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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: NBPF15

Summary for NBPF15

Gene information	Gene symbol	NBPF15
	Ensembl ID	ENSG00000266338
	Entrez ID	284565
	Gene name	NBPF member 15
	Synonyms	MGC8902\|NBPF16
	Gene type	protein_coding
	UniProtAcc	Q8N660

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Dataset with differentially expressed gene: NBPF15

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	CD4+ T cells	0.250299	0.00e+00

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Expression of NBPF15 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to NBPF15

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating NBPF15

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
NBPF15	hsa-miR-4478	91.9997	NM_173638
NBPF15	hsa-miR-6499-3p	91.9082	NM_173638
NBPF15	hsa-miR-3929	91.1298	NM_173638
NBPF15	hsa-miR-141-3p	90.7623	NM_173638
NBPF15	hsa-miR-4520-2-3p	89.6844	NM_173638
NBPF15	hsa-miR-200a-3p	88.234	NM_173638
NBPF15	hsa-miR-3622b-5p	87.9692	NM_173638
NBPF15	hsa-miR-6852-3p	86.2519	NM_173638
NBPF15	hsa-miR-33a-3p	86.0492	NM_173638
NBPF15	hsa-miR-6832-5p	85.4395	NM_173638
NBPF15	hsa-miR-5093	85.1146	NM_173638
NBPF15	hsa-miR-152-5p	84.9793	NM_173638
NBPF15	hsa-miR-6818-3p	84.4381	NM_173638
NBPF15	hsa-miR-6894-3p	84.3475	NM_173638
NBPF15	hsa-miR-580-3p	84.0158	NM_173638
NBPF15	hsa-miR-3529-3p	83.3302	NM_173638
NBPF15	hsa-miR-4692	81.8402	NM_173638
NBPF15	hsa-miR-4443	80.7881	NM_173638
NBPF15	hsa-miR-4514	80.1815	NM_173638

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Motifs and transcription factors (TFs) regulating NBPF15

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
NBPF15	flyfactorsurvey__Mad_FlyReg_FBgn0011648	SMAD9 (inferredBy_Orthology).
NBPF15	hdpi__NRL	NRL (directAnnotation).
NBPF15	transfac_pro__M02933	ZBTB14 (inferredBy_Orthology).
NBPF15	transfac_pro__M02089	E2F3 (directAnnotation).
NBPF15	transfac_pro__M12697	ZNF142 (directAnnotation).
NBPF15	transfac_pro__M00716	ZBTB14 (directAnnotation).
NBPF15	transfac_pro__M01090	SMAD9 (inferredBy_Orthology).
NBPF15	transfac_pro__M00803	E2F1; E2F3; E2F4; TFDP1 (directAnnotation).
NBPF15	transfac_pro__M04916	TAF1 (directAnnotation).
NBPF15	dbtfbs__ZBTB8A_HEK293_ENCSR481FEC_merged_N1	ZBTB8A (directAnnotation).
NBPF15	metacluster_7.13	ZFX (directAnnotation).
NBPF15	transfac_pro__M07387	ZBTB7A (directAnnotation).
NBPF15	cisbp__M00775	ZBTB1 (inferredBy_Orthology).
NBPF15	kznf__ZNF311_Imbeault2017_RP_ChIP-seq	ZNF311 (directAnnotation).
NBPF15	transfac_pro__M07329	SP7 (directAnnotation).
NBPF15	transfac_pro__M07436	WT1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."