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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: RAB3C

Summary for RAB3C

Gene information	Gene symbol	RAB3C
	Ensembl ID	ENSG00000152932
	Entrez ID	115827
	Gene name	RAB3C, member RAS oncogene family
	Synonyms	NA
	Gene type	protein_coding
	UniProtAcc	Q96E17

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Dataset with differentially expressed gene: RAB3C

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	-0.306924	0.00e+00

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Expression of RAB3C in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to RAB3C

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating RAB3C

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
RAB3C	hsa-miR-6867-5p	99.9999	NM_001317915
RAB3C	hsa-miR-8485	99.5504	NM_001317915
RAB3C	hsa-miR-1305	98.6156	NM_001317915
RAB3C	hsa-miR-4517	98.4802	NM_001317915
RAB3C	hsa-miR-510-3p	97.4045	NM_001317915
RAB3C	hsa-miR-3138	97.1519	NM_001317915
RAB3C	hsa-miR-2682-5p	96.8654	NM_001317915
RAB3C	hsa-miR-34b-5p	96.8529	NM_001317915
RAB3C	hsa-miR-449c-5p	96.8529	NM_001317915
RAB3C	hsa-miR-1253	96.4478	NM_001317915
RAB3C	hsa-miR-4422	95.9694	NM_001317915
RAB3C	hsa-miR-3163	95.9608	NM_001317915
RAB3C	hsa-miR-4277	95.6207	NM_001317915
RAB3C	hsa-miR-4735-5p	95.5651	NM_001317915
RAB3C	hsa-miR-4282	95.4664	NM_001317915
RAB3C	hsa-miR-659-5p	95.3558	NM_001317915
RAB3C	hsa-miR-3680-3p	95.195	NM_001317915
RAB3C	hsa-miR-96-5p	94.6367	NM_001317915
RAB3C	hsa-miR-6868-3p	94.5426	NM_001317915
RAB3C	hsa-miR-4699-5p	94.3989	NM_001317915
RAB3C	hsa-miR-4776-3p	94.2091	NM_001317915
RAB3C	hsa-miR-3605-5p	94.0006	NM_001317915
RAB3C	hsa-miR-3064-3p	93.7041	NM_001317915
RAB3C	hsa-miR-12133	93.6486	NM_001317915
RAB3C	hsa-miR-1271-5p	93.6486	NM_001317915
RAB3C	hsa-miR-3658	93.5364	NM_001317915
RAB3C	hsa-miR-4423-3p	93.5161	NM_001317915
RAB3C	hsa-miR-6874-5p	92.8776	NM_001317915
RAB3C	hsa-miR-3671	92.648	NM_001317915
RAB3C	hsa-miR-338-5p	92.3479	NM_001317915
RAB3C	hsa-miR-6881-3p	91.9317	NM_001317915
RAB3C	hsa-miR-4717-5p	91.5746	NM_001317915
RAB3C	hsa-miR-6502-3p	91.0754	NM_001317915
RAB3C	hsa-miR-6835-3p	90.7974	NM_001317915
RAB3C	hsa-miR-92a-3p	90.7169	NM_001317915
RAB3C	hsa-miR-32-5p	90.7169	NM_001317915
RAB3C	hsa-miR-92b-3p	90.7169	NM_001317915
RAB3C	hsa-miR-6847-5p	90.3582	NM_001317915
RAB3C	hsa-miR-676-5p	90.1083	NM_001317915
RAB3C	hsa-miR-3145-3p	89.7781	NM_001317915
RAB3C	hsa-miR-10527-5p	89.5792	NM_001317915
RAB3C	hsa-miR-4747-5p	89.2207	NM_001317915
RAB3C	hsa-miR-5196-5p	89.2207	NM_001317915
RAB3C	hsa-miR-5000-5p	88.8634	NM_001317915
RAB3C	hsa-miR-3646	88.8146	NM_001317915
RAB3C	hsa-miR-363-3p	88.7934	NM_001317915
RAB3C	hsa-miR-367-3p	88.7934	NM_001317915
RAB3C	hsa-miR-25-3p	88.7934	NM_001317915
RAB3C	hsa-miR-12119	88.7607	NM_001317915
RAB3C	hsa-miR-6511a-5p	88.6731	NM_001317915

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Motifs and transcription factors (TFs) regulating RAB3C

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."