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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZNF544

Summary for ZNF544

Gene information	Gene symbol	ZNF544
	Ensembl ID	ENSG00000198131
	Entrez ID	27300
	Gene name	zinc finger protein 544
	Synonyms	AF020591
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: ZNF544

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-1.28572	2.12e-08

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Expression of ZNF544 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZNF544

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF544

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZNF544	hsa-miR-3925-3p	99.9992	NM_001320786
ZNF544	hsa-miR-188-3p	99.6765	NM_001320786
ZNF544	hsa-miR-6852-3p	98.5368	NM_001320786
ZNF544	hsa-miR-4728-5p	97.5971	NM_001320776
ZNF544	hsa-miR-6780a-5p	97.3052	NM_001320776
ZNF544	hsa-miR-3692-3p	97.2928	NM_001320786
ZNF544	hsa-miR-6799-5p	96.0888	NM_001320776
ZNF544	hsa-miR-3909	95.8686	NM_001320786
ZNF544	hsa-miR-3689b-3p	95.7523	NM_001320776
ZNF544	hsa-miR-3689c	95.7523	NM_001320776
ZNF544	hsa-miR-3689a-3p	95.7523	NM_001320776
ZNF544	hsa-miR-30b-3p	95.7523	NM_001320776
ZNF544	hsa-miR-1273h-5p	95.7523	NM_001320776
ZNF544	hsa-miR-6779-5p	95.7523	NM_001320776
ZNF544	hsa-miR-6785-5p	95.143	NM_001320776
ZNF544	hsa-miR-199b-5p	94.033	NM_001320786
ZNF544	hsa-miR-199a-5p	94.033	NM_001320786
ZNF544	hsa-miR-185-3p	93.9251	NM_001320782
ZNF544	hsa-miR-4262	93.9226	NM_001320786
ZNF544	hsa-miR-7106-5p	93.1818	NM_001320776
ZNF544	hsa-miR-149-3p	92.9825	NM_001320776
ZNF544	hsa-miR-766-3p	92.9293	NM_001320786
ZNF544	hsa-miR-4668-5p	91.9591	NM_001320780
ZNF544	hsa-miR-6883-5p	91.6513	NM_001320776
ZNF544	hsa-miR-10393-5p	91.3217	NM_001320786
ZNF544	hsa-miR-7703	91.1393	NM_001320786
ZNF544	hsa-miR-6833-3p	90.8669	NM_001320786
ZNF544	hsa-miR-4502	90.5457	NM_001320789
ZNF544	hsa-miR-4768-5p	89.7497	NM_001320786
ZNF544	hsa-miR-1825	89.1317	NM_001320786
ZNF544	hsa-miR-4302	88.144	NM_001320786
ZNF544	hsa-miR-6815-3p	88.086	NM_001320786
ZNF544	hsa-miR-4794	87.1292	NM_001320786
ZNF544	hsa-miR-136-5p	86.6164	NM_001320780
ZNF544	hsa-miR-3921	86.5721	NM_001320789
ZNF544	hsa-miR-4653-5p	86.5721	NM_001320789
ZNF544	hsa-miR-330-5p	86.4748	NM_001320786
ZNF544	hsa-miR-3064-5p	86.2556	NM_001320786
ZNF544	hsa-miR-3085-3p	86.2556	NM_001320786
ZNF544	hsa-miR-6504-5p	86.2556	NM_001320786
ZNF544	hsa-miR-204-3p	85.9323	NM_001320780
ZNF544	hsa-miR-4646-5p	85.9323	NM_001320780
ZNF544	hsa-miR-664a-5p	85.8904	NM_001320786
ZNF544	hsa-miR-642b-5p	85.8411	NM_001320789
ZNF544	hsa-miR-4420	85.707	NM_001320789
ZNF544	hsa-miR-181b-3p	85.707	NM_001320789
ZNF544	hsa-miR-181b-2-3p	85.707	NM_001320789
ZNF544	hsa-miR-12123	85.1837	NM_001320789
ZNF544	hsa-miR-181d-5p	84.7649	NM_001320786
ZNF544	hsa-miR-181a-5p	84.7649	NM_001320786

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Motifs and transcription factors (TFs) regulating ZNF544

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."