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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: RPS3A

Summary for RPS3A

Gene informationGene symbol

RPS3A

Ensembl ID

ENSG00000145425

Entrez ID

6189

Gene nameribosomal protein S3A
SynonymsMFTL|S3A
Gene typeprotein_coding
UniProtAcc

P61247


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Dataset with differentially expressed gene: RPS3A

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE186960

Panc1 cell lineCell linePancreatic cancerPancreatic ductal adenocarcinoma (PDAC)ChemotherapygemcitabineNAMalignant cells1.900260.00e+00

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostPlasma cells0.2964527.03e-03

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostNK cells0.4702430.00e+00

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostcDCs0.4214245.44e-18

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostCD8+ T cells0.5283850.00e+00

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostCD4+ T cells0.4426290.00e+00

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostB cells0.3007260.00e+00

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpreCD4+ T cells-0.379080.00e+00

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpreMono/Macro0.2979550.00e+00

GSE169246_PacBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpreB cells-0.2514740.00e+00

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostB cells0.587310.00e+00

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostCD4+ T cells0.5680790.00e+00

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostcDCs0.4106861.67e-13

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostNK cells0.6288560.00e+00

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostCD8+ T cells0.4971670.00e+00

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpostMono/Macro0.4982470.00e+00

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpreMono/Macro0.5327471.95e-43

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelprePlasma cells1.067050.00e+00

GSE169246_PacTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)ChemotherapypaclitaxelpreCD4+ T cells-0.3573150.00e+00

GSE169246_PacAteBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostMono/Macro-0.3238990.00e+00

GSE169246_PacAteBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostCD8+ T cells0.2506080.00e+00

GSE169246_PacAteBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostB cells0.2981150.00e+00

GSE169246_PacAteBlood

patientsPeripheral blood mononuclear cellsBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpreMono/Macro-0.2885550.00e+00

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostB cells-0.3673337.45e-14

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostCD8+ T cells-0.3005640.00e+00

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostCD4+ T cells-0.8100810.00e+00

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostMono/Macro-1.082661.77e-26

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpostNK cells-0.3797531.15e-05

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpreCD4+ T cells-0.9683830.00e+00

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelprePlasma cells-0.5209157.89e-19

GSE169246_PacAteTissue

patientsTumor tissueBreast cancerAdvanced triple-negative breast cancer (TNBC)Immunotherapyatezolizumab + paclitaxelpreNK cells-0.4593060.00e+00

GSE197268_Axi-cel

patientsPeripheral blood mononuclear cellsAcute lymphoblastic leukemiaLarge B-cell acute lymphoblastic leukemia (B-ALL)Immunotherapyaxi-cel (CAR-T)postcDCs0.3128662.63e-06

GSE197268_Axi-cel

patientsPeripheral blood mononuclear cellsAcute lymphoblastic leukemiaLarge B-cell acute lymphoblastic leukemia (B-ALL)Immunotherapyaxi-cel (CAR-T)postCD8+ T cells-0.4483990.00e+00

GSE197268_Axi-cel

patientsPeripheral blood mononuclear cellsAcute lymphoblastic leukemiaLarge B-cell acute lymphoblastic leukemia (B-ALL)Immunotherapyaxi-cel (CAR-T)postCD4+ T cells-0.3711070.00e+00

GSE164551

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)ImmunotherapyCAR-TNACD8+ T cells0.5200851.72e-13

GSE164551

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)ImmunotherapyCAR-TNANK cells0.5402951.37e-02

GSE164551

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)ImmunotherapyCAR-TNAErythrocytes-1.184561.05e-30

PMID34715028

patientsTumor tissueKidney cancerClear cell renal cell carcinoma (ccRCC)ImmunotherapynivolumabpostCD4+ T cells0.2858275.74e-06

GSE207422_Sin

patientsTumor tissueLung cancerEGFR/ALK mutation negative non-small cell lung cancer (NSCLC)Immunotherapysintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)postCD8+ T cells-0.2851131.32e-07

GSE207422_Sin

patientsTumor tissueLung cancerEGFR/ALK mutation negative non-small cell lung cancer (NSCLC)Immunotherapysintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)postMono/Macro-0.3114561.35e-03

GSE197268_Tisa-cel

patientsPeripheral blood mononuclear cellsAcute lymphoblastic leukemiaLarge B-cell acute lymphoblastic leukemia (B-ALL)Immunotherapytisa-cel (CAR-T)postCD4+ T cells-0.2711160.00e+00

GSE207422_Tor

patientsTumor tissueLung cancerEGFR/ALK mutation negative non-small cell lung cancer (NSCLC)Immunotherapytoripalimab + carboplatin + (docetaxel or pemetrexed or emcitabine)postpDCs-0.7934875.79e-03

GSE207422_Tor

patientsTumor tissueLung cancerEGFR/ALK mutation negative non-small cell lung cancer (NSCLC)Immunotherapytoripalimab + carboplatin + (docetaxel or pemetrexed or emcitabine)postMalignant cells-1.28180.00e+00

GSE207422_Tor

patientsTumor tissueLung cancerEGFR/ALK mutation negative non-small cell lung cancer (NSCLC)Immunotherapytoripalimab + carboplatin + (docetaxel or pemetrexed or emcitabine)postMono/Macro-0.296324.83e-04

GSE189460

patientsBone marrow aspirateMultiple myelomaMultiple myeloma (MM)Targeted therapybortezomib + melphalan + prednisolonepreErythrocytes-0.5394845.45e-27

GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasonepostMono/Macro-0.5281950.00e+00

GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasonepostcDCs-0.6595223.54e-09

GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasonepostB cells-0.4616752.41e-02

GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasonepostNK cells-0.4462151.93e-37

GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasonepostMalignant cells0.2880999.94e-04

GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasonepostCD8+ T cells-0.2777380.00e+00

GSE161801_PI

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapycarfilzomib + dexamethasonepreNK cells-0.5497695.02e-25

GSE139386

H3122 cell lineCell lineLung cancerEML4-ALK fusion-positive non-small cell lung cancer (NSCLC)Targeted therapyceritinibNAMalignant cells0.5231190.00e+00

GSE168668

LNCaP cell lineCell lineProstate cancerProstate cancerTargeted therapyenzalutamideNAMalignant cells-0.3933670.00e+00

GSE149214

PC9 cell lineCell lineLung cancerEGFR-mutated non-small cell lung cancer (NSCLC)Targeted therapyerlotinibNAMalignant cells0.7601370.00e+00

GSE162117

patientsPeripheral blood mononuclear cellsAcute myeloid leukemiaTefractory acute myeloid leukemia (AML)Targeted therapyficlatuzumabpostCD4+ T cells-0.2906722.85e-35

GSE162117

patientsPeripheral blood mononuclear cellsAcute myeloid leukemiaTefractory acute myeloid leukemia (AML)Targeted therapyficlatuzumabpostcDCs-0.310188.78e-33

GSE162117

patientsPeripheral blood mononuclear cellsAcute myeloid leukemiaTefractory acute myeloid leukemia (AML)Targeted therapyficlatuzumabpreMalignant cells0.4200680.00e+00

GSE199333

patientsBone marrow aspirateAcute myeloid leukemiaPrimary FLT3-ITD-mutated acute myeloid leukemia (AML)Targeted therapygilteritinibpostCD8+ T cells0.3899260.00e+00

GSE199333

patientsBone marrow aspirateAcute myeloid leukemiaPrimary FLT3-ITD-mutated acute myeloid leukemia (AML)Targeted therapygilteritinibpostMalignant cells0.4926140.00e+00

GSE199333

patientsBone marrow aspirateAcute myeloid leukemiaPrimary FLT3-ITD-mutated acute myeloid leukemia (AML)Targeted therapygilteritinibpreMalignant cells0.5018920.00e+00

GSE199333

patientsBone marrow aspirateAcute myeloid leukemiaPrimary FLT3-ITD-mutated acute myeloid leukemia (AML)Targeted therapygilteritinibpreCD4+ T cells0.4353311.19e-37

GSE199333

patientsBone marrow aspirateAcute myeloid leukemiaPrimary FLT3-ITD-mutated acute myeloid leukemia (AML)Targeted therapygilteritinibpreCD8+ T cells0.4550771.16e-36

GSE199333

patientsBone marrow aspirateAcute myeloid leukemiaPrimary FLT3-ITD-mutated acute myeloid leukemia (AML)Targeted therapygilteritinibpreB cells-1.822849.03e-09

GSE104987

MCF7 cell lineCell lineBreast cancerER+ breast cancerTargeted therapyKDM5-C70NAMalignant cells0.4184441.07e-37

GSE108397

451Lu cell lineCell lineMelanomaMelanomaTargeted therapyPLX-4720NAMalignant cells0.8064820.00e+00

GSE161801_IMiD

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapypomalidomide + dexamethasone OR lenalidomide + dexamethasonepostCD4+ T cells0.5614811.66e-20

GSE161801_IMiD

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapypomalidomide + dexamethasone OR lenalidomide + dexamethasonepostB cells0.4007971.09e-14

GSE161801_IMiD

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapypomalidomide + dexamethasone OR lenalidomide + dexamethasonepostMalignant cells0.3019710.00e+00

GSE161801_IMiD

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapypomalidomide + dexamethasone OR lenalidomide + dexamethasonepostMono/Macro0.3495080.00e+00

GSE161801_IMiD

patientsBone marrow aspirateMultiple myelomaRefractory multiple myeloma (MM)Targeted therapypomalidomide + dexamethasone OR lenalidomide + dexamethasonepreMalignant cells-0.4100440.00e+00

GSE175716

PDXTumor tissueLiver cancerAdvanced hepatocellular carcinomaTargeted therapysorafenibNAMalignant cells1.439770.00e+00

GSE164897_VemCob

A375 cell lineCell lineMelanomaBRAFV600E-mutant melanomaTargeted therapyvemurafenib + combimetinibNAMalignant cells-0.7939410.00e+00

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Expression of RPS3A in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to RPS3A

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating RPS3A

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
RPS3Ahsa-miR-660-3p93.4358NM_001267699
RPS3Ahsa-miR-5011-5p93.0313NM_001267699
RPS3Ahsa-miR-466392.1435NM_001267699
RPS3Ahsa-miR-3664-3p91.1994NM_001267699
RPS3Ahsa-miR-433089.4604NM_001267699
RPS3Ahsa-miR-345-5p84.3373NM_001267699
RPS3Ahsa-miR-190a-3p83.0733NM_001267699
RPS3Ahsa-miR-6730-5p82.7452NM_001267699
RPS3Ahsa-miR-6867-5p80.4545NM_001267699
RPS3Ahsa-miR-447180.1569NM_001267699
RPS3Ahsa-miR-1292-5p80.1569NM_001267699
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Motifs and transcription factors (TFs) regulating RPS3A

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmotifTF_highConf
RPS3Ametacluster_122.17IRF6 (directAnnotation).
RPS3Ataipale_tf_pairs__ELK1_TEF_NSCGGAWNTTACGTAAN_CAPELK1; TEF (directAnnotation).
RPS3Ataipale_tf_pairs__ETV5_CEBPD_NSCGGANNTTRCGYAAN_CAPCEBPD; ETV5 (directAnnotation).
RPS3Ametacluster_191.2ELK4; NR2C2; NR2C2; NR2C2; NR2C2 (directAnnotation). GABPA (inferredBy_Orthology).
RPS3Ataipale_tf_pairs__ETS2_RCCGGAAGTG_HTETS2 (directAnnotation).
RPS3Ametacluster_166.4BCLAF1; EHF; ELF1; ELF1; ELF1; ELF1; ELF1; ELF1; ELF2; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK3; ELK3; ELK3; ELK3; ELK4; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS1; ETS1; ETS1; ETV1; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV4; ETV4; ETV4; ETV4; ETV5; ETV7; FEV; FEV; FLI1; FLI1; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; GABPB1; GATAD1; PHF20; ZBTB25; ZBTB40 (directAnnotation). EHF; ELF1; ELF1; ELF3; ELF5; ELK3; ELK4; ERG; ETS1; ETV1; ETV2; ETV4; FLI1; GABPA; GABPA (inferredBy_Orthology).
RPS3Ataipale_tf_pairs__MEIS1_ELF1_NTGCCGGAAGTN_CAP_reprELF1; MEIS1 (directAnnotation).
RPS3Ametacluster_191.3EHF; ELF1; ELF1; ELF1; ELF4; ELK1; ELK3; ELK3; ELK4; ELK4; ERF; ETS1; ETS2; ETV3; ETV4; ETV5; FEV; FEV; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; SPDEF; ZNF200 (directAnnotation). ELK1; ELK1; ELK3; ELK3; ELK4; ELK4; ETV1; ETV1; ETV4; ETV4; ETV4; ETV5; GABPA; GABPA (inferredBy_Orthology).
RPS3Ataipale_tf_pairs__ETV5_HOXA2_RSCGGWAATKR_CAPETV5; HOXA2 (directAnnotation).
RPS3Ahdpi__ETV4ETV4 (directAnnotation).
RPS3Ataipale_tf_pairs__ETV5_FOXI1_RSCGGATGTTGN_CAPETV5; FOXI1 (directAnnotation).
RPS3Ataipale_tf_pairs__FOXO1_ELK3_RCCGGAWGTKKW_CAPELK3; FOXO1 (directAnnotation).
RPS3Adbtfbs__GMEB1_K562_ENCSR928KOR_merged_N1GMEB1 (directAnnotation).
RPS3Ataipale_tf_pairs__HOXB2_ETV4_ACCGGAAATGAN_CAPETV4; HOXB2 (directAnnotation).
RPS3Ataipale_tf_pairs__ELF2_NATGCGGAAGTR_HTELF2 (directAnnotation).
RPS3Ahdpi__TP73TP73 (directAnnotation).
RPS3Ataipale_tf_pairs__ERF_HES7_NCCGGAANNNNNNCACGYGNN_CAP_reprERF; HES7 (directAnnotation).
RPS3Ametacluster_19.7GMEB1; GMEB2 (inferredBy_Orthology).
RPS3Ametacluster_138.2ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
RPS3Ametacluster_111.5E4F1; E4F1 (directAnnotation).
RPS3Atransfac_pro__M01861ATF1 (directAnnotation).
RPS3Ataipale_tf_pairs__GCM1_ELK1_RTGCGGGCGGAAGTN_CAP_2ELK1; GCM1 (directAnnotation).
RPS3Ajaspar__MA1509.1IRF6 (directAnnotation).
RPS3Ataipale_tf_pairs__CUX1_SOX15_ATCRATNNNNNNNNSYATTGTT_CAP_reprCUX1; SOX15 (directAnnotation).
RPS3Akznf__ZSCAN16_Schmitges2016_ChIP-seqZSCAN16 (directAnnotation).
RPS3Acisbp__M01802XBP1 (inferredBy_Orthology).
RPS3Atransfac_pro__M05304ZBTB5 (directAnnotation).
RPS3Ataipale_tf_pairs__ETV2_DRGX_RSCGGAWRYATTA_CAP_reprDRGX; ETV2 (directAnnotation).
RPS3Ataipale_tf_pairs__MEIS1_SOX2_TGACAKNNNAACAATGN_CAP_reprMEIS1; SOX2 (directAnnotation).
RPS3Acisbp__M01720ARNT2 (inferredBy_Orthology).
RPS3Aswissregulon__hs__EPAS1EPAS1 (directAnnotation).
RPS3Ahomer__ATTGCGCAAC_CEBPCEBPB (inferredBy_Orthology).
RPS3Atransfac_pro__M07484DNTTIP1 (directAnnotation).
RPS3Atransfac_pro__M05887ZNF837 (directAnnotation).
RPS3Atransfac_pro__M06733RBAK (directAnnotation).
RPS3Ahocomoco__IRX2_HUMAN.H11MO.0.DIRX2 (directAnnotation).
RPS3Atransfac_pro__M02869HOXA3 (inferredBy_Orthology).
RPS3Aswissregulon__hs__CEBPBCEBPB (directAnnotation).
RPS3Ataipale_tf_pairs__ETV7_TBX21_NSCGGAARNNNNNNTCACACNN_CAP_reprETV7; TBX21 (directAnnotation).
RPS3Ataipale_tf_pairs__FOXO1_HOXB13_GWMAACAYMRTAAA_CAPFOXO1; HOXB13 (directAnnotation).
RPS3Atransfac_pro__M06557ZNF418 (directAnnotation).
RPS3Ataipale_cyt_meth__ZNF385D_NCGTCGCGACGN_eDBD_reprZNF385D (directAnnotation).
RPS3Atransfac_pro__M06401ZNF551 (directAnnotation).
RPS3Atransfac_pro__M06129GLI4 (directAnnotation).
RPS3Ataipale_tf_pairs__ELK1_FOXI1_RSCGGAANRWMAACAN_CAP_reprELK1; FOXI1 (directAnnotation).
RPS3Atfdimers__MD00090FOS; FOXG1; FOXO1 (directAnnotation).
RPS3Ataipale_tf_pairs__ETV5_FOXI1_TGTTGNCGGAWRN_CAPETV5; FOXI1 (directAnnotation).
RPS3Ametacluster_71.2EPAS1 (directAnnotation).
RPS3Ataipale_tf_pairs__TEAD4_FOXI1_RCATWCCNNNNNNNNNNNNNRTMAACA_CAP_reprFOXI1; TEAD4 (directAnnotation).
RPS3Atransfac_pro__M05939ZNF471 (directAnnotation).
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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."