Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: STMN2

Summary for STMN2

Gene information	Gene symbol	STMN2
	Ensembl ID	ENSG00000104435
	Entrez ID	11075
	Gene name	stathmin 2
	Synonyms	SCG10\|SCGN10
	Gene type	protein_coding
	UniProtAcc	Q93045

Top

Dataset with differentially expressed gene: STMN2

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	-1.31658	0.00e+00

Top

Expression of STMN2 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to STMN2

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating STMN2

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
STMN2	hsa-miR-4760-3p	98.9348	NM_001199214
STMN2	hsa-miR-6769b-5p	98.7298	NM_007029
STMN2	hsa-miR-6769a-5p	97.9871	NM_007029
STMN2	hsa-miR-6808-5p	97.9195	NM_001199214
STMN2	hsa-miR-940	97.9195	NM_001199214
STMN2	hsa-miR-6893-5p	97.9195	NM_001199214
STMN2	hsa-miR-4700-3p	96.6901	NM_007029
STMN2	hsa-miR-664b-3p	91.9799	NM_007029
STMN2	hsa-miR-579-3p	91.9799	NM_007029
STMN2	hsa-miR-4699-3p	91.8815	NM_007029
STMN2	hsa-miR-449c-5p	91.0774	NM_001199214
STMN2	hsa-miR-34b-5p	91.0774	NM_001199214
STMN2	hsa-miR-1178-3p	90.3673	NM_007029
STMN2	hsa-miR-1238-5p	90.3286	NM_007029
STMN2	hsa-miR-4758-5p	90.3286	NM_007029
STMN2	hsa-miR-374a-5p	90.2813	NM_007029
STMN2	hsa-miR-29a-3p	90.0215	NM_001199214
STMN2	hsa-miR-29c-3p	90.0215	NM_001199214
STMN2	hsa-miR-29b-3p	90.0215	NM_001199214
STMN2	hsa-miR-654-5p	89.576	NM_007029
STMN2	hsa-miR-541-3p	89.576	NM_007029
STMN2	hsa-miR-206	89.365	NM_001199214
STMN2	hsa-miR-1-3p	89.365	NM_001199214
STMN2	hsa-miR-544a	88.995	NM_001199214
STMN2	hsa-miR-4259	88.6451	NM_001199214
STMN2	hsa-miR-5584-3p	88.4217	NM_001199214
STMN2	hsa-miR-2682-5p	87.4252	NM_001199214
STMN2	hsa-miR-92a-2-5p	87.1369	NM_007029
STMN2	hsa-miR-767-5p	87.0111	NM_001199214
STMN2	hsa-miR-1323	87.0005	NM_001199214
STMN2	hsa-miR-5682	86.9296	NM_001199214
STMN2	hsa-miR-548av-3p	86.274	NM_001199214
STMN2	hsa-miR-374b-5p	85.9669	NM_007029
STMN2	hsa-miR-613	85.8885	NM_001199214
STMN2	hsa-miR-6511a-5p	85.7354	NM_001199214
STMN2	hsa-miR-1910-3p	85.7354	NM_001199214
STMN2	hsa-miR-4715-5p	85.1969	NM_001199214
STMN2	hsa-miR-6757-3p	84.891	NM_001199214
STMN2	hsa-miR-7844-5p	84.7016	NM_007029
STMN2	hsa-miR-9985	83.8541	NM_001199214
STMN2	hsa-miR-27b-3p	83.8541	NM_001199214
STMN2	hsa-miR-27a-3p	83.8541	NM_001199214
STMN2	hsa-miR-6514-5p	82.1953	NM_007029
STMN2	hsa-miR-548o-3p	81.8903	NM_001199214
STMN2	hsa-miR-302c-5p	81.8028	NM_007029
STMN2	hsa-miR-383-3p	81.7628	NM_007029
STMN2	hsa-miR-122-5p	81.7059	NM_007029

Page: 1

Top

Motifs and transcription factors (TFs) regulating STMN2

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
STMN2	transfac_pro__M02843	BBX (inferredBy_Orthology).

Page: 1

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."