|
||||||
|
 | |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| 3'-UTR located exon skipping events lost miRNA binding sites |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| |
| |
|
Gene summary for KANSL1L |
 Gene summary |
| Gene information | Gene symbol | KANSL1L | Gene ID | 151050 |
| Gene name | KAT8 regulatory NSL complex subunit 1 like | |
| Synonyms | C2orf67|MSL1v2 | |
| Cytomap | 2q34 | |
| Type of gene | protein-coding | |
| Description | KAT8 regulatory NSL complex subunit 1-like proteinmale-specific lethal 1 homolog | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
Gene structures and expression levels for KANSL1L |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
ENSG00000144445
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | UP | ENST00000418791.5 | KANSL1L-203:protein_coding:KANSL1L | 6.000028e+01 | 1.191068e+00 | 1.313249e-08 | 3.796634e-07 |
| TC | UP | ENST00000418791.5 | KANSL1L-203:protein_coding:KANSL1L | 4.816826e+01 | 1.192811e+00 | 1.402408e-05 | 3.379045e-04 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
 |
Top |
Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for KANSL1L |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
 |
| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_126736 | chr2 | 210029803:210029918:210031421:210031546:210040420:210040527 | 210031421:210031546 |
| exon_skip_14160 | chr2 | 210129031:210129172:210153495:210154611:210171149:210171327 | 210153495:210154611 |
| exon_skip_142731 | chr2 | 210028845:210028969:210029803:210029918:210040420:210040527 | 210029803:210029918 |
| exon_skip_178765 | chr2 | 210075552:210075756:210098086:210098207:210104104:210104195 | 210098086:210098207 |
| exon_skip_211298 | chr2 | 210025104:210025216:210026380:210026402:210027296:210027350 | 210026380:210026402 |
| exon_skip_264012 | chr2 | 210098086:210098207:210104104:210104301:210129031:210129172 | 210104104:210104301 |
| exon_skip_277148 | chr2 | 210031421:210031546:210040420:210040527:210043939:210044104 | 210040420:210040527 |
| exon_skip_292383 | chr2 | 210043939:210044104:210075552:210075756:210098086:210098207 | 210075552:210075756 |
| exon_skip_29683 | chr2 | 210028845:210028969:210029803:210029918:210031421:210031546 | 210029803:210029918 |
| exon_skip_46678 | chr2 | 210025104:210025216:210027296:210027350:210028845:210028969 | 210027296:210027350 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
 |