Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: VCPIP1

Summary for VCPIP1

Gene information	Gene symbol	VCPIP1
	Ensembl ID	ENSG00000175073
	Entrez ID	80124
	Gene name	valosin containing protein interacting protein 1
	Synonyms	DUBA3\|FLJ23132\|KIAA1850\|VCIP135
	Gene type	protein_coding
	UniProtAcc	Q96JH7

Top

Dataset with differentially expressed gene: VCPIP1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.511036	0.00e+00

Top

Expression of VCPIP1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to VCPIP1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating VCPIP1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
VCPIP1	hsa-miR-548c-3p	99.3925	NM_025054
VCPIP1	hsa-miR-4282	98.6629	NM_025054
VCPIP1	hsa-miR-5197-5p	96.8616	NM_025054
VCPIP1	hsa-miR-126-5p	96.0288	NM_025054
VCPIP1	hsa-miR-544a	95.2906	NM_025054
VCPIP1	hsa-miR-513c-5p	94.8155	NM_025054
VCPIP1	hsa-miR-514b-5p	94.8155	NM_025054
VCPIP1	hsa-miR-5000-5p	94.7683	NM_025054
VCPIP1	hsa-miR-5582-3p	94.4364	NM_025054
VCPIP1	hsa-miR-4795-3p	93.041	NM_025054
VCPIP1	hsa-miR-4735-5p	92.5169	NM_025054
VCPIP1	hsa-miR-24-3p	92.3917	NM_025054
VCPIP1	hsa-miR-5001-3p	92.3333	NM_025054
VCPIP1	hsa-miR-4261	91.4072	NM_025054
VCPIP1	hsa-miR-548aj-3p	90.9653	NM_025054
VCPIP1	hsa-miR-548x-3p	90.9653	NM_025054
VCPIP1	hsa-miR-6760-5p	90.807	NM_025054
VCPIP1	hsa-miR-4756-3p	90.6499	NM_025054
VCPIP1	hsa-miR-2276-3p	90.5111	NM_025054
VCPIP1	hsa-miR-8087	90.4367	NM_025054
VCPIP1	hsa-miR-3123	89.7616	NM_025054
VCPIP1	hsa-miR-548ah-3p	89.525	NM_025054
VCPIP1	hsa-miR-548aq-3p	89.525	NM_025054
VCPIP1	hsa-miR-548am-3p	89.525	NM_025054
VCPIP1	hsa-miR-548j-3p	89.525	NM_025054
VCPIP1	hsa-miR-548ae-3p	89.525	NM_025054
VCPIP1	hsa-miR-140-5p	89.0956	NM_025054
VCPIP1	hsa-miR-548z	88.8518	NM_025054
VCPIP1	hsa-miR-548ac	88.8518	NM_025054
VCPIP1	hsa-miR-548h-3p	88.8518	NM_025054
VCPIP1	hsa-miR-499a-5p	88.7076	NM_025054
VCPIP1	hsa-miR-4427	88.6678	NM_025054
VCPIP1	hsa-miR-7856-5p	88.2997	NM_025054
VCPIP1	hsa-miR-4799-5p	88.221	NM_025054
VCPIP1	hsa-miR-616-5p	87.9361	NM_025054
VCPIP1	hsa-miR-373-5p	87.9361	NM_025054
VCPIP1	hsa-miR-371b-5p	87.9361	NM_025054
VCPIP1	hsa-miR-548d-3p	87.8585	NM_025054
VCPIP1	hsa-miR-548bb-3p	87.8585	NM_025054
VCPIP1	hsa-miR-545-3p	87.7091	NM_025054
VCPIP1	hsa-miR-6887-3p	87.4701	NM_025054
VCPIP1	hsa-miR-381-3p	87.2873	NM_025054
VCPIP1	hsa-miR-300	87.2873	NM_025054
VCPIP1	hsa-miR-147b-5p	86.9613	NM_025054
VCPIP1	hsa-miR-4744	86.3653	NM_025054
VCPIP1	hsa-miR-8076	86.1417	NM_025054
VCPIP1	hsa-miR-183-3p	85.5409	NM_025054
VCPIP1	hsa-miR-3942-3p	85.3989	NM_025054
VCPIP1	hsa-miR-494-3p	85.202	NM_025054
VCPIP1	hsa-miR-6835-3p	85.0956	NM_025054

Page: 1 2

Top

Motifs and transcription factors (TFs) regulating VCPIP1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."