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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in RPSMAP, MSBB, and Mayo

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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3'-UTR located exon skipping events lost miRNA binding sites

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SNVs in the skipped exons with depth of coverage

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AD stage-associated exon skipping events

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Correlation with RNA binding proteins (RBPs)

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Related drugs with this gene

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Related diseases with this gene

Gene summary for RTN3

check button Gene summary
Gene informationGene symbol

RTN3

Gene ID

10313

Gene namereticulon 3
SynonymsASYIP|HAP|NSPL2|NSPLII|RTN3-A1
Cytomap

11q13.1

Type of geneprotein-coding
Descriptionreticulon-3ASY interacting proteinNSP-like protein 2NSP-like protein IIhomolog of ASY proteinneuroendocrine-specific protein-like 2neuroendocrine-specific protein-like II
Modification date20200327
UniProtAcc

A0A024R5C4,

B7Z4M1,

F5GWG7,

F5H617,

F5H891,

O95197,

Q7RTN4,

Context- 27883331(Effects of Altered RTN3 Expression on BACE1 Activity and Alzheimer's Neuritic Plaques)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
RTN3

GO:0071787

endoplasmic reticulum tubular network formation

25612671


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Gene structures and expression levels for RTN3

check buttonSkipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

ENSG00000133318
check button Differentially expressed gene analysis across multiple brain tissues between AD and control.
Tissue typeDEG directionBase mean exp.log2FC(AD/control)P-valueAdj. p-value

check button Differentially expressed isoform analysis across multiple brain tissues between AD and control.
gencode gene structure
Tissue typeDEG directionENSTTranscript info.Base mean exp.log2FC(AD/control)P-valueAdjc. p-value
PGDOWNENST00000545432.5RTN3-214:protein_coding:RTN32.772795e+00-9.141061e-011.317319e-043.365350e-03
PGDOWNENST00000234347.10PRTN3-201:protein_coding:PRTN31.619879e+00-9.268314e-015.060568e-048.907658e-03
CBUPENST00000543123.1RTN3-212:retained_intron:RTN35.120522e+018.456341e-011.243067e-121.786756e-10
CBUPENST00000354497.4RTN3-204:protein_coding:RTN32.665876e+012.058503e+005.087756e-125.699529e-10
CBUPENST00000536011.5RTN3-207:nonsense_mediated_decay:RTN35.376241e+002.627848e+004.602197e-102.306029e-08
CBUPENST00000543552.5RTN3-213:protein_coding:RTN32.547356e+008.815397e-011.113831e-035.654789e-03
TCDOWNENST00000234347.10PRTN3-201:protein_coding:PRTN31.065023e+01-8.270473e-018.650290e-048.833044e-03

check button Landscape of isoform expressions across multiple brain tissues between AD and control.
gencode gene structure

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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for RTN3

check button Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap).
boxplot

check button All exon skipping events in AD cohorts.
Exon skip IDchrExons involved in exon skippingSkipped exon
exon_skip_102867chr1163753662:63753708:63756112:63756170:63758156:6375824063756112:63756170
exon_skip_105577chr1163681718:63681778:63746947:63747024:63749991:6375019863746947:63747024
exon_skip_10647chr1163681573:63681778:63746947:63747024:63749991:6375005663746947:63747024
exon_skip_111759chr1163753662:63753708:63756112:63756170:63758156:6375819663756112:63756170
exon_skip_112570chr1163750075:63750198:63756112:63756170:63758156:6375842163756112:63756170
exon_skip_115006chr1163753662:63753708:63756112:63756170:63758156:6375822863756112:63756170
exon_skip_118400chr1163681597:63681778:63704851:63704907:63718981:6371918963704851:63704907
exon_skip_134894chr1163681597:63681778:63704851:63704907:63718702:6372103263704851:63704907
exon_skip_136874chr1163681573:63681778:63718702:63721032:63749991:6375005663718702:63721032
exon_skip_13831chr1163681573:63681778:63704851:63704907:63718702:6372103263704851:63704907
exon_skip_140859chr1163753662:63753708:63756112:63756170:63758156:6375817763756112:63756170
exon_skip_145285chr1163681573:63681778:63718981:63721032:63749991:6375005663718981:63721032
exon_skip_146554chr1163681573:63681778:63704851:63704907:63718981:6371918963704851:63704907
exon_skip_146845chr1163681573:63681778:63704851:63704907:63749991:6375019763704851:63704907
exon_skip_149971chr1163681573:63681778:63749991:63750198:63756112:6375617063749991:63750198
exon_skip_160375chr1163681718:63681778:63704851:63704907:63749991:6375019863704851:63704907
exon_skip_168608chr1163749991:63750198:63756112:63756170:63758156:6375818463756112:63756170
exon_skip_177360chr1163681573:63681778:63704851:63704907:63749991:6375005663704851:63704907
exon_skip_180808chr1163681573:63681778:63718981:63721032:63749991:6375019763718981:63721032
exon_skip_185561chr1163681573:63681778:63749991:63750198:63753069:6375313863749991:63750198
exon_skip_187953chr1163750136:63750198:63752507:63752645:63753069:6375313863752507:63752645
exon_skip_189506chr1163681458:63681778:63746947:63747024:63749991:6375019863746947:63747024
exon_skip_193411chr1163681718:63681778:63718702:63721032:63749991:6375019863718702:63721032
exon_skip_193979chr1163750075:63750198:63752507:63752645:63753069:6375313863752507:63752645
exon_skip_194807chr1163750075:63750198:63756112:63756170:63758156:6375822563756112:63756170
exon_skip_203781chr1163681573:63681778:63718981:63721032:63749991:6375019863718981:63721032
exon_skip_207991chr1163681573:63681778:63718702:63721032:63749991:6375019863718702:63721032
exon_skip_214509chr1163681474:63681778:63704851:63704907:63713971:6371447963704851:63704907
exon_skip_220985chr1163681573:63681778:63718702:63721032:63749991:6375019763718702:63721032
exon_skip_225573chr1163704851:63704907:63718702:63721032:63749991:6375019863718702:63721032
exon_skip_231525chr1163681718:63681778:63718981:63721032:63749991:6375019863718981:63721032
exon_skip_233521chr1163704880:63704907:63718702:63721032:63749991:6375019863718702:63721032
exon_skip_257322chr1163749991:63750198:63756112:63756170:63758156:6375842163756112:63756170
exon_skip_259406chr1163681718:63681778:63704851:63704907:63718702:6372103263704851:63704907
exon_skip_261656chr1163681573:63681778:63746947:63747024:63749991:6375019863746947:63747024
exon_skip_265007chr1163704851:63704907:63718702:63721032:63749991:6375005663718702:63721032
exon_skip_265377chr1163704851:63704907:63718702:63721032:63749991:6375019763718702:63721032
exon_skip_265430chr1163681718:63681778:63704851:63704907:63718981:6371918963704851:63704907
exon_skip_275159chr1163753662:63753708:63756112:63756170:63758156:6375816863756112:63756170
exon_skip_276513chr1163753662:63753708:63756112:63756170:63758156:6375842163756112:63756170
exon_skip_288472chr1163681458:63681778:63746947:63747024:63749991:6375019763746947:63747024
exon_skip_31543chr1163750075:63750198:63756112:63756170:63758156:6375839263756112:63756170
exon_skip_32816chr1163753681:63753708:63756112:63756170:63758156:6375842163756112:63756170
exon_skip_34660chr1163752507:63752645:63753069:63753138:63753662:6375370863753069:63753138
exon_skip_37484chr1163749991:63750198:63753069:63753138:63753662:6375370863753069:63753138
exon_skip_38960chr1163681483:63681778:63704851:63704907:63718702:6371999463704851:63704907
exon_skip_67936chr1163681573:63681778:63749991:63750198:63756112:6375616863749991:63750198
exon_skip_8534chr1163753662:63753708:63756112:63756170:63758156:6375818463756112:63756170
exon_skip_89864chr1163681573:63681778:63704851:63704907:63749991:6375019863704851:63704907
exon_skip_92724chr1163752588:63752645:63753069:63753138:63753662:6375370863753069:63753138
exon_skip_9344chr1163750075:63750198:63752507:63752645:63753069:6375313763752507:63752645
exon_skip_95254chr1163750075:63750198:63753069:63753138:63753662:6375370863753069:63753138
exon_skip_95479chr1163681573:63681778:63704851:63704907:63713971:6371416663704851:63704907

check button Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control.
Exon skipping informationTissue typeAvg(PSIs) in ADAvg(PSIs) in controlDifference (PSI)Adj. p-value


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Open reading frame (ORF) annotation in the exon skipping event for RTN3

check button Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003778196375250763752645Frame-shift
ENST000003778196375306963753138Frame-shift
ENST000003778196375611263756170Frame-shift
ENST000003778196370485163704907In-frame
ENST000003778196371870263721032In-frame

check button Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003778196375250763752645Frame-shift
ENST000003778196375306963753138Frame-shift
ENST000003778196375611263756170Frame-shift
ENST000003778196370485163704907In-frame
ENST000003778196371870263721032In-frame

check button Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003778196375250763752645Frame-shift
ENST000003778196375306963753138Frame-shift
ENST000003778196375611263756170Frame-shift
ENST000003778196370485163704907In-frame
ENST000003778196371870263721032In-frame

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Infer the effects of exon skipping event on protein functional features for RTN3

p-ENSG00000133318_img4.png
boxplot

check button Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003778194954103263704851637049072983534866
ENST00000377819495410326371870263721032355268467843

check button Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003778194954103263704851637049072983534866
ENST00000377819495410326371870263721032355268467843

check button Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003778194954103263704851637049072983534866
ENST00000377819495410326371870263721032355268467843

check button Lost protein functional features of individual exon skipping events in ROSMAP.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O95197486648843Alternative sequenceID=VSP_045319;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
O95197486648159Alternative sequenceID=VSP_047008;Note=In isoform 7. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
O9519748664866Alternative sequenceID=VSP_023759;Note=In isoform 2%2C isoform 3 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10331947,ECO:0000303|PubMed:12811824,ECO:0000303|PubMed:14986
O95197486621032ChainID=PRO_0000168163;Note=Reticulon-3
O9519748662863Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O951976784348843Alternative sequenceID=VSP_045319;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
O951976784348159Alternative sequenceID=VSP_047008;Note=In isoform 7. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
O951976784367843Alternative sequenceID=VSP_023760;Note=In isoform 3%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10331947,ECO:0000303|PubMed:12811824,ECO:0000303|PubMed:14702
O951976784321032ChainID=PRO_0000168163;Note=Reticulon-3
O9519767843229229Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843243243Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9ES97
O9519767843246246Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843283283Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6RJR6
O9519767843316316Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843453453Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843649649Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
O9519767843650650Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
O9519767843735735Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9ES97
O9519767843501501Natural variantID=VAR_057713;Note=D->H;Dbxref=dbSNP:rs7936660
O95197678432863Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255

check button Lost protein functional features of individual exon skipping events in MSBB.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O95197486648843Alternative sequenceID=VSP_045319;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
O95197486648159Alternative sequenceID=VSP_047008;Note=In isoform 7. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
O9519748664866Alternative sequenceID=VSP_023759;Note=In isoform 2%2C isoform 3 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10331947,ECO:0000303|PubMed:12811824,ECO:0000303|PubMed:14986
O95197486621032ChainID=PRO_0000168163;Note=Reticulon-3
O9519748662863Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O951976784348843Alternative sequenceID=VSP_045319;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
O951976784348159Alternative sequenceID=VSP_047008;Note=In isoform 7. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
O951976784367843Alternative sequenceID=VSP_023760;Note=In isoform 3%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10331947,ECO:0000303|PubMed:12811824,ECO:0000303|PubMed:14702
O951976784321032ChainID=PRO_0000168163;Note=Reticulon-3
O9519767843229229Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843243243Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9ES97
O9519767843246246Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843283283Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6RJR6
O9519767843316316Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843453453Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843649649Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
O9519767843650650Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
O9519767843735735Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9ES97
O9519767843501501Natural variantID=VAR_057713;Note=D->H;Dbxref=dbSNP:rs7936660
O95197678432863Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255

check button Lost protein functional features of individual exon skipping events in Mayo.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O95197486648843Alternative sequenceID=VSP_045319;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
O95197486648159Alternative sequenceID=VSP_047008;Note=In isoform 7. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
O9519748664866Alternative sequenceID=VSP_023759;Note=In isoform 2%2C isoform 3 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10331947,ECO:0000303|PubMed:12811824,ECO:0000303|PubMed:14986
O95197486621032ChainID=PRO_0000168163;Note=Reticulon-3
O9519748662863Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O951976784348843Alternative sequenceID=VSP_045319;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
O951976784348159Alternative sequenceID=VSP_047008;Note=In isoform 7. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
O951976784367843Alternative sequenceID=VSP_023760;Note=In isoform 3%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10331947,ECO:0000303|PubMed:12811824,ECO:0000303|PubMed:14702
O951976784321032ChainID=PRO_0000168163;Note=Reticulon-3
O9519767843229229Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843243243Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9ES97
O9519767843246246Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843283283Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6RJR6
O9519767843316316Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843453453Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
O9519767843649649Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
O9519767843650650Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
O9519767843735735Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9ES97
O9519767843501501Natural variantID=VAR_057713;Note=D->H;Dbxref=dbSNP:rs7936660
O95197678432863Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255


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3'-UTR located exon skipping events that lost miRNA binding sites in RTN3

check button 3'-UTR exon skipping evnets lost miRNA binding.
Tissue typeENSTExon skip startExon skip endmicroRNABinding site by TargetScanBinding type by TargetScanBdinding site by miRandaScore of miRandaEnergy by miRanda

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SNVs in the skipped exons for RTN3

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Depth of Coverage in the skipped exon of the mutated samples.

check button - Sashimi plot in the skipped exon of the mutated samples.

check button - Non-synonymous mutations located in the skipped exons.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

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AD stage-associated exon skippint events for RTN3

check button Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR).
AD stage infoCohortTissueSE idCoefficient P-valueChromosomeStrandE1 startE1 endSkipped startSkipped endE2 startE2 end
ADstageMSBBIFGexon_skip_32816-3.740026e-014.992285e-02chr11+637536816375370863756112637561706375815663758421
CDRMSBBIFGexon_skip_2694714.414395e-011.869158e-02chr11+636815736368177863720850637210326374999163750198
CDRMSBBSTGexon_skip_207991-3.387609e-018.953760e-04chr11+636815736368177863718702637210326374999163750198

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for RTN3

check button sQTL information located at the skipped exons.
Tissue typeExon skip IDSNP idLocationP-valueFDR

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Correlation with RNA binding proteins (RBPs) for RTN3

check button Correlated RBP and related information.
Tissue typeRBP nameExon skip IDCorrelation coeifficientP-value
CBTIA1exon_skip_898644.888531e-016.244899e-11
CBTARDBPexon_skip_2255735.133544e-012.163232e-11
CBRBFOX2exon_skip_2255734.507434e-018.002701e-09
CBZNF326exon_skip_2255734.788417e-016.524704e-10
CBELAVL1exon_skip_2255734.473021e-011.071344e-08
CBSAMD4Aexon_skip_2255735.839233e-015.437846e-15
CBCNOT4exon_skip_2255735.275818e-014.735110e-12
CBMATR3exon_skip_2255734.612732e-013.211738e-09
CBRC3H1exon_skip_2255734.469442e-011.104142e-08
CBG3BP2exon_skip_2255734.362988e-012.665166e-08
CBQKIexon_skip_2255734.227772e-017.820552e-08
CBSF1exon_skip_2255734.025285e-013.598398e-07
CBFUBP1exon_skip_2255734.348803e-012.990419e-08
CBKHSRPexon_skip_2255734.340175e-013.206557e-08
CBPUM1exon_skip_2255734.140968e-011.523199e-07
CBHNRNPA2B1exon_skip_2255735.051125e-015.053187e-11
CBCELF1exon_skip_2255734.178085e-011.148040e-07
CBSRSF1exon_skip_2255735.016686e-017.155462e-11
CBRBM41exon_skip_2255735.089257e-013.422311e-11
CBHNRNPFexon_skip_2255734.555272e-015.306007e-09
CBRBM6exon_skip_8534-5.789801e-011.305265e-15
CBRBM3exon_skip_85345.481940e-017.468684e-14
CBPCBP1exon_skip_8534-4.235234e-012.661897e-08
DLPFCELAVL4exon_skip_1603757.094974e-011.690486e-38
DLPFCTIA1exon_skip_1603754.615158e-013.199539e-14
DLPFCPUF60exon_skip_1603755.961663e-018.917816e-25
DLPFCRALYLexon_skip_1603756.582318e-011.484941e-31
DLPFCPTBP3exon_skip_1603755.323690e-013.463292e-19
DLPFCEWSR1exon_skip_1603755.574229e-013.069562e-21
DLPFCDAZAP1exon_skip_265377-6.467080e-012.612477e-32
DLPFCTARDBPexon_skip_265377-4.684781e-011.209982e-15
DLPFCSRSF2exon_skip_265377-5.488918e-016.147346e-22
DLPFCMSI1exon_skip_265377-5.473778e-018.381115e-22
DLPFCPABPN1exon_skip_265377-6.497947e-011.063676e-32
DLPFCELAVL4exon_skip_265377-4.542144e-011.086844e-14
DLPFCRBM25exon_skip_265377-6.255054e-019.556307e-30
DLPFCZNF326exon_skip_265377-4.673552e-011.443628e-15
DLPFCELAVL1exon_skip_265377-4.216516e-011.129261e-12
DLPFCSFPQexon_skip_265377-5.621288e-013.821151e-23
DLPFCRBM6exon_skip_265377-6.076084e-019.896786e-28
DLPFCSRSF11exon_skip_265377-5.658661e-011.704845e-23
DLPFCU2AF2exon_skip_265377-5.811400e-015.648921e-25
DLPFCRBM5exon_skip_265377-5.855033e-012.064597e-25
DLPFCRBM3exon_skip_265377-5.063597e-012.109351e-18
DLPFCMATR3exon_skip_265377-4.208923e-011.251100e-12
DLPFCTRNAU1APexon_skip_265377-6.289062e-013.823505e-30
DLPFCPCBP1exon_skip_265377-5.073707e-011.760920e-18
DLPFCILF2exon_skip_265377-4.665087e-011.648431e-15
DLPFCHNRNPKexon_skip_265377-4.031327e-011.278473e-11
DLPFCPCBP4exon_skip_265377-6.561378e-011.623590e-33
DLPFCUNKexon_skip_265377-5.493292e-015.619171e-22
DLPFCTRA2Aexon_skip_265377-5.015151e-014.969379e-18
DLPFCPCBP2exon_skip_265377-4.318625e-012.776451e-13
DLPFCSNRPAexon_skip_265377-6.437955e-016.041730e-32
DLPFCSF1exon_skip_265377-5.647979e-012.149426e-23
DLPFCKHDRBS3exon_skip_265377-4.795993e-012.032391e-16
DLPFCHNRNPA1exon_skip_265377-4.511590e-011.716619e-14
DLPFCRBM24exon_skip_265377-4.353171e-011.708688e-13
DLPFCFUBP3exon_skip_265377-4.277744e-014.896626e-13
DLPFCFUBP1exon_skip_265377-5.421529e-012.413455e-21
DLPFCKHSRPexon_skip_265377-5.601261e-015.864133e-23
DLPFCHNRNPA0exon_skip_265377-5.174828e-012.798809e-19
DLPFCHNRNPA1L2exon_skip_265377-5.637536e-012.693732e-23
DLPFCHNRNPA2B1exon_skip_265377-4.440512e-014.884906e-14
DLPFCHNRNPDLexon_skip_265377-5.036219e-013.429176e-18
DLPFCRBM45exon_skip_265377-4.300428e-013.577511e-13
DLPFCPUF60exon_skip_265377-6.147110e-011.626095e-28
DLPFCHNRNPABexon_skip_265377-5.063929e-012.096911e-18
DLPFCHNRNPDexon_skip_265377-5.539398e-012.162250e-22
DLPFCNUP42exon_skip_265377-4.790380e-012.227346e-16
DLPFCRALYLexon_skip_265377-4.444385e-014.617225e-14
DLPFCPTBP1exon_skip_265377-5.787257e-019.795644e-25
DLPFCHNRNPLexon_skip_265377-5.837612e-013.091344e-25
DLPFCPABPC3exon_skip_265377-4.005783e-011.766171e-11
DLPFCCELF1exon_skip_265377-6.120378e-013.226096e-28
DLPFCRBM23exon_skip_265377-4.822780e-011.309642e-16
DLPFCPABPC1exon_skip_265377-5.126067e-016.846334e-19
DLPFCPABPC4exon_skip_265377-5.701411e-016.687541e-24
DLPFCEWSR1exon_skip_265377-6.129582e-012.550102e-28
DLPFCSRSF1exon_skip_265377-4.359243e-011.568060e-13
DLPFCSRSF4exon_skip_265377-5.867283e-011.552118e-25
DLPFCSRSF9exon_skip_265377-5.644235e-012.330820e-23
DLPFCSRSF5exon_skip_265377-5.528777e-012.697906e-22
DLPFCHNRNPH2exon_skip_265377-4.105242e-014.940843e-12
DLPFCYBX2exon_skip_265377-5.982053e-011.009354e-26
DLPFCESRP1exon_skip_265377-4.464011e-013.466355e-14
DLPFCZCRB1exon_skip_265377-5.599838e-016.044597e-23
DLPFCHNRNPFexon_skip_265377-4.069202e-017.877534e-12
DLPFCSART3exon_skip_265377-5.890877e-018.928502e-26
DLPFCNOVA1exon_skip_265377-5.587384e-017.876940e-23
HCCRBMS2exon_skip_89864-5.721531e-014.740866e-25
HCCTIA1exon_skip_89864-4.470915e-019.004020e-15
HCCTRNAU1APexon_skip_89864-4.019542e-015.520427e-12
HCCFUBP1exon_skip_89864-4.290928e-011.306168e-13
IFGELAVL4exon_skip_2255734.974765e-018.284434e-03
IFGSRSF2exon_skip_41244-4.446158e-012.014474e-02
IFGILF2exon_skip_41244-5.345793e-014.070538e-03
IFGZCRB1exon_skip_41244-4.436978e-012.043443e-02
PCCRBMS2exon_skip_177360-4.595868e-011.399391e-12
PCCELAVL4exon_skip_1773605.634403e-012.514164e-19
PCCRALYLexon_skip_1773604.624221e-019.784847e-13
PCCRBM3exon_skip_111918-4.120812e-012.611505e-09
PGELAVL4exon_skip_1773604.074476e-012.125335e-09
STGELAVL4exon_skip_898645.060151e-012.288801e-07
STGPUF60exon_skip_898644.092989e-014.627096e-05
STGRALYLexon_skip_898644.971535e-013.994218e-07
STGSFPQexon_skip_2255734.118365e-013.592373e-04
STGTIA1exon_skip_2255734.219274e-012.475170e-04
STGRBM24exon_skip_2255734.327908e-011.635628e-04
STGRBM45exon_skip_2255734.392338e-011.270793e-04
TCRBFOX2exon_skip_2335217.369997e-012.847752e-26
TCELAVL4exon_skip_2335216.850362e-011.491481e-21
TCCNOT4exon_skip_2335214.040118e-014.258956e-07
TCMATR3exon_skip_2335215.684915e-017.164868e-14
TCG3BP2exon_skip_2335216.351840e-017.259851e-18
TCKHDRBS2exon_skip_2335216.611022e-011.075154e-19
TCKHDRBS3exon_skip_2335215.834859e-011.086302e-14
TCRBM24exon_skip_2335215.396471e-012.088327e-12
TCHNRNPA0exon_skip_2335215.496727e-016.708002e-13
TCPUM1exon_skip_2335216.228496e-014.700346e-17
TCHNRNPDexon_skip_2335215.018221e-011.099598e-10
TCNUP42exon_skip_2335215.340481e-013.874570e-12
TCRALYLexon_skip_2335216.092171e-013.372428e-16
TCPTBP3exon_skip_2335215.640123e-011.235919e-13
TCCELF1exon_skip_2335215.029241e-019.863222e-11
TCCPEB1exon_skip_2335214.393006e-012.904390e-08
TCHNRNPH2exon_skip_2335215.662080e-019.470370e-14
TCESRP1exon_skip_2335214.716640e-011.863307e-09
TCNOVA1exon_skip_2335214.434467e-012.075355e-08

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RelatedDrugs for RTN3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RTN3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource