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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for SHROOM1 |
 Gene summary |
| Gene information | Gene symbol | SHROOM1 | Gene ID | 134549 |
| Gene name | shroom family member 1 | |
| Synonyms | APXL2 | |
| Cytomap | 5q31.1 | |
| Type of gene | protein-coding | |
| Description | protein Shroom1apical protein 2 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for SHROOM1 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000164403
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
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| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PG | UP | ENST00000440118.1 | SHROOM1-204:protein_coding:SHROOM1 | 4.227244e+00 | 1.239282e+00 | 6.005650e-05 | 1.884575e-03 |
| PG | UP | ENST00000488072.1 | SHROOM1-205:lncRNA:SHROOM1 | 6.665957e+00 | 8.091230e-01 | 1.369834e-03 | 1.825921e-02 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for SHROOM1 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_105421 | chr5 | 132825169:132826182:132826277:132826587:132827461:132827576 | 132826277:132826587 |
| exon_skip_12394 | chr5 | 132823850:132824419:132824615:132824821:132825018:132825073 | 132824615:132824821 |
| exon_skip_202911 | chr5 | 132824402:132824419:132824615:132824821:132825018:132825073 | 132824615:132824821 |
| exon_skip_21485 | chr5 | 132825169:132826182:132826277:132826587:132827461:132827607 | 132826277:132826587 |
| exon_skip_246581 | chr5 | 132824365:132824419:132824615:132824821:132825018:132825073 | 132824615:132824821 |
| exon_skip_247834 | chr5 | 132826143:132826182:132826277:132826587:132827461:132827607 | 132826277:132826587 |
| exon_skip_256640 | chr5 | 132823623:132823764:132823850:132824419:132824615:132824821 | 132823850:132824419 |
| exon_skip_276286 | chr5 | 132823623:132823764:132823850:132824419:132825018:132825073 | 132823850:132824419 |
| exon_skip_283043 | chr5 | 132824281:132824419:132825018:132825073:132825163:132826140 | 132825018:132825073 |
| exon_skip_43983 | chr5 | 132824615:132824821:132825018:132825073:132825163:132826140 | 132825018:132825073 |
| exon_skip_86305 | chr5 | 132825169:132826182:132826277:132826587:132827461:132827588 | 132826277:132826587 |
| exon_skip_90960 | chr5 | 132824281:132824419:132824615:132824821:132825018:132825073 | 132824615:132824821 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for SHROOM1 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000378679 | 132826277 | 132826587 | 3UTR-3UTR |
| ENST00000378679 | 132825018 | 132825073 | Frame-shift |
| ENST00000617339 | 132825018 | 132825073 | Frame-shift |
| ENST00000378679 | 132823850 | 132824419 | In-frame |
| ENST00000617339 | 132823850 | 132824419 | In-frame |
| ENST00000378679 | 132824615 | 132824821 | In-frame |
| ENST00000617339 | 132824615 | 132824821 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000378679 | 132824615 | 132824821 | In-frame |
| ENST00000617339 | 132824615 | 132824821 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000378679 | 132826277 | 132826587 | 3UTR-3UTR |
| ENST00000378679 | 132825018 | 132825073 | Frame-shift |
| ENST00000617339 | 132825018 | 132825073 | Frame-shift |
| ENST00000378679 | 132823850 | 132824419 | In-frame |
| ENST00000617339 | 132823850 | 132824419 | In-frame |
| ENST00000378679 | 132824615 | 132824821 | In-frame |
| ENST00000617339 | 132824615 | 132824821 | In-frame |
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Infer the effects of exon skipping event on protein functional features for SHROOM1 |
p-ENSG00000164403_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000378679 | 4036 | 852 | 132824615 | 132824821 | 1840 | 2045 | 345 | 413 |
| ENST00000617339 | 3655 | 852 | 132824615 | 132824821 | 1479 | 1684 | 345 | 413 |
| ENST00000378679 | 4036 | 852 | 132823850 | 132824419 | 2047 | 2615 | 414 | 603 |
| ENST00000617339 | 3655 | 852 | 132823850 | 132824419 | 1686 | 2254 | 414 | 603 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000378679 | 4036 | 852 | 132824615 | 132824821 | 1840 | 2045 | 345 | 413 |
| ENST00000617339 | 3655 | 852 | 132824615 | 132824821 | 1479 | 1684 | 345 | 413 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000378679 | 4036 | 852 | 132824615 | 132824821 | 1840 | 2045 | 345 | 413 |
| ENST00000617339 | 3655 | 852 | 132824615 | 132824821 | 1479 | 1684 | 345 | 413 |
| ENST00000378679 | 4036 | 852 | 132823850 | 132824419 | 2047 | 2615 | 414 | 603 |
| ENST00000617339 | 3655 | 852 | 132823850 | 132824419 | 1686 | 2254 | 414 | 603 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q2M3G4 | 345 | 413 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 345 | 413 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 414 | 603 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 414 | 603 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 414 | 603 | 543 | 825 | Domain | Note=ASD2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00638 |
| Q2M3G4 | 414 | 603 | 543 | 825 | Domain | Note=ASD2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00638 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q2M3G4 | 345 | 413 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 345 | 413 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q2M3G4 | 345 | 413 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 345 | 413 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 414 | 603 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 414 | 603 | 1 | 852 | Chain | ID=PRO_0000286061;Note=Protein Shroom1 |
| Q2M3G4 | 414 | 603 | 543 | 825 | Domain | Note=ASD2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00638 |
| Q2M3G4 | 414 | 603 | 543 | 825 | Domain | Note=ASD2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00638 |
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3'-UTR located exon skipping events that lost miRNA binding sites in SHROOM1 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6734-3p | chr5:132826413-132826420 | 8mer-1a | chr5:132826396-132826420 | 151.00 | -22.26 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4257 | chr5:132826385-132826392 | 8mer-1a | chr5:132826385-132826407 | 149.00 | -32.25 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6745 | chr5:132826535-132826542 | 8mer-1a | chr5:132826523-132826542 | 165.00 | -25.78 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4487 | chr5:132826428-132826435 | 8mer-1a | chr5:132826423-132826445 | 167.00 | -29.50 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-8052 | chr5:132826371-132826378 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-7106-3p | chr5:132826378-132826385 | 8mer-1a | chr5:132826364-132826388 | 154.00 | -30.24 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6763-5p | chr5:132826521-132826528 | 8mer-1a | chr5:132826521-132826542 | 155.00 | -32.29 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-1266-5p | chr5:132826476-132826483 | 8mer-1a | chr5:132826472-132826492 | 158.00 | -25.08 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4516 | chr5:132826568-132826575 | 8mer-1a | chr5:132826558-132826575 | 150.00 | -19.47 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4717-3p | chr5:132826573-132826580 | 8mer-1a | chr5:132826559-132826580 | 146.00 | -16.48 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4518 | chr5:132826476-132826483 | 8mer-1a | chr5:132826472-132826492 | 158.00 | -25.08 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4522 | chr5:132826330-132826337 | 8mer-1a | chr5:132826327-132826345 | 151.00 | -28.17 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-5010-5p | chr5:132826314-132826321 | 8mer-1a | chr5:132826300-132826321 | 164.00 | -25.97 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6780a-3p | chr5:132826356-132826363 | 8mer-1a | chr5:132826335-132826364 | 151.00 | -27.23 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4525 | chr5:132826314-132826321 | 8mer-1a | chr5:132826300-132826321 | 164.00 | -25.97 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-637 | chr5:132826316-132826323 | 8mer-1a | chr5:132826300-132826323 | 158.00 | -25.72 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6791-5p | chr5:132826375-132826382 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4434 | chr5:132826568-132826575 | 8mer-1a | chr5:132826558-132826575 | 150.00 | -19.47 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-5703 | chr5:132826568-132826575 | 8mer-1a | chr5:132826558-132826575 | 150.00 | -19.47 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-10401-5p | chr5:132826457-132826464 | 8mer-1a | chr5:132826444-132826464 | 155.00 | -23.38 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6814-5p | chr5:132826338-132826345 | 8mer-1a | chr5:132826327-132826345 | 151.00 | -28.17 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-3199 | chr5:132826371-132826378 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4763-3p | chr5:132826438-132826445 | 8mer-1a | chr5:132826423-132826445 | 167.00 | -29.50 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6825-5p | chr5:132826520-132826527 | 8mer-1a | chr5:132826514-132826534 | 156.00 | -25.53 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-3150a-3p | chr5:132826521-132826528 | 8mer-1a | chr5:132826521-132826542 | 155.00 | -32.29 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-3151-3p | chr5:132826343-132826350 | 8mer-1a | chr5:132826335-132826364 | 151.00 | -27.23 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-1207-5p | chr5:132826438-132826445 | 8mer-1a | chr5:132826423-132826445 | 167.00 | -29.50 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-147a | chr5:132826458-132826465 | 8mer-1a | chr5:132826450-132826472 | 149.00 | -15.57 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4292 | chr5:132826375-132826382 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| Mayo | ENST00000378679 | 132826277 | 132826587 | hsa-miR-363-5p | chr5:132826535-132826542 | 8mer-1a | chr5:132826523-132826542 | 165.00 | -25.78 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6734-3p | chr5:132826413-132826420 | 8mer-1a | chr5:132826396-132826420 | 151.00 | -22.26 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4257 | chr5:132826385-132826392 | 8mer-1a | chr5:132826385-132826407 | 149.00 | -32.25 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6745 | chr5:132826535-132826542 | 8mer-1a | chr5:132826523-132826542 | 165.00 | -25.78 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4487 | chr5:132826428-132826435 | 8mer-1a | chr5:132826423-132826445 | 167.00 | -29.50 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-8052 | chr5:132826371-132826378 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-7106-3p | chr5:132826378-132826385 | 8mer-1a | chr5:132826364-132826388 | 154.00 | -30.24 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6763-5p | chr5:132826521-132826528 | 8mer-1a | chr5:132826521-132826542 | 155.00 | -32.29 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-1266-5p | chr5:132826476-132826483 | 8mer-1a | chr5:132826472-132826492 | 158.00 | -25.08 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4516 | chr5:132826568-132826575 | 8mer-1a | chr5:132826558-132826575 | 150.00 | -19.47 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4717-3p | chr5:132826573-132826580 | 8mer-1a | chr5:132826559-132826580 | 146.00 | -16.48 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4518 | chr5:132826476-132826483 | 8mer-1a | chr5:132826472-132826492 | 158.00 | -25.08 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4522 | chr5:132826330-132826337 | 8mer-1a | chr5:132826327-132826345 | 151.00 | -28.17 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-5010-5p | chr5:132826314-132826321 | 8mer-1a | chr5:132826300-132826321 | 164.00 | -25.97 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6780a-3p | chr5:132826356-132826363 | 8mer-1a | chr5:132826335-132826364 | 151.00 | -27.23 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4525 | chr5:132826314-132826321 | 8mer-1a | chr5:132826300-132826321 | 164.00 | -25.97 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-637 | chr5:132826316-132826323 | 8mer-1a | chr5:132826300-132826323 | 158.00 | -25.72 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6791-5p | chr5:132826375-132826382 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4434 | chr5:132826568-132826575 | 8mer-1a | chr5:132826558-132826575 | 150.00 | -19.47 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-5703 | chr5:132826568-132826575 | 8mer-1a | chr5:132826558-132826575 | 150.00 | -19.47 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-10401-5p | chr5:132826457-132826464 | 8mer-1a | chr5:132826444-132826464 | 155.00 | -23.38 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6814-5p | chr5:132826338-132826345 | 8mer-1a | chr5:132826327-132826345 | 151.00 | -28.17 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-3199 | chr5:132826371-132826378 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4763-3p | chr5:132826438-132826445 | 8mer-1a | chr5:132826423-132826445 | 167.00 | -29.50 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-6825-5p | chr5:132826520-132826527 | 8mer-1a | chr5:132826514-132826534 | 156.00 | -25.53 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-3150a-3p | chr5:132826521-132826528 | 8mer-1a | chr5:132826521-132826542 | 155.00 | -32.29 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-3151-3p | chr5:132826343-132826350 | 8mer-1a | chr5:132826335-132826364 | 151.00 | -27.23 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-1207-5p | chr5:132826438-132826445 | 8mer-1a | chr5:132826423-132826445 | 167.00 | -29.50 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-147a | chr5:132826458-132826465 | 8mer-1a | chr5:132826450-132826472 | 149.00 | -15.57 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-4292 | chr5:132826375-132826382 | 8mer-1a | chr5:132826361-132826382 | 163.00 | -30.11 |
| ROSMAP | ENST00000378679 | 132826277 | 132826587 | hsa-miR-363-5p | chr5:132826535-132826542 | 8mer-1a | chr5:132826523-132826542 | 165.00 | -25.78 |
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SNVs in the skipped exons for SHROOM1 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for SHROOM1 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for SHROOM1 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for SHROOM1 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | ZNF638 | exon_skip_202911 | 5.905379e-01 | 2.553116e-16 |
| CB | RBM6 | exon_skip_202911 | 5.300146e-01 | 6.753056e-13 |
| CB | TRA2A | exon_skip_202911 | 5.473444e-01 | 8.302795e-14 |
| CB | FUBP1 | exon_skip_202911 | 4.079094e-01 | 9.452900e-08 |
| CB | TARDBP | exon_skip_271597 | -4.778248e-01 | 3.692733e-10 |
| CB | PCBP1 | exon_skip_271597 | -4.372944e-01 | 1.422884e-08 |
| CB | PCBP2 | exon_skip_271597 | -4.007272e-01 | 2.606863e-07 |
| CB | HNRNPC | exon_skip_271597 | -4.808624e-01 | 2.753888e-10 |
| CB | HNRNPL | exon_skip_271597 | -4.063697e-01 | 1.701805e-07 |
| TC | RBM4 | exon_skip_269518 | -4.358152e-01 | 9.049485e-07 |
| TC | RBM4 | exon_skip_96912 | -4.366105e-01 | 8.599955e-07 |
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RelatedDrugs for SHROOM1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SHROOM1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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