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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for PACSIN2 |
 Gene summary |
| Gene information | Gene symbol | PACSIN2 | Gene ID | 11252 |
| Gene name | protein kinase C and casein kinase substrate in neurons 2 | |
| Synonyms | SDPII | |
| Cytomap | 22q13.2 | |
| Type of gene | protein-coding | |
| Description | protein kinase C and casein kinase substrate in neurons protein 2cytoplasmic phosphoprotein PACSIN2syndapin-2syndapin-IIsyndapin2 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| PACSIN2 | GO:0097320 | plasma membrane tubulation | 23596323 |
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Gene structures and expression levels for PACSIN2 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000100266
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for PACSIN2 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_137394 | chr22 | 42893574:42893613:42912021:42912157:42959799:42959881 | 42912021:42912157 |
| exon_skip_167320 | chr22 | 42893574:42893613:42912021:42912157:42959572:42959899 | 42912021:42912157 |
| exon_skip_195151 | chr22 | 42893574:42893613:42912021:42912157:43015021:43015098 | 42912021:42912157 |
| exon_skip_228415 | chr22 | 42879048:42879169:42880617:42880622:42882184:42882304 | 42880617:42880622 |
| exon_skip_242328 | chr22 | 42879061:42879169:42880617:42880622:42882184:42882304 | 42880617:42880622 |
| exon_skip_257801 | chr22 | 42884386:42884561:42888643:42888798:42890947:42891182 | 42888643:42888798 |
| exon_skip_294448 | chr22 | 42888643:42888798:42890947:42891182:42893457:42893613 | 42890947:42891182 |
| exon_skip_35614 | chr22 | 42879048:42879169:42882184:42882304:42884386:42884561 | 42882184:42882304 |
| exon_skip_77069 | chr22 | 42876137:42876333:42876888:42877010:42879048:42879169 | 42876888:42877010 |
| exon_skip_79561 | chr22 | 42893457:42893613:42909427:42909565:42912021:42912157 | 42909427:42909565 |
| exon_skip_9542 | chr22 | 42876137:42876333:42876888:42877010:42879048:42879166 | 42876888:42877010 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_228415 | ROSMAP_DLPFC | 2.944651e-01 | 4.032759e-01 | -1.088107e-01 | 6.573803e-04 |
| exon_skip_77069 | ROSMAP_PCC | 5.855385e-01 | 4.852941e-01 | 1.002443e-01 | 9.286202e-04 |
| exon_skip_228415 | ROSMAP_PCC | 3.974615e-01 | 4.994118e-01 | -1.019502e-01 | 9.517514e-04 |
| exon_skip_77069 | MSBB_STG | 3.137255e-01 | 2.134783e-01 | 1.002472e-01 | 4.882265e-03 |
| exon_skip_228415 | MSBB_STG | 5.318644e-01 | 6.485714e-01 | -1.167070e-01 | 4.851011e-02 |
| exon_skip_228415 | MSBB_FL | 4.842149e-01 | 6.077551e-01 | -1.235402e-01 | 9.024261e-03 |
| exon_skip_228415 | Mayo_TC | 2.351220e-01 | 3.432468e-01 | -1.081248e-01 | 5.667294e-03 |
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Open reading frame (ORF) annotation in the exon skipping event for PACSIN2 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000263246 | 42912021 | 42912157 | 3UTR-3CDS |
| ENST00000263246 | 42882184 | 42882304 | Frame-shift |
| ENST00000402229 | 42882184 | 42882304 | Frame-shift |
| ENST00000403744 | 42882184 | 42882304 | Frame-shift |
| ENST00000263246 | 42890947 | 42891182 | Frame-shift |
| ENST00000402229 | 42890947 | 42891182 | Frame-shift |
| ENST00000403744 | 42890947 | 42891182 | Frame-shift |
| ENST00000263246 | 42876888 | 42877010 | In-frame |
| ENST00000402229 | 42876888 | 42877010 | In-frame |
| ENST00000403744 | 42876888 | 42877010 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000263246 | 42912021 | 42912157 | 3UTR-3CDS |
| ENST00000263246 | 42882184 | 42882304 | Frame-shift |
| ENST00000402229 | 42882184 | 42882304 | Frame-shift |
| ENST00000403744 | 42882184 | 42882304 | Frame-shift |
| ENST00000263246 | 42890947 | 42891182 | Frame-shift |
| ENST00000402229 | 42890947 | 42891182 | Frame-shift |
| ENST00000403744 | 42890947 | 42891182 | Frame-shift |
| ENST00000263246 | 42876888 | 42877010 | In-frame |
| ENST00000402229 | 42876888 | 42877010 | In-frame |
| ENST00000403744 | 42876888 | 42877010 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000263246 | 42912021 | 42912157 | 3UTR-3CDS |
| ENST00000263246 | 42890947 | 42891182 | Frame-shift |
| ENST00000402229 | 42890947 | 42891182 | Frame-shift |
| ENST00000403744 | 42890947 | 42891182 | Frame-shift |
| ENST00000263246 | 42876888 | 42877010 | In-frame |
| ENST00000402229 | 42876888 | 42877010 | In-frame |
| ENST00000403744 | 42876888 | 42877010 | In-frame |
| ENST00000263246 | 42888643 | 42888798 | In-frame |
| ENST00000402229 | 42888643 | 42888798 | In-frame |
| ENST00000403744 | 42888643 | 42888798 | In-frame |
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Infer the effects of exon skipping event on protein functional features for PACSIN2 |
p-ENSG00000100266_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000263246 | 3266 | 486 | 42876888 | 42877010 | 1231 | 1352 | 343 | 383 |
| ENST00000402229 | 1900 | 486 | 42876888 | 42877010 | 1222 | 1343 | 343 | 383 |
| ENST00000403744 | 2127 | 486 | 42876888 | 42877010 | 1251 | 1372 | 343 | 383 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000263246 | 3266 | 486 | 42876888 | 42877010 | 1231 | 1352 | 343 | 383 |
| ENST00000402229 | 1900 | 486 | 42876888 | 42877010 | 1222 | 1343 | 343 | 383 |
| ENST00000403744 | 2127 | 486 | 42876888 | 42877010 | 1251 | 1372 | 343 | 383 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000263246 | 3266 | 486 | 42888643 | 42888798 | 656 | 810 | 151 | 202 |
| ENST00000402229 | 1900 | 486 | 42888643 | 42888798 | 647 | 801 | 151 | 202 |
| ENST00000403744 | 2127 | 486 | 42888643 | 42888798 | 676 | 830 | 151 | 202 |
| ENST00000263246 | 3266 | 486 | 42876888 | 42877010 | 1231 | 1352 | 343 | 383 |
| ENST00000402229 | 1900 | 486 | 42876888 | 42877010 | 1222 | 1343 | 343 | 383 |
| ENST00000403744 | 2127 | 486 | 42876888 | 42877010 | 1251 | 1372 | 343 | 383 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9UNF0 | 151 | 202 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 151 | 202 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 151 | 202 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 151 | 202 | 25 | 274 | Coiled coil | . |
| Q9UNF0 | 151 | 202 | 25 | 274 | Coiled coil | . |
| Q9UNF0 | 151 | 202 | 25 | 274 | Coiled coil | . |
| Q9UNF0 | 151 | 202 | 11 | 282 | Domain | Note=F-BAR;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01077 |
| Q9UNF0 | 151 | 202 | 11 | 282 | Domain | Note=F-BAR;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01077 |
| Q9UNF0 | 151 | 202 | 11 | 282 | Domain | Note=F-BAR;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01077 |
| Q9UNF0 | 151 | 202 | 129 | 169 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 129 | 169 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 129 | 169 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 172 | 177 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 172 | 177 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 172 | 177 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 185 | 188 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 185 | 188 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 185 | 188 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 189 | 191 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 189 | 191 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 189 | 191 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 197 | 255 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 197 | 255 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 197 | 255 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 175 | 175 | Natural variant | ID=VAR_053555;Note=N->S;Dbxref=dbSNP:rs35383004 |
| Q9UNF0 | 151 | 202 | 175 | 175 | Natural variant | ID=VAR_053555;Note=N->S;Dbxref=dbSNP:rs35383004 |
| Q9UNF0 | 151 | 202 | 175 | 175 | Natural variant | ID=VAR_053555;Note=N->S;Dbxref=dbSNP:rs35383004 |
| Q9UNF0 | 151 | 202 | 182 | 182 | Sequence conflict | Note=L->F;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 151 | 202 | 182 | 182 | Sequence conflict | Note=L->F;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 151 | 202 | 182 | 182 | Sequence conflict | Note=L->F;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 151 | 202 | 192 | 195 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 192 | 195 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 151 | 202 | 192 | 195 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3ABH |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 344 | 384 | Alternative sequence | ID=VSP_004517;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11230166,ECO:0000303|Ref.6;Dbxref=PMID:11230166 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 1 | 486 | Chain | ID=PRO_0000161795;Note=Protein kinase C and casein kinase substrate in neurons protein 2 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 362 | 364 | Motif | Note=NPF1 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9UNF0 | 343 | 383 | 378 | 380 | Sequence conflict | Note=DDT->EDI;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
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3'-UTR located exon skipping events that lost miRNA binding sites in PACSIN2 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for PACSIN2 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for PACSIN2 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PACSIN2 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for PACSIN2 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | PCBP2 | exon_skip_77069 | -4.805550e-01 | 1.449007e-10 |
| CB | G3BP2 | exon_skip_77069 | -4.624373e-01 | 8.432840e-10 |
| CB | TARDBP | exon_skip_228415 | 4.229270e-01 | 2.797260e-08 |
| CB | G3BP2 | exon_skip_228415 | 6.098603e-01 | 1.436230e-17 |
| CB | SRSF9 | exon_skip_228415 | 6.043786e-01 | 3.314479e-17 |
| CB | SRSF4 | exon_skip_195151 | -5.047999e-01 | 1.567890e-11 |
| CB | HNRNPF | exon_skip_195151 | -4.400928e-01 | 8.052704e-09 |
| DLPFC | G3BP2 | exon_skip_228415 | 7.174605e-01 | 1.340871e-53 |
| FL | SRSF2 | exon_skip_77069 | -4.941964e-01 | 3.645187e-12 |
| FL | HNRNPK | exon_skip_77069 | -4.966044e-01 | 2.760063e-12 |
| FL | G3BP2 | exon_skip_77069 | -6.452256e-01 | 5.540391e-22 |
| FL | KHDRBS2 | exon_skip_77069 | -4.490083e-01 | 4.596040e-10 |
| FL | EIF4G2 | exon_skip_77069 | -4.103617e-01 | 1.699699e-08 |
| FL | CELF1 | exon_skip_77069 | -4.031763e-01 | 3.167530e-08 |
| FL | SRSF1 | exon_skip_77069 | -4.120427e-01 | 1.466231e-08 |
| FL | SRSF9 | exon_skip_77069 | -5.387213e-01 | 1.469692e-14 |
| FL | G3BP2 | exon_skip_228415 | 6.823159e-01 | 1.246292e-24 |
| FL | SRSF9 | exon_skip_228415 | 5.221577e-01 | 2.823462e-13 |
| HCC | RBM6 | exon_skip_77069 | 4.391535e-01 | 2.678535e-14 |
| HCC | RBM5 | exon_skip_77069 | 4.196709e-01 | 4.511303e-13 |
| HCC | PCBP4 | exon_skip_77069 | 4.241084e-01 | 2.409101e-13 |
| HCC | G3BP2 | exon_skip_77069 | -4.040240e-01 | 3.833423e-12 |
| HCC | G3BP2 | exon_skip_228415 | 4.608470e-01 | 9.262038e-16 |
| IFG | G3BP2 | exon_skip_77069 | -7.129160e-01 | 2.069970e-05 |
| IFG | KHDRBS2 | exon_skip_77069 | -5.072672e-01 | 5.865611e-03 |
| IFG | NUP42 | exon_skip_77069 | -4.277496e-01 | 2.317010e-02 |
| IFG | G3BP2 | exon_skip_228415 | 6.195658e-01 | 4.383136e-04 |
| IFG | RALYL | exon_skip_195151 | -4.417337e-01 | 1.860377e-02 |
| PCC | RBM6 | exon_skip_77069 | 5.087245e-01 | 1.490166e-15 |
| PCC | PCBP4 | exon_skip_77069 | 4.021094e-01 | 9.235697e-10 |
| PCC | G3BP2 | exon_skip_77069 | -7.142937e-01 | 7.361867e-35 |
| PCC | G3BP2 | exon_skip_228415 | 7.851512e-01 | 3.285436e-46 |
| PG | SRSF2 | exon_skip_77069 | -5.741176e-01 | 1.583285e-14 |
| PG | SRSF11 | exon_skip_77069 | -5.464981e-01 | 4.684243e-13 |
| PG | PCBP1 | exon_skip_77069 | -5.392417e-01 | 1.084455e-12 |
| PG | HNRNPK | exon_skip_77069 | -6.161249e-01 | 4.775236e-17 |
| PG | PCBP2 | exon_skip_77069 | -4.753125e-01 | 7.938740e-10 |
| PG | G3BP2 | exon_skip_77069 | -8.238552e-01 | 2.549876e-38 |
| PG | KHDRBS2 | exon_skip_77069 | -7.065003e-01 | 5.532760e-24 |
| PG | NUP42 | exon_skip_77069 | -6.072419e-01 | 1.750512e-16 |
| PG | EIF4G2 | exon_skip_77069 | -6.078666e-01 | 1.599796e-16 |
| PG | CELF1 | exon_skip_77069 | -6.510225e-01 | 1.902639e-19 |
| PG | SRSF1 | exon_skip_77069 | -5.627534e-01 | 6.627790e-14 |
| PG | SRSF9 | exon_skip_77069 | -5.530607e-01 | 2.154243e-13 |
| STG | G3BP2 | exon_skip_77069 | -4.738890e-01 | 2.000997e-05 |
| STG | KHDRBS2 | exon_skip_77069 | -4.228849e-01 | 1.743232e-04 |
| STG | G3BP2 | exon_skip_228415 | 4.941437e-01 | 3.188254e-06 |
| TC | SRSF2 | exon_skip_77069 | -4.182975e-01 | 3.710679e-08 |
| TC | G3BP2 | exon_skip_77069 | -6.582895e-01 | 3.106007e-21 |
| TC | KHDRBS2 | exon_skip_77069 | -7.719732e-01 | 6.629766e-33 |
| TC | NUP42 | exon_skip_77069 | -5.857782e-01 | 4.070952e-16 |
| TC | CELF1 | exon_skip_77069 | -5.361941e-01 | 2.728499e-13 |
| TC | G3BP2 | exon_skip_228415 | 7.327397e-01 | 4.908393e-28 |
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RelatedDrugs for PACSIN2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PACSIN2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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