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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZNF736

Summary for ZNF736

Gene information	Gene symbol	ZNF736
	Ensembl ID	ENSG00000234444
	Entrez ID	728927
	Gene name	zinc finger protein 736
	Synonyms	NA
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: ZNF736

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-2.1681	1.77e-10

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Expression of ZNF736 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZNF736

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF736

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZNF736	hsa-miR-340-5p	97.4256	NM_001170905
ZNF736	hsa-miR-8485	94.3601	NM_001294255
ZNF736	hsa-miR-142-5p	92.6486	NM_001170905
ZNF736	hsa-miR-5590-3p	92.6486	NM_001170905
ZNF736	hsa-miR-5091	92.3559	NM_001170905
ZNF736	hsa-miR-1302	92.352	NM_001294255
ZNF736	hsa-miR-4298	92.352	NM_001294255
ZNF736	hsa-miR-513a-3p	90.3487	NM_001170905
ZNF736	hsa-miR-513c-3p	90.3487	NM_001170905
ZNF736	hsa-miR-20b-3p	90.1237	NM_001170905
ZNF736	hsa-miR-186-5p	89.4415	NM_001170905
ZNF736	hsa-miR-372-5p	88.4202	NM_001170905
ZNF736	hsa-miR-3189-3p	88.0727	NM_001170905
ZNF736	hsa-miR-3646	87.5558	NM_001170905
ZNF736	hsa-miR-10397-5p	87.3526	NM_001294255
ZNF736	hsa-miR-4282	87.1632	NM_001170905
ZNF736	hsa-miR-6835-3p	87.0568	NM_001170905
ZNF736	hsa-miR-5692a	86.7774	NM_001170905
ZNF736	hsa-miR-892b	86.0525	NM_001170905
ZNF736	hsa-miR-6882-5p	85.8639	NM_001170905
ZNF736	hsa-miR-5582-3p	85.6045	NM_001170905
ZNF736	hsa-miR-3606-3p	85.3885	NM_001170905
ZNF736	hsa-miR-513b-5p	85.0505	NM_001294255
ZNF736	hsa-miR-373-5p	85.042	NM_001170905
ZNF736	hsa-miR-616-5p	85.042	NM_001170905
ZNF736	hsa-miR-371b-5p	85.042	NM_001170905
ZNF736	hsa-miR-137-3p	84.1886	NM_001294255
ZNF736	hsa-miR-1537-5p	84.1576	NM_001294255
ZNF736	hsa-miR-217-5p	82.9969	NM_001170905
ZNF736	hsa-miR-568	81.8478	NM_001170905
ZNF736	hsa-miR-4698	81.6036	NM_001170905
ZNF736	hsa-miR-16-1-3p	80.0041	NM_001170905

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Motifs and transcription factors (TFs) regulating ZNF736

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."