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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: POMGNT1

Summary for POMGNT1

Gene information	Gene symbol	POMGNT1
	Ensembl ID	ENSG00000085998
	Entrez ID	55624
	Gene name	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
	Synonyms	FLJ20277\|LGMD2O\|MEB\|MGAT1.2
	Gene type	protein_coding
	UniProtAcc	Q8WZA1

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Dataset with differentially expressed gene: POMGNT1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE108397	451Lu cell line	Cell line	Melanoma	Melanoma	Targeted therapy	PLX-4720	NA	Malignant cells	-0.881104	0.00e+00
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.331916	1.71e-34

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Expression of POMGNT1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to POMGNT1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating POMGNT1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
POMGNT1	hsa-miR-3121-3p	98.6965	NM_017739
POMGNT1	hsa-miR-4638-3p	94.8943	NM_017739
POMGNT1	hsa-miR-95-5p	93.9646	NM_017739
POMGNT1	hsa-miR-3184-3p	92.6949	NM_017739
POMGNT1	hsa-miR-3921	89.4676	NM_017739
POMGNT1	hsa-miR-4653-5p	89.4676	NM_017739
POMGNT1	hsa-miR-5586-5p	87.5914	NM_001290129
POMGNT1	hsa-miR-4303	87.3907	NM_017739
POMGNT1	hsa-miR-1283	84.5331	NM_017739
POMGNT1	hsa-miR-1200	84.4936	NM_017739
POMGNT1	hsa-miR-593-3p	83.6403	NM_017739
POMGNT1	hsa-miR-4267	82.2161	NM_017739
POMGNT1	hsa-miR-6748-3p	81.0708	NM_001290129
POMGNT1	hsa-miR-3664-3p	80.8929	NM_017739

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Motifs and transcription factors (TFs) regulating POMGNT1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."