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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target

Gene: PTPN1

Summary for PTPN1

Gene information	Gene symbol	PTPN1
	Ensembl ID	ENSG00000196396
	Entrez ID	5770
	Gene name	protein tyrosine phosphatase non-receptor type 1
	Synonyms	PTP1B
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: PTPN1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE138267	CDX	Tumor tissue	Lung cancer	Small cell lung cancer (SCLC)	Chemotherapy	NA	NA	Malignant cells	0.266666	0.00e+00
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	B cells	0.303437	0.00e+00
GSE169246_PacTissue	patients	Tumor tissue	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	B cells	0.410444	2.40e-22
GSE207422_Sin	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	sintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	Mono/Macro	0.257092	1.11e-02
GSE207422_Sin	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	sintilimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	B cells	0.501826	3.84e-08
GSE207422_Tor	patients	Tumor tissue	Lung cancer	EGFR/ALK mutation negative non-small cell lung cancer (NSCLC)	Immunotherapy	toripalimab + carboplatin + (docetaxel or pemetrexed or emcitabine)	post	B cells	-0.936694	1.60e-07
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	post	CD4+ T cells	-0.329222	0.00e+00
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	post	Malignant cells	-0.451026	0.00e+00
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	pre	Malignant cells	-0.286989	0.00e+00
GSE131984_JQ1Pal	SUM159 cell line	Cell line	Breast cancer	Triple-negative breast cancer (TNBC)	Targeted therapy	JQ1 + palbociclib	NA	Malignant cells	0.358652	1.05e-18
GSE108397	451Lu cell line	Cell line	Melanoma	Melanoma	Targeted therapy	PLX-4720	NA	Malignant cells	-0.310883	0.00e+00
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	0.358846	0.00e+00

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Expression of PTPN1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to PTPN1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Gene symbol	Mechanism
PTPN1	Unusual Activation of Pro-survival Pathway

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MicroRNAs (miRNA) regulating PTPN1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
PTPN1	hsa-miR-9851-5p	93.8289	NM_001278618
PTPN1	hsa-miR-544b	93.0512	NM_001278618
PTPN1	hsa-miR-3910	92.8547	NM_001278618
PTPN1	hsa-miR-3622a-3p	92.4287	NM_001278618
PTPN1	hsa-miR-3622b-3p	92.4287	NM_001278618
PTPN1	hsa-miR-4700-3p	92.2807	NM_001278618
PTPN1	hsa-miR-2116-5p	92.2302	NM_001278618
PTPN1	hsa-miR-22-5p	92.2302	NM_001278618
PTPN1	hsa-miR-6853-3p	91.8531	NM_001278618
PTPN1	hsa-miR-206	89.1957	NM_001278618
PTPN1	hsa-miR-1-3p	89.1957	NM_001278618
PTPN1	hsa-miR-498-5p	89.0308	NM_001278618
PTPN1	hsa-miR-3663-3p	88.7689	NM_001278618
PTPN1	hsa-miR-6769b-3p	88.4167	NM_001278618
PTPN1	hsa-miR-4723-3p	88.4167	NM_001278618
PTPN1	hsa-miR-613	88.008	NM_001278618
PTPN1	hsa-miR-3183	87.9992	NM_001278618
PTPN1	hsa-miR-4436a	87.2852	NM_001278618
PTPN1	hsa-miR-3613-3p	86.7385	NM_001278618
PTPN1	hsa-miR-2110	85.5236	NM_001278618
PTPN1	hsa-miR-548an	84.8304	NM_001278618
PTPN1	hsa-miR-1301-3p	84.5035	NM_001278618
PTPN1	hsa-miR-5047	84.5035	NM_001278618
PTPN1	hsa-miR-5580-5p	83.7685	NM_001278618
PTPN1	hsa-miR-5000-3p	83.6344	NM_001278618
PTPN1	hsa-miR-1228-3p	83.2684	NM_001278618
PTPN1	hsa-miR-4677-3p	83.0706	NM_001278618
PTPN1	hsa-miR-3913-3p	82.6313	NM_001278618
PTPN1	hsa-miR-6743-5p	82.2124	NM_001278618
PTPN1	hsa-miR-4688	82.2124	NM_001278618
PTPN1	hsa-miR-4677-5p	81.4239	NM_001278618
PTPN1	hsa-miR-5089-3p	80.9054	NM_001278618

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Motifs and transcription factors (TFs) regulating PTPN1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
PTPN1	metacluster_7.13	ZFX (directAnnotation).
PTPN1	metacluster_170.2	KLF1; KLF10; KLF10; KLF11; KLF11; KLF11; KLF12; KLF12; KLF14; KLF15; KLF17; KLF2; KLF5; KLF7; KLF7; KLF8; MAZ; MAZ; PATZ1; SP1; SP1; SP1; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP4; SP4; SP5; SP6; SP7; SP8; SP9; ZNF281 (directAnnotation). E2F1; E2F4; KLF10; KLF13; KLF14; KLF17; KLF2; KLF7; SP1; SP1; SP3; SP4; SP5; SP6; SP7 (inferredBy_Orthology).
PTPN1	jaspar__MA0079.5	SP1 (directAnnotation).
PTPN1	taipale_tf_pairs__E2F1_HES7_RRCRCGYGYNNNNSGCGCSN_CAP_repr	E2F1; HES7 (directAnnotation).
PTPN1	metacluster_195.2	EGR2; KLF10; KLF10; KLF11; KLF11; KLF11; KLF13; KLF13; KLF13; KLF13; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF15; KLF15; KLF16; KLF3; KLF8; KLF9; KLF9; KLF9; SP1; SP1; SP1; SP3; SP3; SP4; SP8; SP8; SP8; SP9; SP9 (directAnnotation). EGR1; KLF1; KLF12; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF14; KLF16; KLF17; KLF17; KLF17; KLF17; KLF18; KLF18; KLF18; KLF18; KLF18; KLF18; KLF2; KLF2; KLF2; KLF3; KLF4; KLF5; KLF5; KLF5; KLF6; KLF7; KLF7; KLF8; KLF9; SP1; SP3; SP4; SP4; SP5; SP5; SP5; SP6; SP7; SP8; SP9 (inferredBy_Orthology).
PTPN1	metacluster_3.14	WT1; WT1 (directAnnotation).
PTPN1	taipale_tf_pairs__GCM1_SPDEF_RTGNKGGCGGAWG_CAP_repr	GCM1; SPDEF (directAnnotation).
PTPN1	transfac_pro__M01219	SP1 (directAnnotation). SP3 (inferredBy_Orthology).
PTPN1	transfac_pro__M07397	ZNF148 (directAnnotation).
PTPN1	metacluster_131.7	EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR1; EGR2; EGR2; EGR2; EGR2; EGR2; EGR2; EGR3; EGR3; EGR3; EGR3; EGR3; EGR3; EGR4; EGR4; WT1 (directAnnotation). EGR1; EGR1; EGR1; EGR1; EGR1; EGR2; EGR2; EGR2; EGR2; EGR2; EGR3; EGR3; WT1; ZBTB43; ZBTB43; ZBTB43; ZBTB43; ZBTB5; ZBTB5; ZBTB5; ZBTB5; ZBTB7A; ZBTB7A; ZBTB7A; ZBTB7A; ZNF367; ZNF367; ZNF367; ZNF367; ZNF740; ZNF740; ZNF740; ZNF740 (inferredBy_Orthology).
PTPN1	homer__GGGGGGGG_Maz	MAZ (directAnnotation).
PTPN1	taipale_cyt_meth__ZNF460_NRMCGCCCCCCGN_eDBD_meth	ZNF460 (directAnnotation).
PTPN1	tfdimers__MD00151	CHURC1 (directAnnotation).
PTPN1	transfac_pro__M01303	SP1 (directAnnotation).
PTPN1	transfac_pro__M01714	KLF15 (directAnnotation).
PTPN1	hocomoco__PROX1_HUMAN.H11MO.0.D	PROX1 (directAnnotation).
PTPN1	metacluster_3.5	KLF14; KLF15; KLF15; KLF16 (directAnnotation).
PTPN1	homer__GGCGGGAARN_E2F6	E2F6 (directAnnotation).
PTPN1	transfac_pro__M07436	WT1 (directAnnotation).
PTPN1	transfac_pro__M02281	SP1 (directAnnotation).
PTPN1	kznf__ZNF730_Imbeault2017_RP_RCADE	ZNF730 (directAnnotation).
PTPN1	transfac_pro__M02898	SMAD3 (directAnnotation).
PTPN1	transfac_public__M00491	PATZ1 (directAnnotation).
PTPN1	transfac_pro__M02913	SP140 (inferredBy_Orthology).
PTPN1	transfac_pro__M01090	SMAD9 (inferredBy_Orthology).
PTPN1	transfac_pro__M02865	GMEB1 (inferredBy_Orthology).
PTPN1	transfac_pro__M08894	OVOL1; OVOL2 (directAnnotation).
PTPN1	hdpi__RARA	RARA (directAnnotation).
PTPN1	jaspar__MA1721.1	ZNF93 (directAnnotation).
PTPN1	metacluster_144.8	ZNF30; ZNF30 (directAnnotation).
PTPN1	metacluster_133.1	ZNF304; ZNF304; ZSCAN22 (directAnnotation).
PTPN1	taipale_tf_pairs__TFAP2C_E2F8_NNTCCCGCNNNCCNNNGGC_CAP_repr	E2F8; TFAP2C (directAnnotation).
PTPN1	kznf__ZNF311_Imbeault2017_OM_MEME	ZNF311 (directAnnotation).
PTPN1	metacluster_23.9	GLIS1; GLIS3; GLIS3; ZNF575 (directAnnotation). GLIS2; GLIS2; GLIS3; ZNF575; ZXDA; ZXDA; ZXDA; ZXDA; ZXDB; ZXDB; ZXDB; ZXDB; ZXDC; ZXDC; ZXDC; ZXDC (inferredBy_Orthology).
PTPN1	metacluster_125.2	TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2D; TFAP2D; TFAP2D; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; ZNF611; ZNF611 (directAnnotation). TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E (inferredBy_Orthology).
PTPN1	transfac_pro__M02786	PLAGL1 (inferredBy_Orthology).
PTPN1	transfac_pro__M01973	PLAG1 (directAnnotation).
PTPN1	metacluster_198.3	ZFP64 (directAnnotation).
PTPN1	transfac_pro__M02861	GATA6 (inferredBy_Orthology).
PTPN1	metacluster_143.13	ZBTB7A (directAnnotation).
PTPN1	transfac_pro__M07387	ZBTB7A (directAnnotation).
PTPN1	kznf__ZNF383_Imbeault2017_RP_RCADE	ZNF383 (directAnnotation).
PTPN1	transfac_public__M00189	TFAP2A; TFAP2B; TFAP2C (directAnnotation).
PTPN1	metacluster_196.3	NR1H4; NR2F6; PRDM14; ZNF264; ZNF264 (directAnnotation). HNF4A; HNF4G; NR1D1; NR1D1; NR1D1; NR1D2; NR1D2; NR1D2; NR1H2; NR1H2; NR1H2; NR1H3; NR1H3; NR1H3; NR1I2; NR1I2; NR1I2; NR2C1; NR2C2; NR2F2; NR2F6; PPARA; PPARA; PPARA; PPARD; PPARD; PPARD; PPARG; PPARG; PPARG; RARA; RARA; RARA; RARB; RARB; RARB; RORA; RORA; RORA; RORB; RORB; RORB; RORC; RORC; RORC; RXRA; RXRB; RXRG; THRA; THRA; THRA; VDR; VDR; VDR (inferredBy_Orthology).
PTPN1	taipale_tf_pairs__TFAP2C_HES7_NNCRCGYGNNNNNNSCCNNNGGS_CAP_repr	HES7; TFAP2C (directAnnotation).
PTPN1	kznf__ZNF213_Schmitges2016_RCADE	ZNF213 (directAnnotation).
PTPN1	taipale_cyt_meth__E2F2_NCGCGCGCGCM_eDBD_meth	E2F2 (directAnnotation).
PTPN1	cisbp__M00249	WT1 (directAnnotation).
PTPN1	transfac_pro__M01122	ZNF219 (directAnnotation).
PTPN1	swissregulon__hs__GLIS2	GLIS2 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

Target name	Drug name	Drug ID	Drug type
PTPN1	"(3R)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER"	DB08549	small molecule
PTPN1	"(4-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-methoxy-3-oxopropyl}phenyl)methaneseleninic acid"	DB08783	small molecule
PTPN1	"(4S)-5-[[(2S)-1-[[(2S)-1-Amino-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[4	DB03483	small molecule
PTPN1	"1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE"	DB08593	small molecule
PTPN1	"1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID"	DB04800	small molecule
PTPN1	"2-(Oxalyl-Amino)-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid"	DB03670	small molecule
PTPN1	"2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid"	DB03102	small molecule
PTPN1	"2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Thiopyran-3-Carboxylic Acid"	DB02072	small molecule
PTPN1	"2-(Oxalyl-Amino)-Benzoic Acid"	DB02622	small molecule
PTPN1	"2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID"	DB07295	small molecule
PTPN1	"2-[{4-[(2S)-2-{[(Allyloxy)carbonyl]amino}-3-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-	DB04088	small molecule
PTPN1	"2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid"	DB01820	small molecule
PTPN1	"3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid (4-Sulfamoyl-Phenyl)-Amide"	DB02259	small molecule
PTPN1	"3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide"	DB04142	small molecule
PTPN1	"3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phe	DB03311	small molecule
PTPN1	"3-(4-{2-[2-(2-bromo-acetylamino)-ethyldisulfanyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-pyrazine-2-c	DB02620	small molecule
PTPN1	"3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID"	DB07298	small molecule
PTPN1	"3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid"	DB01734	small molecule
PTPN1	"4-BROMO-3-(CARBOXYMETHOXY)-5-(4-HYDROXYPHENYL)THIOPHENE-2-CARBOXYLIC ACID"	DB07197	small molecule
PTPN1	"4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID"	DB07130	small molecule
PTPN1	"4-BROMO-3-(CARBOXYMETHOXY)-5-[3-(CYCLOHEXYLAMINO)PHENYL]THIOPHENE-2-CARBOXYLIC ACID"	DB06829	small molecule
PTPN1	"4-Carbamoyl-4-{[6-(Difluoro-Phosphono-Methyl)-Naphthalene-2-Carbonyl]-Amino}-Butyric Acid"	DB03714	small molecule
PTPN1	"4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN"	DB07480	small molecule
PTPN1	"4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid"	DB08147	small molecule
PTPN1	"4-[[(2S)-1-[[6-[(1-Amino-1-oxo-3-sulfanylpropan-2-yl)amino]-6-oxohexyl]amino]-3-[4-[difluoro(phosph	DB03557	small molecule
PTPN1	"5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-ca	DB02014	small molecule
PTPN1	"5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE"	DB07730	small molecule
PTPN1	"5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXY	DB08001	small molecule
PTPN1	"5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE"	DB07134	small molecule
PTPN1	"5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE"	DB08591	small molecule
PTPN1	"5-[3-(BENZYLAMINO)PHENYL]-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID"	DB07289	small molecule
PTPN1	"6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBOXYLIC ACID"	DB08397	small molecule
PTPN1	"6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid"	DB04001	small molecule
PTPN1	"7-(1,1-Dioxo-1h-Benzo[D]Isothiazol-3-Yloxymethyl)-2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyra	DB02827	small molecule
PTPN1	"Compound 19"	DB02615	small molecule
PTPN1	"Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid"	DB03982	small molecule
PTPN1	"Ertiprotafib"	DB06521	small molecule
PTPN1	"ISIS 113715"	DB05506	small molecule
PTPN1	"ISOTHIAZOLIDINONE ANALOG"	DB08003	small molecule
PTPN1	"L-cysteic acid"	DB03661	small molecule
PTPN1	"N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide"	DB04525	small molecule
PTPN1	"N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide"	DB02784	small molecule
PTPN1	"N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE"	DB07651	small molecule
PTPN1	"Novo Nordisk a/S Compound"	DB02662	small molecule
PTPN1	"p-Benzoyl-L-phenylalanine"	DB08371	small molecule
PTPN1	"PNU177836"	DB02977	small molecule
PTPN1	"Trodusquemine"	DB06333	small molecule
PTPN1	"[(3R)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl	DB07719	small molecule
PTPN1	"[(3S)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl	DB06887	small molecule
PTPN1	"[(4-{4-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Butyl}-Phenyl)-Difluoro-Methyl]-Phosphonic Acid"	DB04204	small molecule

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1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."