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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: ZNF37A

Summary for ZNF37A

Gene informationGene symbol

ZNF37A

Ensembl ID

ENSG00000075407

Entrez ID

7587

Gene namezinc finger protein 37A
SynonymsKOX21|ZNF37
Gene typeprotein_coding
UniProtAcc

NA


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Dataset with differentially expressed gene: ZNF37A

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE140440

DU145 and PC cell linesCell lineProstate cancerProstate cancerChemotherapydocetaxelNAMalignant cells-1.253924.59e-04

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Expression of ZNF37A in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to ZNF37A

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF37A

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
ZNF37Ahsa-miR-426299.9905NM_001324259
ZNF37Ahsa-miR-3692-3p99.9792NM_001324259
ZNF37Ahsa-miR-181c-5p99.9768NM_001324259
ZNF37Ahsa-miR-181b-5p99.9768NM_001324259
ZNF37Ahsa-miR-181a-5p99.9768NM_001324259
ZNF37Ahsa-miR-181d-5p99.9768NM_001324259
ZNF37Ahsa-miR-188-3p99.9411NM_001324259
ZNF37Ahsa-miR-629-3p99.8536NM_001324259
ZNF37Ahsa-miR-5011-5p98.9409NM_001324252
ZNF37Ahsa-miR-4743-3p98.6903NM_001324259
ZNF37Ahsa-miR-450298.1358NM_001324259
ZNF37Ahsa-miR-6867-5p96.7553NM_001324259
ZNF37Ahsa-miR-607496.6692NM_001324260
ZNF37Ahsa-miR-329-5p94.7513NM_001324259
ZNF37Ahsa-miR-4713-5p94.7176NM_001324259
ZNF37Ahsa-miR-1260a94.4439NM_001324259
ZNF37Ahsa-miR-1260b94.4439NM_001324259
ZNF37Ahsa-miR-190a-3p94.2641NM_001324252
ZNF37Ahsa-miR-6888-3p94.2321NM_001324259
ZNF37Ahsa-miR-3156-3p93.8918NM_001324259
ZNF37Ahsa-miR-26b-3p93.7046NM_001007094
ZNF37Ahsa-miR-4446-5p93.3609NM_001324259
ZNF37Ahsa-miR-495-5p93.3568NM_001007094
ZNF37Ahsa-miR-877-3p92.5963NM_001324260
ZNF37Ahsa-miR-181b-2-3p92.2259NM_001324260
ZNF37Ahsa-miR-181b-3p92.2259NM_001324260
ZNF37Ahsa-miR-442092.085NM_001324260
ZNF37Ahsa-miR-10395-3p92.0223NM_001324260
ZNF37Ahsa-miR-10393-5p91.7543NM_001324260
ZNF37Ahsa-miR-807591.7031NM_001324259
ZNF37Ahsa-miR-211791.4861NM_001324259
ZNF37Ahsa-miR-365990.7655NM_001324252
ZNF37Ahsa-miR-337-3p90.6265NM_001007094
ZNF37Ahsa-miR-430689.1941NM_001007094
ZNF37Ahsa-miR-6810-3p89.1752NM_001324259
ZNF37Ahsa-miR-4684-3p89.0038NM_001324258
ZNF37Ahsa-miR-126788.7843NM_001324259
ZNF37Ahsa-miR-6867-3p88.6953NM_001324259
ZNF37Ahsa-miR-3127-5p88.6597NM_001007094
ZNF37Ahsa-miR-146a-3p87.8125NM_001324260
ZNF37Ahsa-miR-316387.4999NM_001324252
ZNF37Ahsa-miR-4680-3p87.2858NM_001324260
ZNF37Ahsa-miR-6770-5p86.2768NM_001324259
ZNF37Ahsa-miR-1225-5p85.5476NM_001324252
ZNF37Ahsa-miR-146b-3p85.0062NM_001324259
ZNF37Ahsa-miR-7844-5p84.9632NM_001007094
ZNF37Ahsa-miR-3152-3p84.9NM_001324258
ZNF37Ahsa-miR-548aw84.5485NM_001324258
ZNF37Ahsa-miR-6759-5p84.4101NM_001007094
ZNF37Ahsa-miR-452884.2843NM_001324260
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Motifs and transcription factors (TFs) regulating ZNF37A

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."