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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: RBM24

Summary for RBM24

Gene informationGene symbol

RBM24

Ensembl ID

ENSG00000112183

Entrez ID

221662

Gene nameRNA binding motif protein 24
SynonymsdJ259A10.1|FLJ30829|RNPC6
Gene typeprotein_coding
UniProtAcc

Q9BX46


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Dataset with differentially expressed gene: RBM24

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE175716

PDXTumor tissueLiver cancerAdvanced hepatocellular carcinomaTargeted therapysorafenibNAMalignant cells0.5113161.09e-24

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Expression of RBM24 in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to RBM24

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating RBM24

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
RBM24hsa-miR-3121-3p99.759NM_001143941
RBM24hsa-miR-548c-3p99.7567NM_001143941
RBM24hsa-miR-103a-3p97.1722NM_001143941
RBM24hsa-miR-10797.1722NM_001143941
RBM24hsa-miR-548x-3p95.2951NM_153020
RBM24hsa-miR-548aj-3p95.2951NM_153020
RBM24hsa-miR-655-3p95.2085NM_153020
RBM24hsa-miR-374c-5p95.2085NM_153020
RBM24hsa-miR-670-5p95.0035NM_001143941
RBM24hsa-miR-548ah-3p94.8608NM_153020
RBM24hsa-miR-548am-3p94.8608NM_153020
RBM24hsa-miR-548aq-3p94.8608NM_153020
RBM24hsa-miR-548j-3p94.8608NM_153020
RBM24hsa-miR-548ae-3p94.8608NM_153020
RBM24hsa-miR-506-3p94.2907NM_001143941
RBM24hsa-miR-124-3p94.2907NM_001143941
RBM24hsa-miR-6780b-3p93.8456NM_001143941
RBM24hsa-miR-129793.8438NM_001143941
RBM24hsa-miR-5692a93.1626NM_001143941
RBM24hsa-miR-26a-5p92.5743NM_001143941
RBM24hsa-miR-26b-5p92.5743NM_001143941
RBM24hsa-miR-152-3p92.1957NM_001143941
RBM24hsa-miR-148a-3p92.1957NM_001143941
RBM24hsa-miR-148b-3p92.1957NM_001143941
RBM24hsa-miR-323b-3p92.0717NM_153020
RBM24hsa-miR-143-3p91.8303NM_153020
RBM24hsa-miR-477091.8303NM_153020
RBM24hsa-miR-5582-3p91.3561NM_153020
RBM24hsa-miR-446590.8703NM_001143941
RBM24hsa-miR-6760-3p90.4988NM_001143941
RBM24hsa-miR-442990.0661NM_153020
RBM24hsa-miR-320d90.0661NM_153020
RBM24hsa-miR-320a-3p90.0661NM_153020
RBM24hsa-miR-320c90.0661NM_153020
RBM24hsa-miR-320b90.0661NM_153020
RBM24hsa-miR-62389.9665NM_001143941
RBM24hsa-miR-608889.8794NM_153020
RBM24hsa-miR-3944-5p89.0701NM_153020
RBM24hsa-miR-127688.7803NM_153020
RBM24hsa-miR-4445-5p88.6952NM_001143941
RBM24hsa-miR-340-5p88.5202NM_001143941
RBM24hsa-miR-6785-5p88.1006NM_153020
RBM24hsa-miR-4728-5p88.1006NM_153020
RBM24hsa-miR-4687-3p87.7255NM_153020
RBM24hsa-miR-5585-3p87.1232NM_153020
RBM24hsa-miR-3180-5p86.667NM_001143941
RBM24hsa-miR-6883-5p86.406NM_153020
RBM24hsa-miR-149-3p86.406NM_153020
RBM24hsa-miR-6507-5p86.4039NM_153020
RBM24hsa-miR-141-3p86.1437NM_001143941
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Motifs and transcription factors (TFs) regulating RBM24

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmotifTF_highConf
RBM24dbtfbs__GMEB1_K562_ENCSR928KOR_merged_N1GMEB1 (directAnnotation).
RBM24transfac_pro__M04918EGR1 (directAnnotation).
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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."