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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: ZNF763

Summary for ZNF763

Gene informationGene symbol

ZNF763

Ensembl ID

ENSG00000197054

Entrez ID

284390

Gene namezinc finger protein 763
SynonymsZNF440L
Gene typeprotein_coding
UniProtAcc

NA


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Dataset with differentially expressed gene: ZNF763

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE140440

DU145 and PC cell linesCell lineProstate cancerProstate cancerChemotherapydocetaxelNAMalignant cells-0.4686664.93e-02

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Expression of ZNF763 in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to ZNF763

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF763

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
ZNF763hsa-miR-188-3p99.9995NM_001012753
ZNF763hsa-miR-6833-3p99.818NM_001012753
ZNF763hsa-miR-4768-5p99.6734NM_001012753
ZNF763hsa-miR-612699.6194NM_001012753
ZNF763hsa-miR-3925-3p99.4824NM_001012753
ZNF763hsa-miR-3156-3p99.232NM_001012753
ZNF763hsa-miR-1260a99.232NM_001012753
ZNF763hsa-miR-1260b99.232NM_001012753
ZNF763hsa-miR-199a-5p98.7583NM_001012753
ZNF763hsa-miR-6873-3p98.1234NM_001012753
ZNF763hsa-miR-199b-5p98.0157NM_001012753
ZNF763hsa-miR-7154-5p97.9108NM_001012753
ZNF763hsa-miR-449397.1215NM_001012753
ZNF763hsa-miR-605-3p97.1215NM_001012753
ZNF763hsa-miR-6809-3p95.4724NM_001012753
ZNF763hsa-miR-550a-3p94.7796NM_001012753
ZNF763hsa-miR-433-3p94.1877NM_001012753
ZNF763hsa-miR-200c-5p93.0295NM_001012753
ZNF763hsa-miR-200b-5p92.5279NM_001012753
ZNF763hsa-miR-200a-5p92.5279NM_001012753
ZNF763hsa-miR-6845-3p89.4103NM_001012753
ZNF763hsa-miR-296-3p88.5193NM_001012753
ZNF763hsa-miR-182587.6553NM_001012753
ZNF763hsa-miR-430285.8813NM_001012753
ZNF763hsa-miR-766-3p85.3931NM_001012753
ZNF763hsa-miR-182784.9853NM_001012753
ZNF763hsa-miR-203a-3p82.5562NM_001012753
ZNF763hsa-miR-6516-3p82.0642NM_001012753
ZNF763hsa-miR-6768-3p80.4565NM_001012753
ZNF763hsa-miR-431680.2304NM_001012753
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Motifs and transcription factors (TFs) regulating ZNF763

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."