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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for ZNF266 |
 Gene summary |
| Gene information | Gene symbol | ZNF266 | Gene ID | 10781 |
| Gene name | zinc finger protein 266 | |
| Synonyms | HZF1 | |
| Cytomap | 19p13.2 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 266zinc finger protein 1zinc finger protein HZF1 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for ZNF266 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000174652
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PG | UP | ENST00000590306.5 | ZNF266-203:protein_coding:ZNF266 | 5.210305e+00 | 3.925165e+00 | 2.296163e-04 | 5.046752e-03 |
| CB | DOWN | ENST00000588933.5 | ZNF266-202:protein_coding:ZNF266 | 9.854098e+01 | -1.573996e+00 | 1.443233e-05 | 1.437704e-04 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for ZNF266 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_10808 | chr19 | 9418509:9418631:9418766:9418895:9419051:9419299 | 9418766:9418895 |
| exon_skip_114403 | chr19 | 9418505:9418631:9418766:9418895:9419051:9419167 | 9418766:9418895 |
| exon_skip_1151 | chr19 | 9418505:9418631:9418762:9418895:9419051:9419167 | 9418762:9418895 |
| exon_skip_128360 | chr19 | 9418505:9418631:9418762:9419299:9420065:9420218 | 9418762:9419299 |
| exon_skip_133578 | chr19 | 9414708:9414720:9415654:9415742:9417828:9417908 | 9415654:9415742 |
| exon_skip_13513 | chr19 | 9418505:9418631:9418766:9418895:9419051:9419143 | 9418766:9418895 |
| exon_skip_14612 | chr19 | 9434110:9434235:9434798:9434859:9435108:9435193 | 9434798:9434859 |
| exon_skip_148569 | chr19 | 9433668:9433786:9434075:9434235:9434798:9434859 | 9434075:9434235 |
| exon_skip_182762 | chr19 | 9418505:9418631:9418762:9418895:9419051:9419299 | 9418762:9418895 |
| exon_skip_189242 | chr19 | 9418509:9418631:9418766:9418895:9419051:9419167 | 9418766:9418895 |
| exon_skip_199776 | chr19 | 9434075:9434235:9434798:9434859:9435108:9435193 | 9434798:9434859 |
| exon_skip_205978 | chr19 | 9420065:9420218:9433668:9433783:9434075:9434235 | 9433668:9433783 |
| exon_skip_207971 | chr19 | 9420065:9420218:9434065:9434235:9434798:9434859 | 9434065:9434235 |
| exon_skip_211385 | chr19 | 9418509:9418631:9418762:9418895:9419051:9419167 | 9418762:9418895 |
| exon_skip_221791 | chr19 | 9420065:9420218:9434798:9434859:9435108:9435193 | 9434798:9434859 |
| exon_skip_274573 | chr19 | 9433668:9433786:9434075:9434235:9435108:9435193 | 9434075:9434235 |
| exon_skip_276891 | chr19 | 9418505:9418631:9418766:9418895:9419051:9419299 | 9418766:9418895 |
| exon_skip_293461 | chr19 | 9420065:9420218:9433668:9433786:9434075:9434235 | 9433668:9433786 |
| exon_skip_44221 | chr19 | 9418505:9418631:9419217:9419299:9420065:9420218 | 9419217:9419299 |
| exon_skip_59487 | chr19 | 9418505:9418631:9419051:9419299:9420065:9420218 | 9419051:9419299 |
| exon_skip_59996 | chr19 | 9418509:9418631:9418762:9418895:9419051:9419299 | 9418762:9418895 |
| exon_skip_67409 | chr19 | 9418505:9418631:9418762:9418895:9419051:9419143 | 9418762:9418895 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_221791 | Mayo_CB | 4.997333e-01 | 6.029091e-01 | -1.031758e-01 | 2.777194e-05 |
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Open reading frame (ORF) annotation in the exon skipping event for ZNF266 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000590306 | 9418762 | 9418895 | 3UTR-3UTR |
| ENST00000588933 | 9418766 | 9418895 | 3UTR-3UTR |
| ENST00000590306 | 9433668 | 9433786 | 3UTR-3UTR |
| ENST00000588933 | 9434065 | 9434235 | 3UTR-3UTR |
| ENST00000588221 | 9434798 | 9434859 | 3UTR-3UTR |
| ENST00000588933 | 9434798 | 9434859 | 3UTR-3UTR |
| ENST00000588221 | 9415654 | 9415742 | Frame-shift |
| ENST00000588933 | 9415654 | 9415742 | Frame-shift |
| ENST00000590306 | 9415654 | 9415742 | Frame-shift |
| ENST00000592292 | 9415654 | 9415742 | Frame-shift |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000590306 | 9418762 | 9418895 | 3UTR-3UTR |
| ENST00000588933 | 9418766 | 9418895 | 3UTR-3UTR |
| ENST00000590306 | 9433668 | 9433786 | 3UTR-3UTR |
| ENST00000588933 | 9434065 | 9434235 | 3UTR-3UTR |
| ENST00000588221 | 9434798 | 9434859 | 3UTR-3UTR |
| ENST00000588221 | 9415654 | 9415742 | Frame-shift |
| ENST00000588933 | 9415654 | 9415742 | Frame-shift |
| ENST00000590306 | 9415654 | 9415742 | Frame-shift |
| ENST00000592292 | 9415654 | 9415742 | Frame-shift |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000588221 | 9418762 | 9419299 | 3UTR-3UTR |
| ENST00000590306 | 9418762 | 9418895 | 3UTR-3UTR |
| ENST00000588933 | 9418766 | 9418895 | 3UTR-3UTR |
| ENST00000592292 | 9419051 | 9419299 | 3UTR-3UTR |
| ENST00000590306 | 9433668 | 9433786 | 3UTR-3UTR |
| ENST00000588933 | 9434065 | 9434235 | 3UTR-3UTR |
| ENST00000590306 | 9434075 | 9434235 | 3UTR-3UTR |
| ENST00000588221 | 9434798 | 9434859 | 3UTR-3UTR |
| ENST00000588933 | 9434798 | 9434859 | 3UTR-3UTR |
| ENST00000588221 | 9415654 | 9415742 | Frame-shift |
| ENST00000588933 | 9415654 | 9415742 | Frame-shift |
| ENST00000590306 | 9415654 | 9415742 | Frame-shift |
| ENST00000592292 | 9415654 | 9415742 | Frame-shift |
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Infer the effects of exon skipping event on protein functional features for ZNF266 |
p-ENSG00000174652_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Top |
3'-UTR located exon skipping events that lost miRNA binding sites in ZNF266 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-3659 | chr19:9418953-9418960 | 8mer-1a | chr19:9418935-9418961 | 147.00 | -22.77 |
| Mayo | ENST00000590306 | 9433668 | 9433786 | hsa-miR-3663-5p | chr19:9433752-9433759 | 8mer-1a | chr19:9433741-9433763 | 151.00 | -17.24 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-1279 | chr19:9419051-9419058 | 8mer-1a | chr19:9419047-9419070 | 148.00 | -19.88 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-7855-5p | chr19:9419046-9419053 | 8mer-1a | chr19:9419039-9419062 | 152.00 | -14.04 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-487a-3p | chr19:9419180-9419187 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-487a-3p | chr19:9419180-9419187 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-154-3p | chr19:9419180-9419187 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-154-3p | chr19:9419180-9419187 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-4710 | chr19:9419045-9419052 | 8mer-1a | chr19:9419039-9419062 | 152.00 | -14.04 |
| Mayo | ENST00000588933 | 9434065 | 9434235 | hsa-miR-3179 | chr19:9434165-9434172 | 8mer-1a | chr19:9434152-9434173 | 154.00 | -15.29 |
| Mayo | ENST00000590306 | 9434075 | 9434235 | hsa-miR-3179 | chr19:9434165-9434172 | 8mer-1a | chr19:9434152-9434173 | 154.00 | -15.29 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-195-3p | chr19:9419010-9419017 | 8mer-1a | chr19:9418996-9419017 | 149.00 | -10.12 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-4733-3p | chr19:9419167-9419174 | 8mer-1a | chr19:9419152-9419174 | 156.00 | -18.10 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-4733-3p | chr19:9419167-9419174 | 8mer-1a | chr19:9419152-9419174 | 156.00 | -18.10 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-10226 | chr19:9418807-9418814 | 8mer-1a | chr19:9418791-9418816 | 158.00 | -22.33 |
| Mayo | ENST00000588933 | 9418766 | 9418895 | hsa-miR-10226 | chr19:9418807-9418814 | 8mer-1a | chr19:9418791-9418816 | 158.00 | -22.33 |
| Mayo | ENST00000590306 | 9418762 | 9418895 | hsa-miR-10226 | chr19:9418807-9418814 | 8mer-1a | chr19:9418791-9418816 | 158.00 | -22.33 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-6868-3p | chr19:9419150-9419157 | 8mer-1a | chr19:9419149-9419170 | 149.00 | -17.13 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-6790-5p | chr19:9418954-9418961 | 8mer-1a | chr19:9418935-9418961 | 147.00 | -22.77 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-6797-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| Mayo | ENST00000588933 | 9418766 | 9418895 | hsa-miR-6797-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| Mayo | ENST00000590306 | 9418762 | 9418895 | hsa-miR-6797-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-515-5p | chr19:9419190-9419197 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-515-5p | chr19:9419190-9419197 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-519e-5p | chr19:9419190-9419197 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-519e-5p | chr19:9419190-9419197 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-519d-5p | chr19:9419189-9419196 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-519d-5p | chr19:9419189-9419196 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000590306 | 9433668 | 9433786 | hsa-miR-4435 | chr19:9433760-9433767 | 8mer-1a | chr19:9433759-9433781 | 174.00 | -24.95 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-561-5p | chr19:9419098-9419105 | 8mer-1a | chr19:9419093-9419112 | 157.00 | -19.77 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-561-5p | chr19:9419098-9419105 | 8mer-1a | chr19:9419093-9419112 | 157.00 | -19.77 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-1245b-3p | chr19:9418843-9418850 | 8mer-1a | chr19:9418837-9418858 | 167.00 | -17.21 |
| Mayo | ENST00000588933 | 9418766 | 9418895 | hsa-miR-1245b-3p | chr19:9418843-9418850 | 8mer-1a | chr19:9418837-9418858 | 167.00 | -17.21 |
| Mayo | ENST00000590306 | 9418762 | 9418895 | hsa-miR-1245b-3p | chr19:9418843-9418850 | 8mer-1a | chr19:9418837-9418858 | 167.00 | -17.21 |
| Mayo | ENST00000588933 | 9434065 | 9434235 | hsa-miR-4786-5p | chr19:9434198-9434205 | 8mer-1a | chr19:9434189-9434210 | 161.00 | -22.65 |
| Mayo | ENST00000590306 | 9434075 | 9434235 | hsa-miR-4786-5p | chr19:9434198-9434205 | 8mer-1a | chr19:9434189-9434210 | 161.00 | -22.65 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-1-5p | chr19:9419178-9419185 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-1-5p | chr19:9419178-9419185 | 8mer-1a | chr19:9419174-9419197 | 166.00 | -15.81 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-1249-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| Mayo | ENST00000588933 | 9418766 | 9418895 | hsa-miR-1249-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| Mayo | ENST00000590306 | 9418762 | 9418895 | hsa-miR-1249-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-16-2-3p | chr19:9419010-9419017 | 8mer-1a | chr19:9418996-9419017 | 149.00 | -10.12 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-4658 | chr19:9418954-9418961 | 8mer-1a | chr19:9418935-9418961 | 147.00 | -22.77 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-320a-5p | chr19:9419193-9419200 | 8mer-1a | chr19:9419181-9419201 | 141.00 | -20.42 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-7112-3p | chr19:9419171-9419178 | 8mer-1a | chr19:9419166-9419187 | 153.00 | -15.94 |
| Mayo | ENST00000592292 | 9419051 | 9419299 | hsa-miR-7112-3p | chr19:9419171-9419178 | 8mer-1a | chr19:9419166-9419187 | 153.00 | -15.94 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-4475 | chr19:9418934-9418941 | 8mer-1a | chr19:9418922-9418942 | 170.00 | -26.94 |
| Mayo | ENST00000588221 | 9418762 | 9419299 | hsa-miR-767-3p | chr19:9418875-9418882 | 8mer-1a | chr19:9418862-9418884 | 149.00 | -15.82 |
| Mayo | ENST00000588933 | 9418766 | 9418895 | hsa-miR-767-3p | chr19:9418875-9418882 | 8mer-1a | chr19:9418862-9418884 | 149.00 | -15.82 |
| Mayo | ENST00000590306 | 9418762 | 9418895 | hsa-miR-767-3p | chr19:9418875-9418882 | 8mer-1a | chr19:9418862-9418884 | 149.00 | -15.82 |
| MSBB | ENST00000590306 | 9433668 | 9433786 | hsa-miR-3663-5p | chr19:9433752-9433759 | 8mer-1a | chr19:9433741-9433763 | 151.00 | -17.24 |
| MSBB | ENST00000588933 | 9434065 | 9434235 | hsa-miR-3179 | chr19:9434165-9434172 | 8mer-1a | chr19:9434152-9434173 | 154.00 | -15.29 |
| MSBB | ENST00000588933 | 9418766 | 9418895 | hsa-miR-10226 | chr19:9418807-9418814 | 8mer-1a | chr19:9418791-9418816 | 158.00 | -22.33 |
| MSBB | ENST00000590306 | 9418762 | 9418895 | hsa-miR-10226 | chr19:9418807-9418814 | 8mer-1a | chr19:9418791-9418816 | 158.00 | -22.33 |
| MSBB | ENST00000588933 | 9418766 | 9418895 | hsa-miR-6797-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| MSBB | ENST00000590306 | 9418762 | 9418895 | hsa-miR-6797-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| MSBB | ENST00000590306 | 9433668 | 9433786 | hsa-miR-4435 | chr19:9433760-9433767 | 8mer-1a | chr19:9433759-9433781 | 174.00 | -24.95 |
| MSBB | ENST00000588933 | 9418766 | 9418895 | hsa-miR-1245b-3p | chr19:9418843-9418850 | 8mer-1a | chr19:9418837-9418858 | 167.00 | -17.21 |
| MSBB | ENST00000590306 | 9418762 | 9418895 | hsa-miR-1245b-3p | chr19:9418843-9418850 | 8mer-1a | chr19:9418837-9418858 | 167.00 | -17.21 |
| MSBB | ENST00000588933 | 9434065 | 9434235 | hsa-miR-4786-5p | chr19:9434198-9434205 | 8mer-1a | chr19:9434189-9434210 | 161.00 | -22.65 |
| MSBB | ENST00000588933 | 9418766 | 9418895 | hsa-miR-1249-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| MSBB | ENST00000590306 | 9418762 | 9418895 | hsa-miR-1249-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| MSBB | ENST00000588933 | 9418766 | 9418895 | hsa-miR-767-3p | chr19:9418875-9418882 | 8mer-1a | chr19:9418862-9418884 | 149.00 | -15.82 |
| MSBB | ENST00000590306 | 9418762 | 9418895 | hsa-miR-767-3p | chr19:9418875-9418882 | 8mer-1a | chr19:9418862-9418884 | 149.00 | -15.82 |
| ROSMAP | ENST00000590306 | 9433668 | 9433786 | hsa-miR-3663-5p | chr19:9433752-9433759 | 8mer-1a | chr19:9433741-9433763 | 151.00 | -17.24 |
| ROSMAP | ENST00000588933 | 9434065 | 9434235 | hsa-miR-3179 | chr19:9434165-9434172 | 8mer-1a | chr19:9434152-9434173 | 154.00 | -15.29 |
| ROSMAP | ENST00000588933 | 9418766 | 9418895 | hsa-miR-10226 | chr19:9418807-9418814 | 8mer-1a | chr19:9418791-9418816 | 158.00 | -22.33 |
| ROSMAP | ENST00000590306 | 9418762 | 9418895 | hsa-miR-10226 | chr19:9418807-9418814 | 8mer-1a | chr19:9418791-9418816 | 158.00 | -22.33 |
| ROSMAP | ENST00000588933 | 9418766 | 9418895 | hsa-miR-6797-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| ROSMAP | ENST00000590306 | 9418762 | 9418895 | hsa-miR-6797-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| ROSMAP | ENST00000590306 | 9433668 | 9433786 | hsa-miR-4435 | chr19:9433760-9433767 | 8mer-1a | chr19:9433759-9433781 | 174.00 | -24.95 |
| ROSMAP | ENST00000588933 | 9418766 | 9418895 | hsa-miR-1245b-3p | chr19:9418843-9418850 | 8mer-1a | chr19:9418837-9418858 | 167.00 | -17.21 |
| ROSMAP | ENST00000590306 | 9418762 | 9418895 | hsa-miR-1245b-3p | chr19:9418843-9418850 | 8mer-1a | chr19:9418837-9418858 | 167.00 | -17.21 |
| ROSMAP | ENST00000588933 | 9434065 | 9434235 | hsa-miR-4786-5p | chr19:9434198-9434205 | 8mer-1a | chr19:9434189-9434210 | 161.00 | -22.65 |
| ROSMAP | ENST00000588933 | 9418766 | 9418895 | hsa-miR-1249-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| ROSMAP | ENST00000590306 | 9418762 | 9418895 | hsa-miR-1249-5p | chr19:9418853-9418860 | 8mer-1a | chr19:9418835-9418860 | 157.00 | -26.01 |
| ROSMAP | ENST00000588933 | 9418766 | 9418895 | hsa-miR-767-3p | chr19:9418875-9418882 | 8mer-1a | chr19:9418862-9418884 | 149.00 | -15.82 |
| ROSMAP | ENST00000590306 | 9418762 | 9418895 | hsa-miR-767-3p | chr19:9418875-9418882 | 8mer-1a | chr19:9418862-9418884 | 149.00 | -15.82 |
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SNVs in the skipped exons for ZNF266 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for ZNF266 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZNF266 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
| CB | exon_skip_221791 | rs6512110 | chr19:9412048 | 7.489054e-05 | 1.369898e-02 |
| CB | exon_skip_221791 | rs13535 | chr19:9343497 | 1.526376e-04 | 2.419689e-02 |
| CB | exon_skip_221791 | rs2217652 | chr19:9380138 | 1.526376e-04 | 2.419689e-02 |
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Correlation with RNA binding proteins (RBPs) for ZNF266 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | PCBP4 | exon_skip_221791 | 4.246489e-01 | 4.768798e-07 |
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RelatedDrugs for ZNF266 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF266 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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