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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: STARD13

Summary for STARD13

Gene information	Gene symbol	STARD13
	Ensembl ID	ENSG00000133121
	Entrez ID	90627
	Gene name	StAR related lipid transfer domain containing 13
	Synonyms	ARHGAP37\|DLC2\|GT650\|LINC00464
	Gene type	protein_coding
	UniProtAcc	Q9Y3M8

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Dataset with differentially expressed gene: STARD13

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE108397	451Lu cell line	Cell line	Melanoma	Melanoma	Targeted therapy	PLX-4720	NA	Malignant cells	0.325014	0.00e+00

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Expression of STARD13 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to STARD13

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating STARD13

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
STARD13	hsa-miR-5011-5p	99.9256	NM_052851
STARD13	hsa-miR-4500	99.8616	NM_052851
STARD13	hsa-miR-202-3p	99.8405	NM_052851
STARD13	hsa-let-7e-5p	99.8294	NM_052851
STARD13	hsa-let-7a-5p	99.8294	NM_052851
STARD13	hsa-let-7i-5p	99.8294	NM_052851
STARD13	hsa-let-7b-5p	99.8294	NM_052851
STARD13	hsa-let-7f-5p	99.8294	NM_052851
STARD13	hsa-let-7c-5p	99.8294	NM_052851
STARD13	hsa-miR-98-5p	99.8294	NM_052851
STARD13	hsa-let-7g-5p	99.8294	NM_052851
STARD13	hsa-miR-4458	99.7399	NM_052851
STARD13	hsa-let-7d-5p	99.7399	NM_052851
STARD13	hsa-miR-4319	99.5301	NM_052851
STARD13	hsa-miR-125b-5p	99.2778	NM_052851
STARD13	hsa-miR-125a-5p	99.2778	NM_052851
STARD13	hsa-miR-8485	99.2686	NM_052851
STARD13	hsa-miR-345-3p	99.2216	NM_052851
STARD13	hsa-miR-670-5p	98.6742	NM_052851
STARD13	hsa-miR-1277-5p	98.5822	NM_052851
STARD13	hsa-miR-410-3p	98.3261	NM_052851
STARD13	hsa-miR-7849-3p	97.8956	NM_052851
STARD13	hsa-miR-4699-3p	97.7437	NM_052851
STARD13	hsa-miR-3163	97.481	NM_052851
STARD13	hsa-miR-9-5p	96.9016	NM_052851
STARD13	hsa-miR-12124	96.8012	NM_052851
STARD13	hsa-miR-4732-3p	95.6214	NM_052851
STARD13	hsa-miR-190a-3p	95.21	NM_052851
STARD13	hsa-let-7f-2-3p	93.9518	NM_052851
STARD13	hsa-miR-1185-2-3p	93.9518	NM_052851
STARD13	hsa-miR-1185-1-3p	93.9518	NM_052851
STARD13	hsa-miR-148b-3p	93.2035	NM_052851
STARD13	hsa-miR-148a-3p	93.2035	NM_052851
STARD13	hsa-miR-152-3p	93.2035	NM_052851
STARD13	hsa-miR-5588-5p	91.3117	NM_052851
STARD13	hsa-miR-4720-5p	91.3117	NM_052851
STARD13	hsa-miR-4799-3p	91.3117	NM_052851
STARD13	hsa-miR-4318	90.9952	NM_052851
STARD13	hsa-miR-5580-3p	90.9631	NM_052851
STARD13	hsa-miR-590-3p	89.5051	NM_052851
STARD13	hsa-miR-4729	87.7964	NM_052851
STARD13	hsa-miR-5692b	87.7349	NM_052851
STARD13	hsa-miR-5692c	87.7349	NM_052851
STARD13	hsa-miR-582-5p	86.9211	NM_052851
STARD13	hsa-miR-4496	86.8302	NM_052851
STARD13	hsa-miR-4789-3p	84.7364	NM_052851
STARD13	hsa-miR-4717-5p	84.6231	NM_052851
STARD13	hsa-miR-3941	84.4409	NM_052851
STARD13	hsa-miR-7853-5p	84.3148	NM_052851
STARD13	hsa-miR-105-5p	84.3148	NM_052851

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Motifs and transcription factors (TFs) regulating STARD13

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
STARD13	taipale_tf_pairs__ETS2_RCCGGAAGTG_HT	ETS2 (directAnnotation).
STARD13	metacluster_166.4	BCLAF1; EHF; ELF1; ELF1; ELF1; ELF1; ELF1; ELF1; ELF2; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK3; ELK3; ELK3; ELK3; ELK4; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS1; ETS1; ETS1; ETV1; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV4; ETV4; ETV4; ETV4; ETV5; ETV7; FEV; FEV; FLI1; FLI1; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; GABPB1; GATAD1; PHF20; ZBTB25; ZBTB40 (directAnnotation). EHF; ELF1; ELF1; ELF3; ELF5; ELK3; ELK4; ERG; ETS1; ETV1; ETV2; ETV4; FLI1; GABPA; GABPA (inferredBy_Orthology).
STARD13	taipale_tf_pairs__MEIS1_ELF1_NTGCCGGAAGTN_CAP_repr	ELF1; MEIS1 (directAnnotation).
STARD13	metacluster_191.3	EHF; ELF1; ELF1; ELF1; ELF4; ELK1; ELK3; ELK3; ELK4; ELK4; ERF; ETS1; ETS2; ETV3; ETV4; ETV5; FEV; FEV; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; SPDEF; ZNF200 (directAnnotation). ELK1; ELK1; ELK3; ELK3; ELK4; ELK4; ETV1; ETV1; ETV4; ETV4; ETV4; ETV5; GABPA; GABPA (inferredBy_Orthology).
STARD13	swissregulon__hs__ELF2	ELF2 (directAnnotation).
STARD13	taipale_tf_pairs__ETV5_HOXA2_RSCGGWAATKR_CAP	ETV5; HOXA2 (directAnnotation).
STARD13	hdpi__ETV4	ETV4 (directAnnotation).
STARD13	taipale_tf_pairs__ETV5_FOXI1_RSCGGATGTTGN_CAP	ETV5; FOXI1 (directAnnotation).
STARD13	taipale_tf_pairs__ELK1_TEF_NSCGGAWNTTACGTAAN_CAP	ELK1; TEF (directAnnotation).
STARD13	taipale_tf_pairs__ETV2_HOXA2_NCCGGAAGTMATTA_CAP_repr	ETV2; HOXA2 (directAnnotation).
STARD13	taipale_tf_pairs__FOXO1_ELK3_RCCGGAWGTKKW_CAP	ELK3; FOXO1 (directAnnotation).
STARD13	taipale_tf_pairs__ETV5_EOMES_TNRCACCGGAWN_CAP	EOMES; ETV5 (directAnnotation).
STARD13	metacluster_166.2	ELK4; ETS1; ETS1; ETV1; ETV3; ETV4; ETV5; ETV7 (directAnnotation). GABPA (inferredBy_Orthology).
STARD13	taipale_tf_pairs__HOXB2_ELK3_RSCGGAAGTMRTTA_CAP	ELK3; HOXB2 (directAnnotation).
STARD13	taipale_tf_pairs__ELK1_HOXA3_RSCGGTAATKR_CAP_repr	ELK1; HOXA3 (directAnnotation).
STARD13	jaspar__MA1483.2	ELF2 (directAnnotation).
STARD13	taipale_tf_pairs__HOXB2_ETV4_ACCGGAAATGAN_CAP	ETV4; HOXB2 (directAnnotation).
STARD13	taipale_tf_pairs__ELF2_NATGCGGAAGTR_HT	ELF2 (directAnnotation).
STARD13	taipale_tf_pairs__ELK1_EOMES_TNRCACCGGAAGN_CAP	ELK1; EOMES (directAnnotation).
STARD13	taipale_tf_pairs__HOXB2_ELF1_SMGGAAGTMRTTA_CAP	ELF1; HOXB2 (directAnnotation).
STARD13	taipale_tf_pairs__ERF_FOXI1_RSCGGATGTTKWN_CAP_repr	ERF; FOXI1 (directAnnotation).
STARD13	taipale_cyt_meth__ZBTB2_NTTTMCGGTWAN_eDBD	ZBTB2 (directAnnotation).
STARD13	metacluster_198.7	AHR; ZBTB14; ZBTB14; ZBTB14 (directAnnotation).
STARD13	taipale_tf_pairs__ERF_HES7_NCCGGAANNNNNNCACGYGNN_CAP_repr	ERF; HES7 (directAnnotation).
STARD13	taipale_tf_pairs__ELK1_FOXI1_RSCGGATGTKKN_CAP	ELK1; FOXI1 (directAnnotation).
STARD13	metacluster_19.7	GMEB1; GMEB2 (inferredBy_Orthology).
STARD13	hdpi__FLI1	FLI1 (directAnnotation).
STARD13	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
STARD13	jaspar__MA1957.1	ELK1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."