Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: PTPRC

Summary for PTPRC

Gene information	Gene symbol	PTPRC
	Ensembl ID	ENSG00000262418
	Entrez ID	5788
	Gene name	protein tyrosine phosphatase receptor type C
	Synonyms	CD45\|GP180\|LCA\|T200
	Gene type	protein_coding
	UniProtAcc	NA

Top

Dataset with differentially expressed gene: PTPRC

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	post	Plasma cells	-0.39759	1.42e-06
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	NK cells	0.752293	0.00e+00
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	pDCs	0.748262	1.23e-05
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	cDCs	0.574086	1.10e-03
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	Mono/Macro	0.541134	0.00e+00
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	B cells	0.697502	0.00e+00
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	CD4+ T cells	0.78686	0.00e+00
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	CD8+ T cells	0.34016	0.00e+00
GSE169246_PacTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	post	CD8+ T cells	-0.320155	4.74e-27
GSE169246_PacTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	CD8+ T cells	0.667102	0.00e+00
GSE169246_PacTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	CD4+ T cells	0.634952	0.00e+00
GSE169246_PacTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	B cells	0.376672	5.85e-09
GSE169246_PacTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	Plasma cells	0.610374	0.00e+00
GSE169246_PacAteBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	Mono/Macro	-0.426723	0.00e+00
GSE169246_PacAteBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	B cells	-0.257789	4.12e-08
GSE169246_PacAteTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	CD8+ T cells	-0.471554	0.00e+00
GSE169246_PacAteTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	B cells	-0.40125	2.97e-11
GSE169246_PacAteTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	CD4+ T cells	-0.425929	0.00e+00
GSE169246_PacAteTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	NK cells	-0.396767	3.99e-06
GSE169246_PacAteTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	post	Mono/Macro	-0.507883	4.14e-06
GSE169246_PacAteTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Immunotherapy	atezolizumab + paclitaxel	pre	CD4+ T cells	0.296005	0.00e+00
GSE197268_Axi-cel	patients	Peripheral blood mononuclear cells	Acute lymphoblastic leukemia	Large B-cell acute lymphoblastic leukemia (B-ALL)	Immunotherapy	axi-cel (CAR-T)	post	CD8+ T cells	0.262752	0.00e+00
GSE164551	patients	Bone marrow aspirate	Multiple myeloma	Refractory multiple myeloma (MM)	Immunotherapy	CAR-T	NA	Mono/Macro	0.709218	3.88e-39
PMID34715028	patients	Tumor tissue	Kidney cancer	Clear cell renal cell carcinoma (ccRCC)	Immunotherapy	nivolumab	post	CD4+ T cells	-0.295416	2.57e-28
GSE207422_Sin	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	sintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	B cells	-0.503747	4.32e-04
GSE207422_Sin	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	sintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	CD4+ T cells	-0.329736	9.89e-13
GSE207422_Sin	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	sintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	Mono/Macro	-0.438961	4.07e-02
GSE207422_Sin	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	sintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	CD8+ T cells	-0.6333	0.00e+00
GSE197268_Tisa-cel	patients	Peripheral blood mononuclear cells	Acute lymphoblastic leukemia	Large B-cell acute lymphoblastic leukemia (B-ALL)	Immunotherapy	tisa-cel (CAR-T)	post	NK cells	-0.320431	0.00e+00
GSE197268_Tisa-cel	patients	Peripheral blood mononuclear cells	Acute lymphoblastic leukemia	Large B-cell acute lymphoblastic leukemia (B-ALL)	Immunotherapy	tisa-cel (CAR-T)	pre	CD8+ T cells	0.251214	0.00e+00
GSE162117	patients	Peripheral blood mononuclear cells	Acute myeloid leukemia	Tefractory acute myeloid leukemia (AML)	Targeted therapy	ficlatuzumab	post	cDCs	0.298734	1.36e-05
GSE162117	patients	Peripheral blood mononuclear cells	Acute myeloid leukemia	Tefractory acute myeloid leukemia (AML)	Targeted therapy	ficlatuzumab	post	CD4+ T cells	0.320714	1.04e-09
GSE162117	patients	Peripheral blood mononuclear cells	Acute myeloid leukemia	Tefractory acute myeloid leukemia (AML)	Targeted therapy	ficlatuzumab	pre	CD8+ T cells	-0.371103	9.21e-05
GSE162117	patients	Peripheral blood mononuclear cells	Acute myeloid leukemia	Tefractory acute myeloid leukemia (AML)	Targeted therapy	ficlatuzumab	pre	Malignant cells	-0.302491	0.00e+00
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	post	CD4+ T cells	0.765041	0.00e+00
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	post	B cells	1.81682	2.29e-04
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	post	NK cells	0.979755	0.00e+00
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	pre	B cells	-1.73546	7.17e-08
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	pre	Malignant cells	-0.64594	0.00e+00
GSE161801_IMiD	patients	Bone marrow aspirate	Multiple myeloma	Refractory multiple myeloma (MM)	Targeted therapy	pomalidomide + dexamethasone OR lenalidomide + dexamethasone	post	CD8+ T cells	0.328199	0.00e+00

Top

Expression of PTPRC in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to PTPRC

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Gene symbol	Cell type with DEG	Interaction ID	Interacting pair	Gene A	Gene B	Integrin	Interacting cell type1	Interacting cell type2	Dataset	Timepoint	Condition
PTPRC	CD8+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE161801_IMiD	post	resistant
PTPRC	Mono/Macro	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	Mono/Macro	B cells	GSE164551	NA	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteBlood	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacAteBlood	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	Mono/Macro	B cells	GSE169246_PacAteBlood	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacAteBlood	post	resistant
PTPRC	Mono/Macro	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	Mono/Macro	B cells	GSE169246_PacAteBlood	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteBlood	post	sensitive
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacAteBlood	post	sensitive
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	Mono/Macro	B cells	GSE169246_PacAteBlood	post	sensitive
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacAteBlood	post	sensitive
PTPRC	Mono/Macro	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	Mono/Macro	B cells	GSE169246_PacAteBlood	post	sensitive
PTPRC	NK cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacAteTissue	post	resistant
PTPRC	NK cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	Mast cells	GSE169246_PacAteTissue	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	B cells	B cells	GSE169246_PacAteTissue	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteTissue	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacAteTissue	post	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacAteTissue	post	resistant
PTPRC	CD8+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacAteTissue	post	resistant
PTPRC	CD8+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	Mast cells	GSE169246_PacAteTissue	post	resistant
PTPRC	CD4+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteTissue	post	resistant
PTPRC	CD4+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	Mast cells	GSE169246_PacAteTissue	post	resistant
PTPRC	NK cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacAteTissue	post	sensitive
PTPRC	NK cells	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	NK cells	Mono/Macro	GSE169246_PacAteTissue	post	sensitive
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	B cells	B cells	GSE169246_PacAteTissue	post	sensitive
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteTissue	post	sensitive
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacAteTissue	post	sensitive
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacAteTissue	post	sensitive
PTPRC	CD8+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacAteTissue	post	sensitive
PTPRC	CD8+ T cells	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	CD8+ T cells	Mono/Macro	GSE169246_PacAteTissue	post	sensitive
PTPRC	Mono/Macro	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	CD4+ T cells	Mono/Macro	GSE169246_PacAteTissue	post	sensitive
PTPRC	Mono/Macro	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	CD8+ T cells	Mono/Macro	GSE169246_PacAteTissue	post	sensitive
PTPRC	Mono/Macro	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	NK cells	Mono/Macro	GSE169246_PacAteTissue	post	sensitive
PTPRC	CD4+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteTissue	post	sensitive
PTPRC	CD4+ T cells	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	CD4+ T cells	Mono/Macro	GSE169246_PacAteTissue	post	sensitive
PTPRC	CD4+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteTissue	pre	resistant
PTPRC	CD4+ T cells	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	CD4+ T cells	Mono/Macro	GSE169246_PacAteTissue	pre	resistant
PTPRC	CD4+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacAteTissue	pre	sensitive
PTPRC	CD4+ T cells	CPI-SS0822AEF5F	PTPRC_MRC1	PTPRC	MRC1	False	CD4+ T cells	Mono/Macro	GSE169246_PacAteTissue	pre	sensitive
PTPRC	NK cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	CD8+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	CD4+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	B cells	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD4+ T cells	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	Mono/Macro	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	B cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	Mono/Macro	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	Mono/Macro	B cells	GSE169246_PacBlood	pre	resistant
PTPRC	NK cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	NK cells	B cells	GSE169246_PacBlood	pre	sensitive
PTPRC	CD8+ T cells	CPI-SS0CBC7840D	PTPRC_CD22	PTPRC	CD22	False	CD8+ T cells	B cells	GSE169246_PacBlood	pre	sensitive

Page: 1 2 3

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating PTPRC

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
PTPRC	hsa-miR-302a-5p	97.9557	NM_080921
PTPRC	hsa-miR-1283	97.7489	NM_080921
PTPRC	hsa-miR-8076	97.0017	NM_080921
PTPRC	hsa-miR-8485	96.1234	NM_080921
PTPRC	hsa-miR-513c-3p	93.5175	NM_080921
PTPRC	hsa-miR-513a-3p	93.5175	NM_080921
PTPRC	hsa-miR-4531	93.0422	NM_080921
PTPRC	hsa-miR-3606-3p	92.6659	NM_080921
PTPRC	hsa-miR-10523-5p	92.2085	NM_080921
PTPRC	hsa-miR-4662a-3p	91.4364	NM_080921
PTPRC	hsa-miR-6878-5p	91.0175	NM_001267798
PTPRC	hsa-miR-639	88.8703	NM_080921
PTPRC	hsa-miR-586	87.7231	NM_080921
PTPRC	hsa-miR-3692-3p	86.5261	NM_080921
PTPRC	hsa-miR-6755-3p	86.284	NM_080921
PTPRC	hsa-let-7c-3p	85.7374	NM_080921
PTPRC	hsa-miR-3163	85.5808	NM_080921
PTPRC	hsa-miR-5007-3p	85.4357	NM_080921
PTPRC	hsa-miR-590-3p	85.0338	NM_080921
PTPRC	hsa-miR-199a-3p	84.6586	NM_080921
PTPRC	hsa-miR-199b-3p	84.6586	NM_080921
PTPRC	hsa-miR-3129-5p	84.6586	NM_080921
PTPRC	hsa-miR-8069	84.2386	NM_001267798
PTPRC	hsa-miR-6788-5p	83.4524	NM_001267798
PTPRC	hsa-miR-517-5p	81.6652	NM_001267798
PTPRC	hsa-miR-4690-5p	81.3978	NM_001267798
PTPRC	hsa-miR-12123	81.0537	NM_001267798
PTPRC	hsa-miR-664a-3p	80.8033	NM_001267798
PTPRC	hsa-miR-6750-3p	80.6317	NM_001267798
PTPRC	hsa-miR-944	80.2626	NM_001267798

Page: 1

Top

Motifs and transcription factors (TFs) regulating PTPRC

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
PTPRC	taipale_tf_pairs__MEIS1_SOX2_TGACAKNNNAACAATGN_CAP_repr	MEIS1; SOX2 (directAnnotation).
PTPRC	homer__ATTAACACCT_Eomes	EOMES (directAnnotation).
PTPRC	metacluster_90.4	ESR1; ESR1; ESRRA; ESRRA; ESRRA; ESRRA; ESRRA; ESRRA; ESRRA; ESRRA; ESRRB; ESRRB; ESRRB; ESRRB; ESRRG; ESRRG; ESRRG; ESRRG; ESRRG; NR5A1; NR5A1; NR5A1; NR5A2; NR5A2; NR5A2; NR5A2; NR5A2; NR5A2 (directAnnotation). AR; ESR1; ESR2; ESRRA; ESRRA; ESRRA; ESRRB; ESRRB; ESRRB; ESRRB; ESRRG; ESRRG; ESRRG; ESRRG; ESRRG; NR3C1; NR3C2; NR5A1; NR5A2; NR5A2; NR5A2; NR5A2; NR5A2; PGR; RXRG (inferredBy_Orthology).
PTPRC	transfac_pro__M06856	ZNF611 (directAnnotation).
PTPRC	swissregulon__mm__Zbtb4	ZBTB4 (inferredBy_Orthology).
PTPRC	metacluster_144.1	ZNF549 (directAnnotation).
PTPRC	transfac_pro__M05393	ZBTB6 (inferredBy_Orthology).
PTPRC	taipale_tf_pairs__GCM1_ETV7_NTNNNGGCGGAAGNNNTTCCNNN_CAP_repr	ETV7; GCM1 (directAnnotation).
PTPRC	tfdimers__MD00425	ELF5; SMAD4 (directAnnotation).
PTPRC	taipale_tf_pairs__HOXD12_ETV4_RSCGGAAGTAATAAAN_CAP	ETV4; HOXD12 (directAnnotation).
PTPRC	transfac_pro__M05762	ZNF774 (directAnnotation).
PTPRC	transfac_pro__M05479	ZNF580 (directAnnotation).
PTPRC	taipale_tf_pairs__E2F3_TBX21_NGGTGTGNNGGCGCSN_CAP_repr	E2F3; TBX21 (directAnnotation).
PTPRC	taipale_tf_pairs__FOXO1_ELF1_NNGAAAACCGAANM_CAP	ELF1; FOXO1 (directAnnotation).
PTPRC	tfdimers__MD00157	MYB; TLX2 (directAnnotation).
PTPRC	tfdimers__MD00297	POU5F1; ZEB1 (directAnnotation).
PTPRC	metacluster_11.1	ZNF667 (directAnnotation).
PTPRC	tfdimers__MD00127	HOXA13; TFAP2C (directAnnotation).
PTPRC	taipale_tf_pairs__FLI1_DLX2_RSCGGAARYAATTA_CAP	DLX2; FLI1 (directAnnotation).
PTPRC	metacluster_20.5	DLX1; DLX4; DLX4 (directAnnotation).
PTPRC	metacluster_157.2	ATF3; ATF3; ATF3; BACH1; BACH1; BACH1; BACH2; BACH2; BACH2; BACH2; BATF; BATF; BCL11A; FOS; FOS; FOS; FOS; FOS; FOS; FOSB; FOSL1; FOSL1; FOSL1; FOSL1; FOSL1; FOSL1; FOSL2; FOSL2; FOSL2; JDP2; JDP2; JDP2; JDP2; JDP2; JDP2; JDP2; JUN; JUN; JUN; JUN; JUN; JUNB; JUNB; JUNB; JUNB; JUNB; JUNB; JUND; JUND; JUND; JUND; JUND; JUND; JUND; JUND; JUND; MAF; MAFB; MAFF; MAFG; MAFK; NFE2; NFE2; NFE2; NFE2; NFE2; NFE2; NFE2L1; NFE2L1; NFE2L2; NFE2L3; ZNF3; ZSCAN5C (directAnnotation). FOSL1; JUN; JUN; JUN; JUNB; JUNB; JUND (inferredBy_Orthology).
PTPRC	dbtfbs__FEZF1_HEK293_ENCSR827NWO_merged_N1	FEZF1 (directAnnotation).
PTPRC	taipale_tf_pairs__FLI1_FOXI1_GAAAACCGAAAN_CAP_repr	FLI1; FOXI1 (directAnnotation).
PTPRC	tfdimers__MD00147	ELF5; TFAP2C (directAnnotation).
PTPRC	metacluster_0.5	ZNF264 (directAnnotation).
PTPRC	metacluster_183.3	EHF; ELF3; FLI1; SPIB (directAnnotation). EHF; EHF; ELF2; ELF3; ELF4; ELF5; ERG; ERG; ETV3; ETV6; FLI1; SPI1; SPI1 (inferredBy_Orthology).
PTPRC	transfac_pro__M01217	NR4A1 (directAnnotation).
PTPRC	metacluster_9.47	PAX7 (inferredBy_Orthology).
PTPRC	hdpi__FLI1	FLI1 (directAnnotation).
PTPRC	taipale_tf_pairs__HOXB2_ETV4_ACCGGAAATGAN_CAP	ETV4; HOXB2 (directAnnotation).
PTPRC	transfac_pro__M06230	ZSCAN2 (inferredBy_Orthology).
PTPRC	tfdimers__MD00554	CUX1; EP300 (directAnnotation).
PTPRC	taipale_tf_pairs__TEAD4_ELK1_RGAATSCGGAAGYN_CAP	ELK1; TEAD4 (directAnnotation).
PTPRC	taipale_tf_pairs__GCM2_TBX21_AGGTGTNNNGSGGGN_CAP_repr	GCM2; TBX21 (directAnnotation).
PTPRC	hdpi__YEATS4	YEATS4 (directAnnotation).
PTPRC	taipale_tf_pairs__ETV2_FOXO6_RCCGGATGTTKWN_CAP	ETV2; FOXO6 (directAnnotation).
PTPRC	taipale_tf_pairs__FOXO1_ELK1_RSCGGATGTTRTN_CAP	ELK1; FOXO1 (directAnnotation).
PTPRC	taipale_tf_pairs__ELK1_TBX21_TNRCACCGGAAGNN_CAP_repr	ELK1; TBX21 (directAnnotation).
PTPRC	metacluster_31.7	FOXO1; FOXO3; FOXO6 (directAnnotation).
PTPRC	metacluster_84.7	RARA (directAnnotation).
PTPRC	taipale_tf_pairs__HOXB2_TBX21_NAGGTGNTAATKR_CAP	HOXB2; TBX21 (directAnnotation).
PTPRC	transfac_pro__M06188	ZNF135 (directAnnotation).
PTPRC	metacluster_79.1	ZNF713; ZNF713; ZNF713 (directAnnotation).
PTPRC	metacluster_50.1	BATF; BATF; BATF; BATF; BNC2; FOS; FOSB; FOSL1; FOSL1; IRF4; JUN; JUN; JUNB; JUNB; JUNB; JUNB; JUND; JUND; JUND; JUND; JUND; SMAD2; SMAD3 (directAnnotation). BATF; BATF; BATF; FOS; FOSL1; FOSL2; JDP2; JUN; JUN; JUND (inferredBy_Orthology).
PTPRC	kznf__ZNF805_Imbeault2017_RP_RCADE	ZNF805 (directAnnotation).
PTPRC	transfac_pro__M06342	ZNF329 (inferredBy_Orthology).
PTPRC	transfac_pro__M04846	MEF2C (directAnnotation).
PTPRC	transfac_pro__M04862	NRF1 (directAnnotation).
PTPRC	transfac_pro__M06104	ZNF16 (directAnnotation).
PTPRC	transfac_pro__M06062	ZNF623 (directAnnotation).

Page: 1 2 3 4

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."