_35903 | 5.006272e-01 | 6.661240e-03 |
| IFG | PTBP1 | exon_skip_35903 | -4.144021e-01 | 2.834464e-02 |
| IFG | FXR2 | exon_skip_180734 | 4.997263e-01 | 6.775902e-03 |
| PCC | RALYL | exon_skip_260222 | 4.045766e-01 | 7.128686e-10 |
| PCC | PTBP1 | exon_skip_260222 | -5.600485e-01 | 3.771531e-19 |
| PG | RBM24 | exon_skip_35903 | 4.755127e-01 | 8.598832e-13 |
| PG | RALYL | exon_skip_35903 | 5.770635e-01 | 2.499721e-19 |
| PG | CELF1 | exon_skip_35903 | 4.274159e-01 | 2.238053e-10 |
| PG | FXR2 | exon_skip_180734 | 5.083677e-01 | 3.906258e-15 |
| STG | RBM24 | exon_skip_35903 | 4.668095e-01 | 2.725390e-06 |
| STG | RALYL | exon_skip_35903 | 5.850161e-01 | 9.135171e-10 |
| STG | PTBP1 | exon_skip_35903 | -4.423854e-01 | 1.008953e-05 |
| TC | ELAVL1 | exon_skip_35903 | 4.437641e-01 | 4.168583e-09 |
| TC | RBM24 | exon_skip_35903 | 7.934547e-01 | 6.738731e-36 |
| TC | RALYL | exon_skip_35903 | 8.715558e-01 | 8.979254e-51 |
| TC | PTBP3 | exon_skip_35903 | 5.354427e-01 | 2.987148e-13 |
| TC | CELF1 | exon_skip_35903 | 6.023041e-01 | 3.604549e-17 |
| TC | FXR2 | exon_skip_180734 | 5.119721e-01 | 4.533465e-12 |
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RelatedDrugs for DYNC1I2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DYNC1I2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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