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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: PEX19

Summary for PEX19

Gene information	Gene symbol	PEX19
	Ensembl ID	ENSG00000162735
	Entrez ID	5824
	Gene name	peroxisomal biogenesis factor 19
	Synonyms	D1S2223E\|HK33\|PMP1\|PMPI\|PXF\|PXMP1
	Gene type	protein_coding
	UniProtAcc	P40855

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Dataset with differentially expressed gene: PEX19

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	0.826039	0.00e+00

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Expression of PEX19 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to PEX19

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating PEX19

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
PEX19	hsa-miR-6758-5p	97.7558	NM_002857
PEX19	hsa-miR-6856-5p	97.6067	NM_002857
PEX19	hsa-miR-8063	90.7784	NM_002857
PEX19	hsa-miR-518c-5p	86.9765	NM_002857
PEX19	hsa-miR-3065-3p	86.6152	NM_002857
PEX19	hsa-miR-5699-5p	86.0854	NM_002857
PEX19	hsa-miR-183-5p	86.065	NM_002857
PEX19	hsa-miR-4693-3p	84.5111	NM_002857
PEX19	hsa-miR-211-5p	84.0801	NM_002857
PEX19	hsa-miR-204-5p	84.0801	NM_002857
PEX19	hsa-miR-3143	82.7479	NM_002857
PEX19	hsa-miR-5006-3p	81.8369	NM_002857
PEX19	hsa-miR-4755-5p	81.8369	NM_002857
PEX19	hsa-miR-6728-5p	81.7371	NM_002857
PEX19	hsa-miR-3670	81.5481	NM_002857
PEX19	hsa-miR-4297	81.1945	NM_002857

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Motifs and transcription factors (TFs) regulating PEX19

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."