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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: SLC35G1

Summary for SLC35G1

Gene information	Gene symbol	SLC35G1
	Ensembl ID	ENSG00000176273
	Entrez ID	159371
	Gene name	solute carrier family 35 member G1
	Synonyms	C10orf60\|FLJ33990\|TMEM20
	Gene type	protein_coding
	UniProtAcc	Q2M3R5

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Dataset with differentially expressed gene: SLC35G1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE207422_Tor	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	toripalimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	Malignant cells	-0.885652	0.00e+00

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Expression of SLC35G1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to SLC35G1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating SLC35G1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
SLC35G1	hsa-miR-1303	97.988	NM_153226
SLC35G1	hsa-miR-506-3p	96.0281	NM_001134658
SLC35G1	hsa-miR-124-3p	95.7376	NM_001134658
SLC35G1	hsa-miR-182-5p	95.5137	NM_001134658
SLC35G1	hsa-miR-5582-5p	94.0174	NM_001134658
SLC35G1	hsa-miR-4324	93.8743	NM_001134658
SLC35G1	hsa-miR-1200	92.798	NM_001134658
SLC35G1	hsa-miR-4714-3p	92.4075	NM_153226
SLC35G1	hsa-miR-4310	92.3502	NM_001134658
SLC35G1	hsa-miR-4642	92.0426	NM_001134658
SLC35G1	hsa-miR-4263	91.2939	NM_153226
SLC35G1	hsa-miR-3121-3p	90.7452	NM_153226
SLC35G1	hsa-miR-4789-3p	90.3239	NM_153226
SLC35G1	hsa-miR-4729	89.0333	NM_153226
SLC35G1	hsa-miR-7157-5p	88.5919	NM_001134658
SLC35G1	hsa-miR-138-2-3p	88.1453	NM_153226
SLC35G1	hsa-miR-548c-3p	87.5763	NM_153226
SLC35G1	hsa-miR-4524a-5p	86.6601	NM_001134658
SLC35G1	hsa-miR-4524b-5p	86.6601	NM_001134658
SLC35G1	hsa-miR-3662	86.0524	NM_153226
SLC35G1	hsa-miR-15b-5p	85.9371	NM_001134658
SLC35G1	hsa-miR-195-5p	85.9371	NM_001134658
SLC35G1	hsa-miR-15a-5p	85.9371	NM_001134658
SLC35G1	hsa-miR-16-5p	85.9371	NM_001134658
SLC35G1	hsa-miR-1-3p	85.9224	NM_153226
SLC35G1	hsa-miR-206	85.9224	NM_153226
SLC35G1	hsa-miR-8062	85.4088	NM_153226
SLC35G1	hsa-miR-5004-5p	85.3955	NM_153226
SLC35G1	hsa-miR-3123	85.2667	NM_153226
SLC35G1	hsa-miR-500b-5p	85.2543	NM_153226
SLC35G1	hsa-miR-362-5p	85.2543	NM_153226
SLC35G1	hsa-miR-4251	85.0168	NM_001134658
SLC35G1	hsa-miR-613	84.4226	NM_153226
SLC35G1	hsa-miR-5696	83.2564	NM_153226
SLC35G1	hsa-miR-3613-3p	81.8957	NM_153226
SLC35G1	hsa-miR-424-5p	81.4129	NM_001134658
SLC35G1	hsa-miR-6838-5p	81.4129	NM_001134658
SLC35G1	hsa-miR-497-5p	81.4129	NM_001134658
SLC35G1	hsa-miR-3529-3p	81.1893	NM_153226

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Motifs and transcription factors (TFs) regulating SLC35G1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
SLC35G1	hdpi__MYEF2	MYEF2 (directAnnotation).
SLC35G1	transfac_pro__M04950	EGR1 (directAnnotation).
SLC35G1	metacluster_55.5	ZNF541 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."