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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: SYNJ2BP

Summary for SYNJ2BP

Gene information	Gene symbol	SYNJ2BP
	Ensembl ID	ENSG00000213463
	Entrez ID	55333
	Gene name	synaptojanin 2 binding protein
	Synonyms	Arip2
	Gene type	protein_coding
	UniProtAcc	P57105

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Dataset with differentially expressed gene: SYNJ2BP

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	0.51006	1.36e-03

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Expression of SYNJ2BP in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to SYNJ2BP

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating SYNJ2BP

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
SYNJ2BP	hsa-miR-6768-3p	98.5318	NM_018373
SYNJ2BP	hsa-miR-3120-3p	95.9964	NM_018373
SYNJ2BP	hsa-miR-5680	95.5532	NM_018373
SYNJ2BP	hsa-miR-4711-3p	94.6675	NM_018373
SYNJ2BP	hsa-miR-6783-3p	94.0541	NM_018373
SYNJ2BP	hsa-miR-1343-3p	93.4832	NM_018373
SYNJ2BP	hsa-miR-4753-3p	93.3722	NM_018373
SYNJ2BP	hsa-miR-10527-5p	93.1951	NM_018373
SYNJ2BP	hsa-miR-616-5p	93.017	NM_018373
SYNJ2BP	hsa-miR-373-5p	93.017	NM_018373
SYNJ2BP	hsa-miR-371b-5p	93.017	NM_018373
SYNJ2BP	hsa-miR-5582-5p	91.8549	NM_018373
SYNJ2BP	hsa-miR-509-5p	91.8351	NM_018373
SYNJ2BP	hsa-miR-509-3-5p	91.8351	NM_018373
SYNJ2BP	hsa-miR-4293	91.7062	NM_018373
SYNJ2BP	hsa-miR-4418	91.6687	NM_018373
SYNJ2BP	hsa-miR-548an	90.8716	NM_018373
SYNJ2BP	hsa-miR-4474-5p	90.8692	NM_018373
SYNJ2BP	hsa-miR-548p	90.1362	NM_018373
SYNJ2BP	hsa-miR-6873-3p	89.1775	NM_018373
SYNJ2BP	hsa-miR-627-3p	89.1448	NM_018373
SYNJ2BP	hsa-miR-6073	87.8271	NM_018373
SYNJ2BP	hsa-miR-597-3p	87.7336	NM_018373
SYNJ2BP	hsa-miR-329-5p	87.0202	NM_018373
SYNJ2BP	hsa-miR-6844	86.5277	NM_018373
SYNJ2BP	hsa-miR-6833-3p	86.5081	NM_018373
SYNJ2BP	hsa-miR-4768-5p	86.1878	NM_018373
SYNJ2BP	hsa-miR-6832-3p	85.7074	NM_018373
SYNJ2BP	hsa-miR-5691	85.4646	NM_018373
SYNJ2BP	hsa-miR-6805-3p	85.4646	NM_018373
SYNJ2BP	hsa-miR-371a-5p	85.3914	NM_018373
SYNJ2BP	hsa-miR-3663-5p	84.7137	NM_018373
SYNJ2BP	hsa-miR-12136	84.1131	NM_018373
SYNJ2BP	hsa-miR-4713-5p	83.9796	NM_018373
SYNJ2BP	hsa-miR-3160-5p	83.42	NM_018373
SYNJ2BP	hsa-miR-130a-5p	82.1926	NM_018373
SYNJ2BP	hsa-miR-7151-3p	80.627	NM_018373
SYNJ2BP	hsa-miR-3613-3p	80.6111	NM_018373
SYNJ2BP	hsa-miR-4795-3p	80.5257	NM_018373
SYNJ2BP	hsa-miR-4753-5p	80.5	NM_018373
SYNJ2BP	hsa-miR-32-3p	80.3232	NM_018373

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Motifs and transcription factors (TFs) regulating SYNJ2BP

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."