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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZNF587

Summary for ZNF587

Gene information	Gene symbol	ZNF587
	Ensembl ID	ENSG00000198466
	Entrez ID	84914
	Gene name	zinc finger protein 587
	Synonyms	FLJ14710\|FLJ20813\|UBF-fl\|ZF6
	Gene type	protein_coding
	UniProtAcc	Q96SQ5

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Dataset with differentially expressed gene: ZNF587

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE168668	LNCaP cell line	Cell line	Prostate cancer	Prostate cancer	Targeted therapy	enzalutamide	NA	Malignant cells	-0.281963	0.00e+00

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Expression of ZNF587 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZNF587

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF587

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZNF587	hsa-miR-371b-5p	97.1386	NM_001204817
ZNF587	hsa-miR-373-5p	97.1386	NM_001204817
ZNF587	hsa-miR-616-5p	97.1386	NM_001204817
ZNF587	hsa-miR-3613-3p	94.5946	NM_001204817
ZNF587	hsa-miR-4291	93.3926	NM_001204817
ZNF587	hsa-miR-4433a-3p	91.2008	NM_001204817
ZNF587	hsa-miR-12132	90.6216	NM_001204817
ZNF587	hsa-miR-6885-3p	88.1855	NM_001204817
ZNF587	hsa-miR-1827	87.2382	NM_001204817
ZNF587	hsa-miR-4531	86.5868	NM_001204817
ZNF587	hsa-let-7c-3p	86.3993	NM_001204817
ZNF587	hsa-miR-340-5p	84.9988	NM_001204817
ZNF587	hsa-miR-7160-5p	84.9887	NM_001204817
ZNF587	hsa-miR-4500	83.3798	NM_001204817
ZNF587	hsa-miR-4649-3p	82.998	NM_001204817
ZNF587	hsa-miR-142-5p	82.8501	NM_001204817
ZNF587	hsa-miR-383-3p	82.7379	NM_001204817
ZNF587	hsa-miR-5590-3p	82.5004	NM_001204817
ZNF587	hsa-miR-6745	81.9931	NM_001204817
ZNF587	hsa-miR-1273h-5p	81.3207	NM_001204817
ZNF587	hsa-miR-4478	80.9832	NM_001204817
ZNF587	hsa-miR-7977	80.7108	NM_001204817
ZNF587	hsa-miR-6779-5p	80.4886	NM_001204817
ZNF587	hsa-miR-4537	80.0435	NM_001204817

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Motifs and transcription factors (TFs) regulating ZNF587

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."