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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: TAF2

Summary for TAF2

Gene informationGene symbol

TAF2

Ensembl ID

ENSG00000064313

Entrez ID

6873

Gene nameTATA-box binding protein associated factor 2
SynonymsCIF150|TAF2B|TAFII150
Gene typeprotein_coding
UniProtAcc

Q6P1X5


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Dataset with differentially expressed gene: TAF2

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE175716

PDXTumor tissueLiver cancerAdvanced hepatocellular carcinomaTargeted therapysorafenibNAMalignant cells0.3548451.20e-14

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Expression of TAF2 in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to TAF2

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating TAF2

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
TAF2hsa-miR-892c-5p97.4133NM_003184
TAF2hsa-miR-480395.1905NM_003184
TAF2hsa-miR-6835-3p93.8236NM_003184
TAF2hsa-miR-59992.4532NM_003184
TAF2hsa-miR-653-3p91.2254NM_003184
TAF2hsa-miR-651-3p90.5899NM_003184
TAF2hsa-miR-6867-5p89.9966NM_003184
TAF2hsa-miR-374c-5p89.3976NM_003184
TAF2hsa-miR-655-3p89.3976NM_003184
TAF2hsa-miR-5580-3p88.6167NM_003184
TAF2hsa-miR-129788.0541NM_003184
TAF2hsa-miR-5582-3p88.0199NM_003184
TAF2hsa-miR-548l87.9803NM_003184
TAF2hsa-miR-105-5p87.9016NM_003184
TAF2hsa-miR-7853-5p87.9016NM_003184
TAF2hsa-miR-548n87.3781NM_003184
TAF2hsa-miR-5692a86.5568NM_003184
TAF2hsa-miR-472186.0005NM_003184
TAF2hsa-miR-5681a84.5755NM_003184
TAF2hsa-miR-1213684.4662NM_003184
TAF2hsa-miR-6832-3p84.4317NM_003184
TAF2hsa-miR-302a-5p84.3041NM_003184
TAF2hsa-miR-26a-5p84.0312NM_003184
TAF2hsa-miR-26b-5p84.0312NM_003184
TAF2hsa-miR-4797-3p83.7792NM_003184
TAF2hsa-let-7a-3p83.7001NM_003184
TAF2hsa-let-7f-1-3p83.7001NM_003184
TAF2hsa-let-7b-3p83.7001NM_003184
TAF2hsa-miR-98-3p83.7001NM_003184
TAF2hsa-miR-5004-5p83.593NM_003184
TAF2hsa-miR-445581.548NM_003184
TAF2hsa-miR-118381.393NM_003184
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Motifs and transcription factors (TFs) regulating TAF2

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."