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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: RAD54B

Summary for RAD54B

Gene information	Gene symbol	RAD54B
	Ensembl ID	ENSG00000197275
	Entrez ID	25788
	Gene name	RAD54 homolog B
	Synonyms	RDH54
	Gene type	protein_coding
	UniProtAcc	Q9Y620

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Dataset with differentially expressed gene: RAD54B

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-1.57042	2.14e-06

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Expression of RAD54B in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to RAD54B

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating RAD54B

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
RAD54B	hsa-miR-587	98.9094	NM_001205262
RAD54B	hsa-miR-3163	98.6716	NM_001205262
RAD54B	hsa-miR-139-5p	94.9987	NM_001205262
RAD54B	hsa-miR-1305	94.73	NM_012415
RAD54B	hsa-miR-548e-5p	93.479	NM_001205262
RAD54B	hsa-miR-506-5p	92.9937	NM_001205262
RAD54B	hsa-miR-3658	92.5845	NM_001205262
RAD54B	hsa-miR-4262	92.0957	NM_001205262
RAD54B	hsa-miR-4775	92.0417	NM_012415
RAD54B	hsa-miR-144-3p	91.6467	NM_001205262
RAD54B	hsa-miR-942-5p	91.2696	NM_001205262
RAD54B	hsa-miR-10226	90.5546	NM_001205262
RAD54B	hsa-miR-383-5p	90.223	NM_001205262
RAD54B	hsa-miR-551b-5p	89.9024	NM_001205262
RAD54B	hsa-miR-371b-5p	89.585	NM_001205262
RAD54B	hsa-miR-373-5p	89.585	NM_001205262
RAD54B	hsa-miR-616-5p	89.585	NM_001205262
RAD54B	hsa-miR-5584-5p	89.4084	NM_001205262
RAD54B	hsa-miR-335-3p	89.3191	NM_012415
RAD54B	hsa-miR-122b-3p	88.8462	NM_001205262
RAD54B	hsa-miR-21-3p	88.8462	NM_001205262
RAD54B	hsa-miR-643	88.4256	NM_001205262
RAD54B	hsa-miR-548aj-3p	88.2984	NM_001205262
RAD54B	hsa-miR-548x-3p	88.2984	NM_001205262
RAD54B	hsa-miR-6847-5p	88.1027	NM_001205262
RAD54B	hsa-miR-181a-5p	87.9858	NM_001205262
RAD54B	hsa-miR-181c-5p	87.9858	NM_001205262
RAD54B	hsa-miR-181d-5p	87.9858	NM_001205262
RAD54B	hsa-miR-181b-5p	87.9858	NM_001205262
RAD54B	hsa-miR-223-5p	87.346	NM_001205262
RAD54B	hsa-miR-513c-3p	87.3272	NM_001205262
RAD54B	hsa-miR-513a-3p	87.3272	NM_001205262
RAD54B	hsa-miR-4668-5p	87.199	NM_001205262
RAD54B	hsa-miR-3148	86.9814	NM_001205262
RAD54B	hsa-miR-765	86.8679	NM_001205262
RAD54B	hsa-miR-3613-3p	86.8398	NM_001205262
RAD54B	hsa-miR-506-3p	86.503	NM_001205262
RAD54B	hsa-miR-124-3p	86.503	NM_001205262
RAD54B	hsa-miR-4495	85.5483	NM_001205262
RAD54B	hsa-miR-548aq-3p	85.5432	NM_001205262
RAD54B	hsa-miR-548ae-3p	85.5432	NM_001205262
RAD54B	hsa-miR-1245a	85.4155	NM_001205262
RAD54B	hsa-miR-8079	85.4155	NM_001205262
RAD54B	hsa-miR-3133	84.3426	NM_001205262
RAD54B	hsa-miR-548j-3p	84.2768	NM_001205262
RAD54B	hsa-miR-548ah-3p	84.2768	NM_001205262
RAD54B	hsa-miR-548am-3p	84.2768	NM_001205262
RAD54B	hsa-miR-3606-3p	83.5931	NM_001205262
RAD54B	hsa-miR-11181-3p	83.2747	NM_001205262
RAD54B	hsa-miR-1-3p	83.2165	NM_012415

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Motifs and transcription factors (TFs) regulating RAD54B

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."