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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZNF264

Summary for ZNF264

Gene information	Gene symbol	ZNF264
	Ensembl ID	ENSG00000083844
	Entrez ID	9422
	Gene name	zinc finger protein 264
	Synonyms	KIAA0412
	Gene type	protein_coding
	UniProtAcc	O43296

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Dataset with differentially expressed gene: ZNF264

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE169246_PacAteTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	Mast cells	-0.652537	1.41e-02

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Expression of ZNF264 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZNF264

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF264

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZNF264	hsa-miR-5011-5p	98.7913	NM_003417
ZNF264	hsa-miR-548c-3p	97.6535	NM_003417
ZNF264	hsa-miR-190a-3p	97.1391	NM_003417
ZNF264	hsa-miR-6867-5p	97.0646	NM_003417
ZNF264	hsa-miR-371b-5p	95.6149	NM_003417
ZNF264	hsa-miR-373-5p	95.6149	NM_003417
ZNF264	hsa-miR-616-5p	95.6149	NM_003417
ZNF264	hsa-miR-95-5p	95.1288	NM_003417
ZNF264	hsa-miR-1200	94.5229	NM_003417
ZNF264	hsa-miR-4463	94.2871	NM_003417
ZNF264	hsa-miR-4293	93.4104	NM_003417
ZNF264	hsa-miR-3613-3p	92.8005	NM_003417
ZNF264	hsa-miR-8485	91.2398	NM_003417
ZNF264	hsa-miR-548ar-3p	90.0752	NM_003417
ZNF264	hsa-miR-944	88.9759	NM_003417
ZNF264	hsa-miR-371a-5p	88.8381	NM_003417
ZNF264	hsa-miR-20a-5p	88.1131	NM_003417
ZNF264	hsa-miR-106b-5p	88.1131	NM_003417
ZNF264	hsa-miR-7-1-3p	87.9391	NM_003417
ZNF264	hsa-miR-7-2-3p	87.9391	NM_003417
ZNF264	hsa-miR-548a-3p	87.7543	NM_003417
ZNF264	hsa-miR-548bc	87.7268	NM_003417
ZNF264	hsa-miR-548az-3p	87.7268	NM_003417
ZNF264	hsa-miR-548e-3p	87.7268	NM_003417
ZNF264	hsa-miR-548f-3p	87.7268	NM_003417
ZNF264	hsa-miR-450a-1-3p	87.544	NM_003417
ZNF264	hsa-miR-1252-5p	87.53	NM_003417
ZNF264	hsa-miR-4324	87.2205	NM_003417
ZNF264	hsa-miR-5688	87.068	NM_003417
ZNF264	hsa-miR-4534	86.8955	NM_003417
ZNF264	hsa-miR-877-5p	86.6544	NM_003417
ZNF264	hsa-miR-106a-5p	86.5675	NM_003417
ZNF264	hsa-miR-20b-5p	86.4911	NM_003417
ZNF264	hsa-miR-519d-3p	86.4911	NM_003417
ZNF264	hsa-miR-17-5p	86.4911	NM_003417
ZNF264	hsa-miR-93-5p	86.4911	NM_003417
ZNF264	hsa-miR-526b-3p	86.223	NM_003417
ZNF264	hsa-miR-6778-3p	85.6614	NM_003417
ZNF264	hsa-miR-361-3p	85.6553	NM_003417
ZNF264	hsa-miR-495-3p	85.6303	NM_003417
ZNF264	hsa-miR-197-3p	84.0979	NM_003417
ZNF264	hsa-miR-4703-5p	84.0039	NM_003417
ZNF264	hsa-miR-4482-3p	83.3992	NM_003417
ZNF264	hsa-miR-1245b-3p	83.3342	NM_003417
ZNF264	hsa-miR-548x-3p	83.2366	NM_003417
ZNF264	hsa-miR-548aj-3p	83.2366	NM_003417
ZNF264	hsa-miR-3194-3p	82.9669	NM_003417
ZNF264	hsa-miR-544b	82.4358	NM_003417
ZNF264	hsa-miR-3125	82.4157	NM_003417
ZNF264	hsa-miR-4724-5p	82.3855	NM_003417

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Motifs and transcription factors (TFs) regulating ZNF264

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ZNF264	transfac_pro__M05838	ZNF550 (directAnnotation).
ZNF264	taipale_cyt_meth__KLF12_NGCCGACGCCCW_FL_meth_repr	KLF12 (directAnnotation).
ZNF264	metacluster_113.4	MYB; MYB; MYBL1; MYBL2 (directAnnotation). MYB; MYB; MYBL1; MYBL2 (inferredBy_Orthology).
ZNF264	dbtfbs__ZNF577_HEK293_ENCSR776MDR_Rep2_N1	ZNF577 (directAnnotation).
ZNF264	taipale_tf_pairs__ETV2_RFX5_NACTTCCGGYNNNNGCAACSN_CAP_repr	ETV2; RFX5 (directAnnotation).
ZNF264	transfac_pro__M04944	GABPA (directAnnotation).
ZNF264	transfac_pro__M06383	ZNF629 (inferredBy_Orthology).
ZNF264	jaspar__MA1994.1	NKX2-1 (inferredBy_Orthology).
ZNF264	transfac_pro__M06856	ZNF611 (directAnnotation).
ZNF264	transfac_pro__M05883	ZNF709 (directAnnotation).
ZNF264	cisbp__M08198	ELF1 (directAnnotation).
ZNF264	transfac_pro__M04861	SIX5 (directAnnotation).
ZNF264	transfac_pro__M06279	ZNF124 (directAnnotation).
ZNF264	kznf__ZNF649_Imbeault2017_RP_RCADE	ZNF649 (directAnnotation).
ZNF264	transfac_pro__M06394	ZNF761 (directAnnotation).
ZNF264	transfac_pro__M06594	ZNF668 (directAnnotation).
ZNF264	transfac_pro__M06111	ZNF254 (directAnnotation).
ZNF264	transfac_pro__M06451	ZNF614 (directAnnotation).
ZNF264	taipale_tf_pairs__ELK1_TBX21_TNRCACCGGAAGNN_CAP_repr	ELK1; TBX21 (directAnnotation).
ZNF264	transfac_pro__M06745	ZNF780B (directAnnotation).
ZNF264	metacluster_126.11	ZNF286A (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."