Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: SLC25A23

Summary for SLC25A23

Gene information	Gene symbol	SLC25A23
	Ensembl ID	ENSG00000125648
	Entrez ID	79085
	Gene name	solute carrier family 25 member 23
	Synonyms	APC2\|FLJ30339\|MGC2615
	Gene type	protein_coding
	UniProtAcc	NA

Top

Dataset with differentially expressed gene: SLC25A23

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	1.07833	3.46e-10

Top

Expression of SLC25A23 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to SLC25A23

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating SLC25A23

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
SLC25A23	hsa-miR-4713-3p	99.9965	NM_024103
SLC25A23	hsa-miR-1825	99.7169	NM_024103
SLC25A23	hsa-miR-199b-5p	99.4505	NM_024103
SLC25A23	hsa-miR-199a-5p	99.4505	NM_024103
SLC25A23	hsa-miR-4260	98.5642	NM_024103
SLC25A23	hsa-miR-4661-3p	96.8071	NM_024103
SLC25A23	hsa-miR-6857-5p	95.7844	NM_024103
SLC25A23	hsa-miR-4450	93.9918	NM_024103
SLC25A23	hsa-miR-450a-2-3p	92.5465	NM_024103
SLC25A23	hsa-miR-7113-5p	91.9584	NM_024103
SLC25A23	hsa-miR-4650-3p	91.2647	NM_024103
SLC25A23	hsa-miR-6747-5p	89.9864	NM_024103
SLC25A23	hsa-miR-1227-5p	89.4539	NM_024103
SLC25A23	hsa-miR-4710	89.3879	NM_024103
SLC25A23	hsa-miR-6506-5p	89.058	NM_024103
SLC25A23	hsa-miR-619-5p	88.931	NM_024103
SLC25A23	hsa-miR-4774-5p	88.9132	NM_024103
SLC25A23	hsa-miR-4490	88.9132	NM_024103
SLC25A23	hsa-miR-6824-3p	88.7831	NM_024103
SLC25A23	hsa-miR-6764-3p	88.7831	NM_024103
SLC25A23	hsa-miR-5572	88.3807	NM_024103
SLC25A23	hsa-miR-450b-3p	88.0022	NM_024103
SLC25A23	hsa-miR-573	87.9061	NM_024103
SLC25A23	hsa-miR-769-3p	87.6253	NM_024103
SLC25A23	hsa-miR-6785-5p	87.1313	NM_024103
SLC25A23	hsa-miR-4728-5p	87.1313	NM_024103
SLC25A23	hsa-miR-4654	86.4859	NM_024103
SLC25A23	hsa-miR-6737-5p	85.8803	NM_024103
SLC25A23	hsa-miR-6819-5p	85.8803	NM_024103
SLC25A23	hsa-miR-6812-5p	85.5188	NM_024103
SLC25A23	hsa-miR-1204	85.2542	NM_024103
SLC25A23	hsa-miR-92a-1-5p	84.7628	NM_024103
SLC25A23	hsa-miR-3616-5p	84.173	NM_024103
SLC25A23	hsa-miR-4731-5p	84.0811	NM_024103
SLC25A23	hsa-miR-10401-5p	83.6447	NM_024103
SLC25A23	hsa-miR-149-3p	81.8126	NM_024103
SLC25A23	hsa-miR-6883-5p	81.8126	NM_024103
SLC25A23	hsa-miR-4769-5p	81.7195	NM_024103
SLC25A23	hsa-miR-584-5p	81.0699	NM_024103
SLC25A23	hsa-miR-1207-5p	80.6307	NM_024103
SLC25A23	hsa-miR-4763-3p	80.6307	NM_024103

Page: 1

Top

Motifs and transcription factors (TFs) regulating SLC25A23

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."