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Center for Computational Systems Medicine

DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenSeurat RData after Anno

GSE140440

DU145 and PC cell linesCell lineProstate cancerProstate cancerChemotherapydocetaxel

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GSE186960

Panc1 cell lineCell linePancreatic cancerPancreatic ductal adenocarcinoma (PDAC)Chemotherapygemcitabine

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GSE138267

CDXTumor tissueLung cancerSmall cell lung cancer (SCLC)ChemotherapyNA

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GSE131984_Pac

SUM159 cell lineCell lineBreast cancerTriple-negative breast cancer (TNBC)Chemotherapypaclitaxel

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GSE163836

FCIBC02 cell lineCell lineBreast cancerInflammatory breast cancerChemotherapypaclitaxel

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GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)Chemotherapypaclitaxel

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GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Chemotherapypaclitaxel

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GSE153697

patientsBone marrow aspirateAcute lymphoblastic leukemiaRelapsed B-cell acute lymphoblastic leukemia (B-ALL)Immunotherapyanti-CD19 CAR-T

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GSE169246_PacAteBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxel

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GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxel

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GSE197268_Axi-cel

patientsPeripheral blood mononuclear cellsAcute lymphoblastic leukemiaLarge B-cell acute lymphoblastic leukemia (B-ALL)Immunotherapyaxi-cel (CAR-T)

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GSE164551

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)ImmunotherapyCAR-T

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PMID34715028

patientsTumor tissueKidney cancerClear cell renal cell carcinoma (ccRCC)Immunotherapynivolumab

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GSE164237

patientsPeripheral blood mononuclear cellsMelanomaAdvanced stages of melanoma Immunotherapypembrolizumab

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GSE212217

patientsPeripheral blood mononuclear cellsEndometrial cancerEpigenetic MMRd endometrial carcinomaImmunotherapypembrolizumab

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GSE150930

patientsPeripheral blood mononuclear cellsChronic lymphocytic leukemiaMucosa-assisted lymphoid tissue (MALT) lymphomaImmunotherapyrituximab + cyclophosphamide + fludarabine

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GSE207422_Sin

patientsTumor tissueLung cancerEGFR/ALK mutation negative non-small cell lung cancer (NSCLC)Immunotherapysintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)

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GSE197268_Tisa-cel

patientsPeripheral blood mononuclear cellsAcute lymphoblastic leukemiaLarge B-cell acute lymphoblastic leukemia (B-ALL)Immunotherapytisa-cel (CAR-T)

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GSE207422_Tor

patientsTumor tissueLung cancerEGFR/ALK mutation negative non-small cell lung cancer (NSCLC)Immunotherapytoripalimab + carboplatin + (docetaxel or pemetrexed or emcitabine)

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GSE189460

patientsBone marrow aspirateMultiple myelomaMultiple myeloma (MM)Targeted therapybortezomib + melphalan + prednisolone

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GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasone

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GSE139386

H3122 cell lineCell lineLung cancerEML4-ALK fusion-positive non-small cell lung cancer (NSCLC)Targeted therapyceritinib

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GSE161195

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapyDARA-KRD (daratumumab + carfilzomib + lenalidomide + dexamethasone)

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GSE158457

PDX cellsCell lineAcute lymphoblastic leukemiaT-cell acute lymphoblastic leukemia (ALL)Targeted therapydasatinib

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GSE168668

LNCaP cell lineCell lineProstate cancerProstate cancerTargeted therapyenzalutamide

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GSE149214

PC9 cell lineCell lineLung cancerEGFR-mutated non-small cell lung cancer (NSCLC)Targeted therapyerlotinib

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GSE162117

patientsPeripheral blood mononuclear cellsAcute myeloid leukemiaTefractory acute myeloid leukemia (AML)Targeted therapyficlatuzumab

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GSE199333

patientsBone marrow aspirateAcute myeloid leukemiaPrimary FLT3-ITD-mutated acute myeloid leukemia (AML)Targeted therapygilteritinib

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GSE111014

patientsPeripheral blood mononuclear cellsChronic lymphocytic leukemiaChronic lymphocytic leukemia (CLL)Targeted therapyibrutinib

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GSE152469

patientsPeripheral blood mononuclear cellsChronic lymphocytic leukemiaChronic lymphocytic leukemia (CLL)Targeted therapyibrutinib

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GSE131984_JQ1

SUM159 cell lineCell lineBreast cancerTriple-negative breast cancer (TNBC)Targeted therapyJQ1

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GSE131984_JQ1Pac

SUM159 cell lineCell lineBreast cancerTriple-negative breast cancer (TNBC)Targeted therapyJQ1 + paclitaxel

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GSE131984_JQ1Pal

SUM159 cell lineCell lineBreast cancerTriple-negative breast cancer (TNBC)Targeted therapyJQ1 + palbociclib

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GSE104987

MCF7 cell lineCell lineBreast cancerER+ breast cancerTargeted therapyKDM5-C70

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GSE131984_Pal

SUM159 cell lineCell lineBreast cancerTriple-negative breast cancer (TNBC)Targeted therapypalbociclib

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GSE108397

451Lu cell lineCell lineMelanomaMelanomaTargeted therapyPLX-4720

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GSE161801_IMiD

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapypomalidomide + dexamethasone OR lenalidomide + dexamethasone

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GSE175716

PDXTumor tissueLiver cancerAdvanced hepatocellular carcinomaTargeted therapysorafenib

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GSE115251

Kelly cell lineCell lineNeuroblastomaNeuroblastomaTargeted therapyTAE684

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GSE164897_Vem

A375 cell lineCell lineMelanomaBRAFV600E-mutant melanomaTargeted therapyvemurafenib

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GSE164897_VemCob

A375 cell lineCell lineMelanomaBRAFV600E-mutant melanomaTargeted therapyvemurafenib + combimetinib

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GSE164897_VemTra

A375 cell lineCell lineMelanomaB+E2:E57RAFV600E-mutant melanomaTargeted therapyvemurafenib + trametinib

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