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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: WDR33

Summary for WDR33

Gene information	Gene symbol	WDR33
	Ensembl ID	ENSG00000136709
	Entrez ID	55339
	Gene name	WD repeat domain 33
	Synonyms	FLJ11294\|NET14\|WDC146
	Gene type	protein_coding
	UniProtAcc	Q9C0J8

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Dataset with differentially expressed gene: WDR33

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE163836	FCIBC02 cell line	Cell line	Breast cancer	Inflammatory breast cancer	Chemotherapy	paclitaxel	NA	Malignant cells	-0.271343	2.10e-44

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Expression of WDR33 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to WDR33

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating WDR33

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
WDR33	hsa-miR-6809-3p	97.2665	NM_018383
WDR33	hsa-miR-338-5p	97.2231	NM_001006623
WDR33	hsa-miR-548e-5p	96.4942	NM_001006623
WDR33	hsa-miR-6867-5p	94.8275	NM_001006623
WDR33	hsa-miR-580-3p	94.7497	NM_001006623
WDR33	hsa-miR-6773-3p	93.9533	NM_018383
WDR33	hsa-miR-141-3p	93.8861	NM_001006622
WDR33	hsa-miR-4760-3p	93.6236	NM_001006622
WDR33	hsa-miR-8081	93.3372	NM_001006623
WDR33	hsa-miR-4743-3p	93.084	NM_018383
WDR33	hsa-miR-200a-3p	92.9251	NM_001006622
WDR33	hsa-miR-576-5p	92.253	NM_001006623
WDR33	hsa-miR-1468-3p	91.595	NM_001006623
WDR33	hsa-miR-937-5p	91.5847	NM_001006623
WDR33	hsa-miR-6876-5p	91.0757	NM_001006622
WDR33	hsa-miR-4476	91.0757	NM_001006622
WDR33	hsa-miR-4518	90.9708	NM_018383
WDR33	hsa-miR-1266-5p	90.9514	NM_018383
WDR33	hsa-miR-3658	90.4439	NM_001006623
WDR33	hsa-miR-4435	90.0884	NM_001006623
WDR33	hsa-miR-21-3p	89.2487	NM_001006623
WDR33	hsa-miR-122b-3p	89.2487	NM_001006623
WDR33	hsa-miR-7154-5p	89.1867	NM_018383
WDR33	hsa-miR-223-5p	88.7777	NM_001006622
WDR33	hsa-miR-6515-3p	88.5403	NM_018383
WDR33	hsa-miR-542-3p	88.5273	NM_018383
WDR33	hsa-miR-130a-3p	88.448	NM_001006623
WDR33	hsa-miR-323b-3p	87.9004	NM_001006623
WDR33	hsa-miR-4639-3p	87.03	NM_018383
WDR33	hsa-miR-4762-5p	86.8969	NM_001006623
WDR33	hsa-miR-493-5p	86.597	NM_001006623
WDR33	hsa-miR-4425	86.3255	NM_001006622
WDR33	hsa-miR-6851-5p	85.9229	NM_001006622
WDR33	hsa-miR-3689d	85.9229	NM_001006622
WDR33	hsa-miR-6878-5p	85.8926	NM_001006623
WDR33	hsa-miR-301a-5p	85.6858	NM_018383
WDR33	hsa-miR-301b-5p	85.6858	NM_018383
WDR33	hsa-miR-493-3p	84.9773	NM_001006623
WDR33	hsa-miR-6833-3p	84.7198	NM_018383
WDR33	hsa-miR-4295	84.6906	NM_001006623
WDR33	hsa-miR-130b-3p	84.6906	NM_001006623
WDR33	hsa-miR-454-3p	84.6906	NM_001006623
WDR33	hsa-miR-301b-3p	84.6906	NM_001006623
WDR33	hsa-miR-3666	84.6906	NM_001006623
WDR33	hsa-miR-301a-3p	84.6906	NM_001006623
WDR33	hsa-miR-548an	84.2452	NM_001006623
WDR33	hsa-miR-3065-5p	83.9971	NM_001006622
WDR33	hsa-miR-6842-5p	83.9745	NM_018383
WDR33	hsa-miR-7110-5p	83.9745	NM_018383
WDR33	hsa-miR-1279	83.6189	NM_001006622

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Motifs and transcription factors (TFs) regulating WDR33

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
WDR33	dbtfbs__GMEB1_K562_ENCSR928KOR_merged_N1	GMEB1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."