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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: SLC9A7

Summary for SLC9A7

Gene information	Gene symbol	SLC9A7
	Ensembl ID	ENSG00000065923
	Entrez ID	84679
	Gene name	solute carrier family 9 member A7
	Synonyms	NHE-7\|NHE7
	Gene type	protein_coding
	UniProtAcc	Q96T83

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Dataset with differentially expressed gene: SLC9A7

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	pDCs	0.413805	2.41e-03

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Expression of SLC9A7 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to SLC9A7

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating SLC9A7

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
SLC9A7	hsa-miR-3613-3p	98.675	NM_001257291
SLC9A7	hsa-miR-4775	91.7214	NM_001257291
SLC9A7	hsa-miR-92b-3p	90.1061	NM_001257291
SLC9A7	hsa-miR-32-5p	90.1061	NM_001257291
SLC9A7	hsa-miR-92a-3p	90.1061	NM_001257291
SLC9A7	hsa-miR-20a-3p	89.275	NM_001257291
SLC9A7	hsa-miR-410-3p	88.5707	NM_001257291
SLC9A7	hsa-miR-363-3p	87.7258	NM_001257291
SLC9A7	hsa-miR-367-3p	87.7258	NM_001257291
SLC9A7	hsa-miR-25-3p	87.7258	NM_001257291
SLC9A7	hsa-miR-4716-5p	87.0741	NM_001257291
SLC9A7	hsa-miR-3665	87.0246	NM_001257291
SLC9A7	hsa-miR-371b-5p	86.8087	NM_001257291
SLC9A7	hsa-miR-488-3p	86.2286	NM_001257291
SLC9A7	hsa-miR-335-3p	86.0325	NM_001257291
SLC9A7	hsa-miR-5197-3p	85.7101	NM_001257291
SLC9A7	hsa-miR-6516-5p	85.5966	NM_001257291
SLC9A7	hsa-miR-320a-5p	85.2477	NM_001257291
SLC9A7	hsa-miR-129-5p	84.7254	NM_001257291
SLC9A7	hsa-miR-590-3p	84.5023	NM_001257291
SLC9A7	hsa-miR-4714-3p	83.9859	NM_001257291
SLC9A7	hsa-miR-9983-3p	83.8086	NM_001257291
SLC9A7	hsa-miR-373-5p	83.7391	NM_001257291
SLC9A7	hsa-miR-616-5p	83.7391	NM_001257291
SLC9A7	hsa-miR-509-3-5p	83.2817	NM_001257291
SLC9A7	hsa-miR-509-5p	83.2817	NM_001257291
SLC9A7	hsa-miR-27a-3p	82.3704	NM_001257291
SLC9A7	hsa-miR-9985	82.3704	NM_001257291
SLC9A7	hsa-miR-27b-3p	82.3704	NM_001257291
SLC9A7	hsa-miR-125a-3p	81.5737	NM_001257291
SLC9A7	hsa-miR-5581-3p	81.3283	NM_001257291
SLC9A7	hsa-miR-4470	80.8266	NM_001257291
SLC9A7	hsa-miR-3935	80.2699	NM_001257291
SLC9A7	hsa-miR-4418	80.0653	NM_001257291

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Motifs and transcription factors (TFs) regulating SLC9A7

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."