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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: PABPC4L

Summary for PABPC4L

Gene information	Gene symbol	PABPC4L
	Ensembl ID	ENSG00000254535
	Entrez ID	132430
	Gene name	poly(A) binding protein cytoplasmic 4 like
	Synonyms	NA
	Gene type	protein_coding
	UniProtAcc	P0CB38

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Dataset with differentially expressed gene: PABPC4L

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-1.58623	6.65e-03

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Expression of PABPC4L in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to PABPC4L

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating PABPC4L

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
PABPC4L	hsa-miR-4503	96.7065	NM_001114734
PABPC4L	hsa-miR-3671	96.2243	NM_001114734
PABPC4L	hsa-miR-329-5p	92.9656	NM_001114734
PABPC4L	hsa-miR-4698	91.572	NM_001114734
PABPC4L	hsa-miR-4760-5p	90.2047	NM_001114734
PABPC4L	hsa-miR-4699-3p	90.1233	NM_001114734
PABPC4L	hsa-miR-4490	89.0434	NM_001114734
PABPC4L	hsa-miR-8061	88.9182	NM_001114734
PABPC4L	hsa-miR-4282	88.7312	NM_001114734
PABPC4L	hsa-miR-448	88.3966	NM_001114734
PABPC4L	hsa-miR-548c-3p	87.7584	NM_001114734
PABPC4L	hsa-miR-361-5p	87.5064	NM_001114734
PABPC4L	hsa-miR-4692	86.735	NM_001114734
PABPC4L	hsa-miR-5009-3p	86.5835	NM_001114734
PABPC4L	hsa-miR-4511	85.7471	NM_001114734
PABPC4L	hsa-miR-513c-3p	85.7432	NM_001114734
PABPC4L	hsa-miR-513a-3p	85.7432	NM_001114734
PABPC4L	hsa-miR-3692-3p	83.8885	NM_001114734
PABPC4L	hsa-miR-6818-5p	83.8174	NM_001114734
PABPC4L	hsa-miR-4514	83.5793	NM_001114734
PABPC4L	hsa-miR-1323	83.391	NM_001114734
PABPC4L	hsa-miR-659-3p	83.3833	NM_001114734
PABPC4L	hsa-miR-3606-3p	83.0726	NM_001114734
PABPC4L	hsa-miR-335-3p	82.8809	NM_001114734
PABPC4L	hsa-miR-4762-3p	82.6202	NM_001114734
PABPC4L	hsa-miR-124-3p	81.9132	NM_001114734
PABPC4L	hsa-miR-506-3p	81.9132	NM_001114734
PABPC4L	hsa-miR-548o-3p	81.6184	NM_001114734
PABPC4L	hsa-miR-5011-5p	81.4143	NM_001114734
PABPC4L	hsa-miR-577	81.27	NM_001114734
PABPC4L	hsa-miR-8055	80.843	NM_001114734
PABPC4L	hsa-miR-2115-3p	80.3322	NM_001114734
PABPC4L	hsa-miR-1305	80.1661	NM_001114734

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Motifs and transcription factors (TFs) regulating PABPC4L

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."