Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: RNF41

Summary for RNF41

Gene information	Gene symbol	RNF41
	Ensembl ID	ENSG00000181852
	Entrez ID	10193
	Gene name	ring finger protein 41
	Synonyms	NRDP1\|SBBI03
	Gene type	protein_coding
	UniProtAcc	Q9H4P4

Top

Dataset with differentially expressed gene: RNF41

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE168668	LNCaP cell line	Cell line	Prostate cancer	Prostate cancer	Targeted therapy	enzalutamide	NA	Malignant cells	-0.696043	0.00e+00

Top

Expression of RNF41 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to RNF41

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating RNF41

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
RNF41	hsa-miR-651-3p	98.09	NM_001242826
RNF41	hsa-miR-3182	97.459	NM_001242826
RNF41	hsa-miR-218-5p	96.7119	NM_001242826
RNF41	hsa-miR-16-1-3p	96.0171	NM_001242826
RNF41	hsa-miR-1224-3p	95.0058	NM_001242826
RNF41	hsa-miR-486-3p	92.5233	NM_001242826
RNF41	hsa-miR-3135b	91.4399	NM_001242826
RNF41	hsa-miR-627-3p	91.4141	NM_001242826
RNF41	hsa-miR-5189-3p	90.4078	NM_001242826
RNF41	hsa-miR-6824-5p	89.4811	NM_001242826
RNF41	hsa-miR-3692-5p	88.0908	NM_001242826
RNF41	hsa-miR-4474-3p	87.9311	NM_001242826
RNF41	hsa-miR-548n	87.1466	NM_001242826
RNF41	hsa-miR-8065	86.622	NM_001242826
RNF41	hsa-miR-4284	86.4638	NM_001242826
RNF41	hsa-miR-6783-5p	86.3251	NM_001242826
RNF41	hsa-miR-548p	84.5222	NM_001242826
RNF41	hsa-miR-764	83.7478	NM_001242826
RNF41	hsa-miR-503-5p	83.2834	NM_001242826
RNF41	hsa-miR-644a	82.7032	NM_001242826
RNF41	hsa-miR-6794-3p	82.502	NM_001242826
RNF41	hsa-miR-5692a	82.2113	NM_001242826
RNF41	hsa-miR-3168	82.0574	NM_001242826
RNF41	hsa-miR-514b-5p	80.6219	NM_001242826

Page: 1

Top

Motifs and transcription factors (TFs) regulating RNF41

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."