 Gene summary |
| Gene information | Gene symbol | OLFM3 |
Gene ID | 118427 | | Gene name | olfactomedin 3 |
| Synonyms | NOE3|NOELIN3|OPTIMEDIN |
| Cytomap | 1p21.1 |
| Type of gene | protein-coding |
| Description | noelin-3olfactomedin related ER localized protein 3 |
| Modification date | 20200313 |
| UniProtAcc | Q6IMJ0, Q96PB7, |
| Context | |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
ENSG00000118733
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
***cutpoints = c(0, 0.0001, 0.001, 0.01, 1), symbols = c("****", "***", "**", "ns")
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| PG | DOWN | 5.113901e+02 | -8.925869e-01 | 2.947139e-07 | 8.839212e-06 |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PG | DOWN | ENST00000370103.8 | OLFM3-202:protein_coding:OLFM3 | 3.281124e+02 | -9.308678e-01 | 2.237362e-06 | 1.653738e-04 |
| PG | DOWN | ENST00000338858.9 | OLFM3-201:protein_coding:OLFM3 | 1.091075e+02 | -8.629049e-01 | 3.979412e-04 | 7.499438e-03 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_125496 | chr1 | 101806076:101806182:101812410:101813146:101825026:101825245 | 101812410:101813146 |
| exon_skip_226820 | chr1 | 101806076:101806182:101812410:101813146:101825026:101825113 | 101812410:101813146 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
