Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: TRIP11

Summary for TRIP11

Gene information	Gene symbol	TRIP11
	Ensembl ID	ENSG00000100815
	Entrez ID	9321
	Gene name	thyroid hormone receptor interactor 11
	Synonyms	CEV14\|GMAP-210\|GMAP210\|Trip230
	Gene type	protein_coding
	UniProtAcc	Q15643

Top

Dataset with differentially expressed gene: TRIP11

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.706165	0.00e+00

Top

Expression of TRIP11 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to TRIP11

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating TRIP11

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
TRIP11	hsa-miR-153-5p	99.8666	NM_001321851
TRIP11	hsa-miR-4422	98.8527	NM_001321851
TRIP11	hsa-miR-539-5p	97.7474	NM_001321851
TRIP11	hsa-miR-1250-3p	97.6209	NM_001321851
TRIP11	hsa-miR-3919	97.5292	NM_001321851
TRIP11	hsa-miR-548e-5p	97.2448	NM_001321851
TRIP11	hsa-miR-5688	96.7583	NM_001321851
TRIP11	hsa-miR-495-3p	96.5728	NM_001321851
TRIP11	hsa-miR-548c-3p	96.5063	NM_001321851
TRIP11	hsa-miR-4717-5p	96.1215	NM_001321851
TRIP11	hsa-miR-106b-5p	95.1627	NM_001321851
TRIP11	hsa-miR-20a-5p	95.1627	NM_001321851
TRIP11	hsa-miR-4255	94.3804	NM_001321851
TRIP11	hsa-miR-93-5p	94.0095	NM_001321851
TRIP11	hsa-miR-106a-5p	94.0095	NM_001321851
TRIP11	hsa-miR-20b-5p	94.0095	NM_001321851
TRIP11	hsa-miR-526b-3p	94.0095	NM_001321851
TRIP11	hsa-miR-519d-3p	94.0095	NM_001321851
TRIP11	hsa-miR-17-5p	94.0095	NM_001321851
TRIP11	hsa-miR-302e	93.1935	NM_001321851
TRIP11	hsa-miR-520a-3p	92.0055	NM_001321851
TRIP11	hsa-miR-520e-3p	92.0055	NM_001321851
TRIP11	hsa-miR-372-3p	92.0055	NM_001321851
TRIP11	hsa-miR-373-3p	92.0055	NM_001321851
TRIP11	hsa-miR-520d-3p	92.0055	NM_001321851
TRIP11	hsa-miR-520c-3p	92.0055	NM_001321851
TRIP11	hsa-miR-520b-3p	92.0055	NM_001321851
TRIP11	hsa-miR-302d-3p	92.0055	NM_001321851
TRIP11	hsa-miR-302c-3p	92.0055	NM_001321851
TRIP11	hsa-miR-302b-3p	92.0055	NM_001321851
TRIP11	hsa-miR-302a-3p	92.0055	NM_001321851
TRIP11	hsa-miR-607	91.7893	NM_001321851
TRIP11	hsa-miR-4753-5p	89.5079	NM_001321851
TRIP11	hsa-miR-4742-3p	89.2435	NM_001321851
TRIP11	hsa-miR-548k	88.4412	NM_001321851
TRIP11	hsa-miR-548av-5p	88.4412	NM_001321851
TRIP11	hsa-miR-662	87.7007	NM_001321851
TRIP11	hsa-miR-12124	87.6794	NM_001321851
TRIP11	hsa-miR-520d-5p	87.6483	NM_001321851
TRIP11	hsa-miR-524-5p	87.6483	NM_001321851
TRIP11	hsa-miR-4793-3p	87.62	NM_001321851
TRIP11	hsa-miR-8054	87.4559	NM_001321851
TRIP11	hsa-miR-576-5p	87.1112	NM_001321851
TRIP11	hsa-miR-3163	87.0987	NM_001321851
TRIP11	hsa-miR-4796-3p	86.0255	NM_001321851
TRIP11	hsa-miR-589-3p	85.8146	NM_001321851
TRIP11	hsa-miR-155-5p	85.4766	NM_001321851
TRIP11	hsa-miR-222-5p	85.3981	NM_001321851
TRIP11	hsa-miR-12136	84.9914	NM_001321851
TRIP11	hsa-miR-3134	84.7947	NM_001321851

Page: 1 2

Top

Motifs and transcription factors (TFs) regulating TRIP11

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."