|
Open reading frame (ORF) annotation in the exon skipping event | |
3'-UTR located exon skipping events lost miRNA binding sites | |
Splicing Quantitative Trait Loci (sQTLs) in the skipped exons | |
Gene summary for CLTA |
Gene summary |
Gene information | Gene symbol | CLTA | Gene ID | 1211 |
Gene name | clathrin light chain A | |
Synonyms | LCA | |
Cytomap | 9p13.3 | |
Type of gene | protein-coding | |
Description | clathrin light chain Aclathrin, light polypeptide (Lca) | |
Modification date | 20200313 | |
UniProtAcc | ||
Context |
Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Gene | GO ID | GO term | PubMed ID |
Top |
Gene structures and expression levels for CLTA |
Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Differentially expressed gene analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
CB | DOWN | ENST00000493185.2 | CLTA-208:nonsense_mediated_decay:CLTA | 5.917381e+01 | -5.882110e+00 | 1.272997e-14 | 4.288016e-12 |
TC | DOWN | ENST00000493185.2 | CLTA-208:nonsense_mediated_decay:CLTA | 8.607490e+00 | -2.465891e+00 | 1.538269e-04 | 2.269636e-03 |
Landscape of isoform expressions across multiple brain tissues between AD and control. |
Top |
Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for CLTA |
Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
All exon skipping events in AD cohorts. |
Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
exon_skip_116310 | chr9 | 36204068:36204179:36263198:36263442:36265421:36265574 | 36263198:36263442 |
exon_skip_117288 | chr9 | 36197551:36197588:36198979:36199096:36204068:36204083 | 36198979:36199096 |
exon_skip_140283 | chr9 | 36197551:36197588:36198979:36199096:36204068:36204179 | 36198979:36199096 |
exon_skip_141791 | chr9 | 36191165:36191273:36197551:36197588:36204068:36204083 | 36197551:36197588 |
exon_skip_154113 | chr9 | 36191165:36191273:36197551:36197588:36204068:36204092 | 36197551:36197588 |
exon_skip_157218 | chr9 | 36204068:36204179:36209267:36209320:36211603:36211784 | 36209267:36209320 |
exon_skip_161254 | chr9 | 36209275:36209320:36210625:36210660:36211603:36211784 | 36210625:36210660 |
exon_skip_177484 | chr9 | 36204148:36204179:36209267:36209320:36211603:36211784 | 36209267:36209320 |
exon_skip_184620 | chr9 | 36209267:36209320:36210625:36210660:36211603:36211667 | 36210625:36210660 |
exon_skip_18735 | chr9 | 36197551:36197588:36198979:36199096:36204068:36204092 | 36198979:36199096 |
exon_skip_188492 | chr9 | 36204148:36204179:36210625:36210660:36211603:36211784 | 36210625:36210660 |
exon_skip_197636 | chr9 | 36204068:36204179:36209267:36209320:36211603:36211622 | 36209267:36209320 |
exon_skip_20381 | chr9 | 36209267:36209320:36210625:36210660:36211603:36211622 | 36210625:36210660 |
exon_skip_20661 | chr9 | 36191165:36191273:36197551:36197588:36198979:36199096 | 36197551:36197588 |
exon_skip_208450 | chr9 | 36204068:36204179:36210625:36210660:36211603:36211622 | 36210625:36210660 |
exon_skip_213353 | chr9 | 36209267:36209320:36210625:36210660:36211603:36211642 | 36210625:36210660 |
exon_skip_21342 | chr9 | 36204068:36204179:36210625:36210660:36211603:36211642 | 36210625:36210660 |
exon_skip_220150 | chr9 | 36204068:36204179:36210625:36210660:36211603:36211784 | 36210625:36210660 |
exon_skip_224708 | chr9 | 36209267:36209320:36210625:36210660:36211603:36211784 | 36210625:36210660 |
exon_skip_234606 | chr9 | 36204148:36204179:36209267:36209320:36210625:36210660 | 36209267:36209320 |
exon_skip_24195 | chr9 | 36191165:36191273:36197551:36197588:36204068:36204179 | 36197551:36197588 |
exon_skip_248532 | chr9 | 36198979:36199096:36204068:36204179:36209267:36209320 | 36204068:36204179 |
exon_skip_260780 | chr9 | 36204068:36204179:36209267:36209320:36210625:36210660 | 36209267:36209320 |
exon_skip_293137 | chr9 | 36191165:36191273:36197551:36197588:36204068:36204178 | 36197551:36197588 |
exon_skip_32312 | chr9 | 36197551:36197588:36198979:36199096:36204068:36204178 | 36198979:36199096 |
exon_skip_63501 | chr9 | 36204126:36204179:36209267:36209320:36210625:36210660 | 36209267:36209320 |
exon_skip_72802 | chr9 | 36204068:36204179:36209267:36209320:36211603:36211667 | 36209267:36209320 |
exon_skip_75354 | chr9 | 36204068:36204179:36210625:36210660:36211603:36211667 | 36210625:36210660 |
exon_skip_86818 | chr9 | 36204068:36204179:36209267:36209320:36211603:36211642 | 36209267:36209320 |
Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
exon_skip_157218 | MSBB_STG | 3.959701e-01 | 5.125000e-01 | -1.165299e-01 | 3.257582e-02 |
exon_skip_157218 | MSBB_PG | 2.391216e-01 | 4.516364e-01 | -2.125147e-01 | 2.111467e-08 |
Top |
Open reading frame (ORF) annotation in the exon skipping event for CLTA |
Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000242285 | 36197551 | 36197588 | Frame-shift |
ENST00000433436 | 36197551 | 36197588 | Frame-shift |
ENST00000242285 | 36198979 | 36199096 | Frame-shift |
ENST00000433436 | 36198979 | 36199096 | Frame-shift |
ENST00000242285 | 36209267 | 36209320 | In-frame |
ENST00000433436 | 36209267 | 36209320 | In-frame |
ENST00000242285 | 36210625 | 36210660 | In-frame |
Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000242285 | 36197551 | 36197588 | Frame-shift |
ENST00000433436 | 36197551 | 36197588 | Frame-shift |
ENST00000242285 | 36209267 | 36209320 | In-frame |
ENST00000433436 | 36209267 | 36209320 | In-frame |
ENST00000242285 | 36210625 | 36210660 | In-frame |
Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000242285 | 36197551 | 36197588 | Frame-shift |
ENST00000433436 | 36197551 | 36197588 | Frame-shift |
ENST00000242285 | 36198979 | 36199096 | Frame-shift |
ENST00000433436 | 36198979 | 36199096 | Frame-shift |
ENST00000242285 | 36204068 | 36204179 | Frame-shift |
ENST00000433436 | 36204068 | 36204179 | Frame-shift |
ENST00000242285 | 36209267 | 36209320 | In-frame |
ENST00000433436 | 36209267 | 36209320 | In-frame |
ENST00000242285 | 36210625 | 36210660 | In-frame |
Top |
Infer the effects of exon skipping event on protein functional features for CLTA |
p-ENSG00000122705_img4.png |
Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000242285 | 1169 | 248 | 36209267 | 36209320 | 607 | 659 | 162 | 179 |
ENST00000433436 | 1252 | 248 | 36209267 | 36209320 | 688 | 740 | 162 | 179 |
ENST00000242285 | 1169 | 248 | 36210625 | 36210660 | 661 | 695 | 180 | 191 |
Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000242285 | 1169 | 248 | 36209267 | 36209320 | 607 | 659 | 162 | 179 |
ENST00000433436 | 1252 | 248 | 36209267 | 36209320 | 688 | 740 | 162 | 179 |
ENST00000242285 | 1169 | 248 | 36210625 | 36210660 | 661 | 695 | 180 | 191 |
Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000242285 | 1169 | 248 | 36209267 | 36209320 | 607 | 659 | 162 | 179 |
ENST00000433436 | 1252 | 248 | 36209267 | 36209320 | 688 | 740 | 162 | 179 |
ENST00000242285 | 1169 | 248 | 36210625 | 36210660 | 661 | 695 | 180 | 191 |
Lost protein functional features of individual exon skipping events in ROSMAP. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
P09496 | 162 | 179 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
P09496 | 162 | 179 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
P09496 | 162 | 179 | 100 | 162 | Region | Note=Involved in binding clathrin heavy chain |
P09496 | 162 | 179 | 100 | 162 | Region | Note=Involved in binding clathrin heavy chain |
P09496 | 180 | 191 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 180 | 191 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 180 | 191 | 181 | 192 | Alternative sequence | ID=VSP_024238;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
P09496 | 180 | 191 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
Lost protein functional features of individual exon skipping events in MSBB. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
P09496 | 162 | 179 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
P09496 | 162 | 179 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
P09496 | 162 | 179 | 100 | 162 | Region | Note=Involved in binding clathrin heavy chain |
P09496 | 162 | 179 | 100 | 162 | Region | Note=Involved in binding clathrin heavy chain |
P09496 | 180 | 191 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 180 | 191 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 180 | 191 | 181 | 192 | Alternative sequence | ID=VSP_024238;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
P09496 | 180 | 191 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
Lost protein functional features of individual exon skipping events in Mayo. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
P09496 | 162 | 179 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 162 | 179 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
P09496 | 162 | 179 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
P09496 | 162 | 179 | 100 | 162 | Region | Note=Involved in binding clathrin heavy chain |
P09496 | 162 | 179 | 100 | 162 | Region | Note=Involved in binding clathrin heavy chain |
P09496 | 180 | 191 | 162 | 180 | Alternative sequence | ID=VSP_043239;Note=In isoform 4. RVADEAFYKQPFADVIGYV->S;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
P09496 | 180 | 191 | 163 | 192 | Alternative sequence | ID=VSP_001095;Note=In isoform Non-brain and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:3267234,ECO:0000303|Ref.2;Dbxref=PMID:14702039 |
P09496 | 180 | 191 | 181 | 192 | Alternative sequence | ID=VSP_024238;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
P09496 | 180 | 191 | 1 | 248 | Chain | ID=PRO_0000205767;Note=Clathrin light chain A |
Top |
3'-UTR located exon skipping events that lost miRNA binding sites in CLTA |
3'-UTR exon skipping evnets lost miRNA binding. |
Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
Top |
SNVs in the skipped exons for CLTA |
- Differential PSIs between mutated versus non-mutated samples. |
- Depth of Coverage in the skipped exon of the mutated samples. |
- Sashimi plot in the skipped exon of the mutated samples. |
- Non-synonymous mutations located in the skipped exons. |
Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
- Non-synonymous mutations located in the skipped exons in CCLE. |
Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
Top |
AD stage-associated exon skippint events for CLTA |
Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for CLTA |
sQTL information located at the skipped exons. |
Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
HCC | exon_skip_157218 | rs17778847 | chr9:36154414 | 6.373812e-04 | 4.104548e-02 |
Top |
Correlation with RNA binding proteins (RBPs) for CLTA |
Correlated RBP and related information. |
Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
CB | PCBP4 | exon_skip_234606 | 5.505908e-01 | 5.531244e-14 |
CB | PTBP1 | exon_skip_234606 | -4.083269e-01 | 9.145546e-08 |
CB | PCBP4 | exon_skip_177484 | 4.650319e-01 | 6.594069e-10 |
CB | PABPC1 | exon_skip_177484 | 5.603732e-01 | 1.583387e-14 |
CB | SRSF9 | exon_skip_177484 | 4.493864e-01 | 2.817858e-09 |
CB | CNOT4 | exon_skip_188492 | 4.585422e-01 | 1.215243e-09 |
CB | PABPC1 | exon_skip_161254 | -4.062364e-01 | 1.078673e-07 |
DLPFC | MBNL1 | exon_skip_197636 | 5.906732e-01 | 3.025708e-24 |
DLPFC | ILF2 | exon_skip_197636 | 6.855413e-01 | 4.476828e-35 |
DLPFC | HNRNPK | exon_skip_197636 | 6.354241e-01 | 6.961845e-29 |
DLPFC | PCBP4 | exon_skip_197636 | 5.013993e-01 | 7.114532e-17 |
DLPFC | PTBP3 | exon_skip_197636 | 6.288725e-01 | 3.708188e-28 |
DLPFC | HNRNPL | exon_skip_197636 | 7.423491e-01 | 8.404923e-44 |
DLPFC | PABPC1 | exon_skip_197636 | 5.177261e-01 | 4.595456e-18 |
DLPFC | EWSR1 | exon_skip_197636 | 6.815639e-01 | 1.540245e-34 |
DLPFC | SRSF9 | exon_skip_197636 | 6.657166e-01 | 1.752828e-32 |
DLPFC | ESRP1 | exon_skip_197636 | 6.971046e-01 | 1.098915e-36 |
DLPFC | MBNL1 | exon_skip_260780 | 4.155766e-01 | 1.032077e-15 |
DLPFC | PTBP3 | exon_skip_260780 | 4.711363e-01 | 2.678100e-20 |
DLPFC | HNRNPL | exon_skip_260780 | 4.137269e-01 | 1.420205e-15 |
DLPFC | ESRP1 | exon_skip_260780 | 4.003233e-01 | 1.354528e-14 |
DLPFC | CNOT4 | exon_skip_208450 | 5.541631e-01 | 5.806903e-21 |
DLPFC | MBNL1 | exon_skip_208450 | 4.891286e-01 | 5.074901e-16 |
DLPFC | KHDRBS3 | exon_skip_208450 | 7.013374e-01 | 2.705650e-37 |
DLPFC | HNRNPL | exon_skip_208450 | 5.383491e-01 | 1.161599e-19 |
DLPFC | PABPC1 | exon_skip_208450 | 4.018368e-01 | 7.610458e-11 |
DLPFC | SRSF9 | exon_skip_208450 | 4.861113e-01 | 8.129385e-16 |
DLPFC | NOVA1 | exon_skip_208450 | 6.477215e-01 | 2.697353e-30 |
FL | ILF2 | exon_skip_157218 | 5.435673e-01 | 1.286326e-16 |
FL | HNRNPK | exon_skip_157218 | 4.988482e-01 | 7.449761e-14 |
FL | PTBP1 | exon_skip_157218 | -4.440690e-01 | 5.635810e-11 |
FL | HNRNPL | exon_skip_157218 | 5.166635e-01 | 6.604238e-15 |
FL | SRSF9 | exon_skip_157218 | 4.219560e-01 | 5.962135e-10 |
FL | ESRP1 | exon_skip_157218 | 4.497061e-01 | 3.004591e-11 |
HCC | PTBP1 | exon_skip_157218 | -6.727790e-01 | 2.467053e-37 |
HCC | HNRNPF | exon_skip_157218 | -5.999553e-01 | 4.430705e-28 |
HCC | RBMS3 | exon_skip_220150 | -4.971123e-01 | 1.906219e-18 |
HCC | KHDRBS3 | exon_skip_220150 | -4.175330e-01 | 6.083328e-13 |
IFG | EWSR1 | exon_skip_260780 | 4.491522e-01 | 1.649968e-02 |
IFG | ESRP1 | exon_skip_260780 | 4.559373e-01 | 1.475119e-02 |
IFG | IGF2BP2 | exon_skip_157218 | -5.440833e-01 | 2.762997e-03 |
IFG | PTBP1 | exon_skip_157218 | -5.695510e-01 | 1.558789e-03 |
IFG | PABPC1 | exon_skip_157218 | -4.470154e-01 | 1.708453e-02 |
IFG | NOVA1 | exon_skip_220150 | 4.958187e-01 | 7.292769e-03 |
IFG | CNOT4 | exon_skip_224708 | 4.061131e-01 | 3.200403e-02 |
IFG | PABPC1 | exon_skip_224708 | 4.897235e-01 | 8.165207e-03 |
PCC | PTBP1 | exon_skip_260780 | -4.242009e-01 | 1.030912e-10 |
PCC | PTBP1 | exon_skip_86818 | -6.558421e-01 | 8.091281e-28 |
PCC | PABPC1 | exon_skip_86818 | -4.146381e-01 | 2.425294e-10 |
PCC | HNRNPF | exon_skip_86818 | -5.067398e-01 | 1.997412e-15 |
PG | PTBP1 | exon_skip_260780 | -4.448169e-01 | 1.369884e-09 |
PG | IGF2BP2 | exon_skip_157218 | -4.453596e-01 | 2.776947e-11 |
PG | ILF2 | exon_skip_157218 | 4.661031e-01 | 2.415044e-12 |
PG | HNRNPK | exon_skip_157218 | 4.634346e-01 | 3.337404e-12 |
PG | PTBP1 | exon_skip_157218 | -4.656932e-01 | 2.538535e-12 |
PG | HNRNPL | exon_skip_157218 | 4.865398e-01 | 1.843785e-13 |
PG | KHDRBS3 | exon_skip_220150 | 4.569196e-01 | 5.722016e-12 |
PG | NOVA1 | exon_skip_220150 | 4.021739e-01 | 2.267879e-09 |
STG | IGF2BP2 | exon_skip_157218 | -5.117154e-01 | 2.171708e-07 |
STG | PTBP1 | exon_skip_157218 | -5.577037e-01 | 9.320384e-09 |
STG | SRSF9 | exon_skip_157218 | 4.042266e-01 | 7.074926e-05 |
STG | KHDRBS3 | exon_skip_220150 | 4.008386e-01 | 8.239251e-05 |
TC | ILF2 | exon_skip_63501 | 4.614561e-01 | 8.181298e-10 |
TC | PTBP1 | exon_skip_63501 | -4.977942e-01 | 2.125029e-11 |
TC | ESRP1 | exon_skip_63501 | 6.141672e-01 | 5.790656e-18 |
TC | ILF2 | exon_skip_72802 | 4.631178e-01 | 6.987239e-10 |
TC | PTBP1 | exon_skip_72802 | -5.197560e-01 | 1.882354e-12 |
TC | PTBP3 | exon_skip_72802 | 4.238640e-01 | 2.336479e-08 |
TC | ESRP1 | exon_skip_72802 | 6.755447e-01 | 1.144603e-22 |
TC | ESRP1 | exon_skip_283040 | 4.690546e-01 | 3.033419e-09 |
TC | KHDRBS3 | exon_skip_75354 | 6.380988e-01 | 1.134094e-19 |
Top |
RelatedDrugs for CLTA |
Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for CLTA |
Diseases associated with this gene. (DisGeNet 4.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |