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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZNF124

Summary for ZNF124

Gene information	Gene symbol	ZNF124
	Ensembl ID	ENSG00000196418
	Entrez ID	7678
	Gene name	zinc finger protein 124
	Synonyms	HZF-16\|HZF16
	Gene type	protein_coding
	UniProtAcc	Q15973

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Dataset with differentially expressed gene: ZNF124

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-1.12218	3.47e-02

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Expression of ZNF124 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZNF124

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF124

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZNF124	hsa-miR-3925-3p	99.9905	NM_001297569
ZNF124	hsa-miR-5011-5p	99.5527	NM_001297567
ZNF124	hsa-miR-4795-5p	99.111	NM_001243740
ZNF124	hsa-miR-6833-3p	98.7529	NM_001297569
ZNF124	hsa-miR-188-3p	98.7482	NM_001297569
ZNF124	hsa-miR-190a-3p	98.4326	NM_001297567
ZNF124	hsa-miR-4768-5p	98.1589	NM_001297569
ZNF124	hsa-miR-4463	97.7203	NM_001297567
ZNF124	hsa-miR-4262	97.4713	NM_001297569
ZNF124	hsa-miR-605-3p	96.2144	NM_001297569
ZNF124	hsa-miR-587	96.1635	NM_003431
ZNF124	hsa-miR-3132	95.9877	NM_003431
ZNF124	hsa-miR-181c-5p	94.4016	NM_001297569
ZNF124	hsa-miR-181b-5p	94.4016	NM_001297569
ZNF124	hsa-miR-181d-5p	94.4016	NM_001297569
ZNF124	hsa-miR-181a-5p	94.4016	NM_001297569
ZNF124	hsa-miR-3064-3p	93.811	NM_001297569
ZNF124	hsa-miR-197-5p	92.9912	NM_003431
ZNF124	hsa-miR-4790-3p	92.4356	NM_001243740
ZNF124	hsa-miR-539-3p	91.813	NM_001243740
ZNF124	hsa-miR-485-3p	91.813	NM_001243740
ZNF124	hsa-miR-517-5p	91.7577	NM_003431
ZNF124	hsa-miR-6815-5p	91.7417	NM_001243740
ZNF124	hsa-miR-6865-5p	91.7417	NM_001243740
ZNF124	hsa-miR-378a-3p	91.5825	NM_001297567
ZNF124	hsa-miR-378i	91.5825	NM_001297567
ZNF124	hsa-miR-422a	91.5825	NM_001297567
ZNF124	hsa-miR-378c	91.5825	NM_001297567
ZNF124	hsa-miR-378e	91.5825	NM_001297567
ZNF124	hsa-miR-378h	91.5825	NM_001297567
ZNF124	hsa-miR-378d	91.5825	NM_001297567
ZNF124	hsa-miR-378b	91.5825	NM_001297567
ZNF124	hsa-miR-378f	91.5825	NM_001297567
ZNF124	hsa-miR-153-5p	90.8141	NM_001243740
ZNF124	hsa-miR-6516-3p	90.2756	NM_001297569
ZNF124	hsa-miR-6126	89.7253	NM_001297569
ZNF124	hsa-miR-3681-5p	89.594	NM_001243740
ZNF124	hsa-miR-6849-5p	89.594	NM_001243740
ZNF124	hsa-miR-6845-3p	89.4308	NM_001297569
ZNF124	hsa-miR-3613-3p	89.3466	NM_003431
ZNF124	hsa-miR-4477b	88.7539	NM_003431
ZNF124	hsa-miR-1298-3p	88.573	NM_003431
ZNF124	hsa-miR-6873-3p	88.3567	NM_001297569
ZNF124	hsa-miR-6074	88.0773	NM_003431
ZNF124	hsa-miR-766-3p	87.7844	NM_001297569
ZNF124	hsa-miR-4709-5p	87.7559	NM_001243740
ZNF124	hsa-miR-6768-5p	87.7043	NM_001243740
ZNF124	hsa-miR-6759-3p	87.1065	NM_003431
ZNF124	hsa-miR-1245b-3p	86.3228	NM_001243740
ZNF124	hsa-miR-4314	86.1881	NM_003431

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Motifs and transcription factors (TFs) regulating ZNF124

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."