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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZMYM4

Summary for ZMYM4

Gene information	Gene symbol	ZMYM4
	Ensembl ID	ENSG00000146463
	Entrez ID	9202
	Gene name	zinc finger MYM-type containing 4
	Synonyms	KIAA0425\|MYM\|ZNF198L3\|ZNF262
	Gene type	protein_coding
	UniProtAcc	Q5VZL5

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Dataset with differentially expressed gene: ZMYM4

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE186960	Panc1 cell line	Cell line	Pancreatic cancer	Pancreatic ductal adenocarcinoma (PDAC)	Chemotherapy	gemcitabine	NA	Malignant cells	0.253187	6.57e-14

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Expression of ZMYM4 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZMYM4

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZMYM4

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZMYM4	hsa-miR-335-3p	99.8926	NM_005095
ZMYM4	hsa-let-7a-3p	96.7269	NM_005095
ZMYM4	hsa-let-7f-1-3p	96.7269	NM_005095
ZMYM4	hsa-let-7b-3p	96.7269	NM_005095
ZMYM4	hsa-miR-98-3p	96.7269	NM_005095
ZMYM4	hsa-miR-3133	95.7752	NM_005095
ZMYM4	hsa-miR-4797-3p	94.7361	NM_005095
ZMYM4	hsa-miR-4668-5p	94.3116	NM_005095
ZMYM4	hsa-miR-3148	94.2323	NM_005095
ZMYM4	hsa-miR-450a-1-3p	93.9907	NM_005095
ZMYM4	hsa-miR-34c-5p	93.0717	NM_005095
ZMYM4	hsa-miR-449b-5p	93.0717	NM_005095
ZMYM4	hsa-miR-449a	93.0231	NM_005095
ZMYM4	hsa-miR-34a-5p	93.0231	NM_005095
ZMYM4	hsa-miR-9985	91.0048	NM_005095
ZMYM4	hsa-miR-27a-3p	91.0048	NM_005095
ZMYM4	hsa-miR-27b-3p	91.0048	NM_005095
ZMYM4	hsa-miR-224-5p	90.6679	NM_005095
ZMYM4	hsa-miR-6890-3p	90.179	NM_005095
ZMYM4	hsa-miR-6809-3p	90.1176	NM_005095
ZMYM4	hsa-miR-6800-3p	88.7343	NM_005095
ZMYM4	hsa-miR-4743-3p	87.415	NM_005095
ZMYM4	hsa-miR-331-3p	87.3265	NM_005095
ZMYM4	hsa-miR-6783-5p	86.717	NM_005095
ZMYM4	hsa-miR-3646	84.885	NM_005095
ZMYM4	hsa-miR-9902	84.1603	NM_005095
ZMYM4	hsa-miR-4446-5p	84.0375	NM_005095
ZMYM4	hsa-miR-4727-3p	83.8589	NM_005095
ZMYM4	hsa-miR-2110	83.7965	NM_005095
ZMYM4	hsa-miR-7151-3p	83.4547	NM_005095
ZMYM4	hsa-miR-4729	82.7789	NM_005095
ZMYM4	hsa-miR-4521	82.0072	NM_005095
ZMYM4	hsa-miR-6830-3p	81.7245	NM_005095
ZMYM4	hsa-miR-551b-5p	81.7057	NM_005095
ZMYM4	hsa-miR-496	81.4334	NM_005095
ZMYM4	hsa-miR-664b-3p	80.9129	NM_005095
ZMYM4	hsa-miR-579-3p	80.9129	NM_005095
ZMYM4	hsa-miR-3974	80.7915	NM_005095

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Motifs and transcription factors (TFs) regulating ZMYM4

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ZMYM4	metacluster_144.8	ZNF30; ZNF30 (directAnnotation).
ZMYM4	dbtfbs__GMEB1_K562_ENCSR928KOR_merged_N1	GMEB1 (directAnnotation).
ZMYM4	transfac_pro__M04918	EGR1 (directAnnotation).
ZMYM4	metacluster_7.5	PLAGL1; PLAGL1 (directAnnotation).
ZMYM4	metacluster_7.13	ZFX (directAnnotation).
ZMYM4	metacluster_144.3	ZNF704; ZNF704 (directAnnotation).
ZMYM4	tfdimers__MD00154	MZF1; SREBF1 (directAnnotation).
ZMYM4	kznf__ZNF384_Schmitges2016_RCADE	ZNF384 (directAnnotation).
ZMYM4	kznf__ZNF730_Imbeault2017_RP_RCADE	ZNF730 (directAnnotation).
ZMYM4	transfac_pro__M01219	SP1 (directAnnotation). SP3 (inferredBy_Orthology).
ZMYM4	metacluster_155.23	BCL11B; ZNF711; ZNF711 (directAnnotation). ZFY (inferredBy_Orthology).
ZMYM4	cisbp__M00249	WT1 (directAnnotation).
ZMYM4	cisbp__M01863	ZNF711 (inferredBy_Orthology).
ZMYM4	taipale_tf_pairs__GCM1_ELF1_GTGCGGGCGGAAGTN_CAP_repr	ELF1; GCM1 (directAnnotation).
ZMYM4	homer__GGCGGGAARN_E2F6	E2F6 (directAnnotation).
ZMYM4	taipale_cyt_meth__ZNF460_NRMCGCCCCCCGN_eDBD_meth	ZNF460 (directAnnotation).
ZMYM4	kznf__ZNF571_Imbeault2017_OM_RCADE	ZNF571 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."