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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZNF600

Summary for ZNF600

Gene information	Gene symbol	ZNF600
	Ensembl ID	ENSG00000189190
	Entrez ID	162966
	Gene name	zinc finger protein 600
	Synonyms	DKFZp686F06123\|KR-ZNF1
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: ZNF600

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-1.53401	9.08e-06

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Expression of ZNF600 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZNF600

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF600

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZNF600	hsa-miR-3064-3p	99.6956	NM_001321866
ZNF600	hsa-miR-373-5p	97.4454	NM_198457
ZNF600	hsa-miR-371b-5p	97.4454	NM_198457
ZNF600	hsa-miR-616-5p	97.4454	NM_198457
ZNF600	hsa-miR-6832-3p	95.6373	NM_198457
ZNF600	hsa-miR-19a-5p	95.1104	NM_198457
ZNF600	hsa-miR-19b-2-5p	95.1104	NM_198457
ZNF600	hsa-miR-19b-1-5p	95.1104	NM_198457
ZNF600	hsa-miR-548av-5p	93.4652	NM_198457
ZNF600	hsa-miR-548k	93.4652	NM_198457
ZNF600	hsa-miR-8054	93.4652	NM_198457
ZNF600	hsa-miR-664a-3p	93.1816	NM_198457
ZNF600	hsa-miR-1915-5p	91.2054	NM_001321866
ZNF600	hsa-miR-4685-3p	90.8879	NM_198457
ZNF600	hsa-miR-4287	90.8879	NM_198457
ZNF600	hsa-miR-4776-3p	90.367	NM_001321866
ZNF600	hsa-miR-5787	88.1514	NM_198457
ZNF600	hsa-miR-4505	88.1514	NM_198457
ZNF600	hsa-miR-3925-3p	88.058	NM_198457
ZNF600	hsa-miR-3121-3p	87.8472	NM_198457
ZNF600	hsa-miR-3613-3p	86.4672	NM_198457
ZNF600	hsa-miR-4715-3p	85.6179	NM_001321866
ZNF600	hsa-miR-12121	85.6179	NM_001321866
ZNF600	hsa-miR-6833-3p	83.6744	NM_198457
ZNF600	hsa-miR-106a-3p	81.9371	NM_198457
ZNF600	hsa-miR-4768-5p	81.2164	NM_198457

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Motifs and transcription factors (TFs) regulating ZNF600

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."