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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: NAPG

Summary for NAPG

Gene information	Gene symbol	NAPG
	Ensembl ID	ENSG00000134265
	Entrez ID	8774
	Gene name	NSF attachment protein gamma
	Synonyms	NA
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: NAPG

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	0.550023	1.49e-03
GSE186960	Panc1 cell line	Cell line	Pancreatic cancer	Pancreatic ductal adenocarcinoma (PDAC)	Chemotherapy	gemcitabine	NA	Malignant cells	-0.36296	5.64e-24
GSE153697	patients	Bone marrow aspirate	Acute lymphoblastic leukemia	Relapsed B-cell acute lymphoblastic leukemia (B-ALL)	Immunotherapy	anti-CD19 CAR-T	NA	Physiology B cells	-0.790077	4.04e-02

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Expression of NAPG in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to NAPG

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating NAPG

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
NAPG	hsa-miR-1277-5p	97.3207	NM_003826
NAPG	hsa-miR-5688	96.6901	NM_003826
NAPG	hsa-miR-495-3p	96.6901	NM_003826
NAPG	hsa-miR-335-3p	96.1752	NM_003826
NAPG	hsa-miR-195-5p	95.7892	NM_003826
NAPG	hsa-miR-15b-5p	95.7892	NM_003826
NAPG	hsa-miR-15a-5p	95.7892	NM_003826
NAPG	hsa-miR-16-5p	95.7441	NM_003826
NAPG	hsa-miR-4303	95.2492	NM_003826
NAPG	hsa-miR-497-5p	95.0987	NM_003826
NAPG	hsa-miR-424-5p	95.0987	NM_003826
NAPG	hsa-miR-6838-5p	95.0987	NM_003826
NAPG	hsa-miR-3148	94.354	NM_003826
NAPG	hsa-miR-4668-5p	91.5838	NM_003826
NAPG	hsa-miR-141-5p	90.2704	NM_003826
NAPG	hsa-miR-664b-5p	89.9602	NM_003826
NAPG	hsa-miR-30d-3p	88.3873	NM_003826
NAPG	hsa-miR-30e-3p	88.3873	NM_003826
NAPG	hsa-miR-30a-3p	88.3873	NM_003826
NAPG	hsa-miR-204-5p	87.9321	NM_003826
NAPG	hsa-miR-211-5p	87.9321	NM_003826
NAPG	hsa-miR-587	86.1307	NM_003826
NAPG	hsa-miR-548aj-3p	84.688	NM_003826
NAPG	hsa-miR-548x-3p	84.688	NM_003826
NAPG	hsa-miR-6832-3p	84.4085	NM_003826
NAPG	hsa-miR-450a-1-3p	83.8967	NM_003826
NAPG	hsa-miR-4425	83.7055	NM_003826
NAPG	hsa-miR-7161-5p	82.7453	NM_003826
NAPG	hsa-miR-6721-5p	82.6222	NM_003826
NAPG	hsa-miR-4506	82.2305	NM_003826
NAPG	hsa-miR-5010-5p	82.0447	NM_003826
NAPG	hsa-miR-4525	82.0447	NM_003826
NAPG	hsa-miR-8087	81.8347	NM_003826
NAPG	hsa-miR-4742-3p	81.6275	NM_003826
NAPG	hsa-miR-548u	81.3326	NM_003826
NAPG	hsa-miR-4661-3p	81.2444	NM_003826
NAPG	hsa-miR-548ae-3p	80.616	NM_003826
NAPG	hsa-miR-548ah-3p	80.616	NM_003826
NAPG	hsa-miR-548aq-3p	80.616	NM_003826
NAPG	hsa-miR-548j-3p	80.616	NM_003826
NAPG	hsa-miR-548am-3p	80.616	NM_003826
NAPG	hsa-miR-499b-5p	80.5318	NM_003826
NAPG	hsa-miR-6837-3p	80.4181	NM_003826
NAPG	hsa-miR-30b-5p	80.1319	NM_003826
NAPG	hsa-miR-30e-5p	80.1319	NM_003826
NAPG	hsa-miR-30a-5p	80.1319	NM_003826
NAPG	hsa-miR-30d-5p	80.1319	NM_003826
NAPG	hsa-miR-30c-5p	80.1319	NM_003826

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Motifs and transcription factors (TFs) regulating NAPG

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
NAPG	metacluster_84.16	RARB (directAnnotation).
NAPG	transfac_pro__M06952	BATF (directAnnotation).
NAPG	transfac_pro__M06959	ZNF425 (directAnnotation).
NAPG	transfac_pro__M06353	ZNF782 (directAnnotation).
NAPG	transfac_pro__M06357	ZNF629 (inferredBy_Orthology).
NAPG	cisbp__M00273	CRX (directAnnotation).
NAPG	transfac_pro__M02919	HNF1A (inferredBy_Orthology).
NAPG	swissregulon__hs__DBP	DBP (directAnnotation).
NAPG	metacluster_84.15	RARB (inferredBy_Orthology).
NAPG	metacluster_191.2	ELK4; NR2C2; NR2C2; NR2C2; NR2C2 (directAnnotation). GABPA (inferredBy_Orthology).
NAPG	metacluster_191.3	EHF; ELF1; ELF1; ELF1; ELF4; ELK1; ELK3; ELK3; ELK4; ELK4; ERF; ETS1; ETS2; ETV3; ETV4; ETV5; FEV; FEV; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; SPDEF; ZNF200 (directAnnotation). ELK1; ELK1; ELK3; ELK3; ELK4; ELK4; ETV1; ETV1; ETV4; ETV4; ETV4; ETV5; GABPA; GABPA (inferredBy_Orthology).
NAPG	metacluster_166.4	BCLAF1; EHF; ELF1; ELF1; ELF1; ELF1; ELF1; ELF1; ELF2; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK3; ELK3; ELK3; ELK3; ELK4; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS1; ETS1; ETS1; ETV1; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV4; ETV4; ETV4; ETV4; ETV5; ETV7; FEV; FEV; FLI1; FLI1; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; GABPB1; GATAD1; PHF20; ZBTB25; ZBTB40 (directAnnotation). EHF; ELF1; ELF1; ELF3; ELF5; ELK3; ELK4; ERG; ETS1; ETV1; ETV2; ETV4; FLI1; GABPA; GABPA (inferredBy_Orthology).
NAPG	taipale_tf_pairs__FOXO1_ELK3_RCCGGAWGTKKW_CAP	ELK3; FOXO1 (directAnnotation).
NAPG	taipale_tf_pairs__MEIS1_ELF1_NTGCCGGAAGTN_CAP_repr	ELF1; MEIS1 (directAnnotation).
NAPG	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
NAPG	transfac_pro__M04826	EP300 (directAnnotation).
NAPG	taipale_cyt_meth__ZNF385D_NCGTCGCGACGN_eDBD_meth	ZNF385D (directAnnotation).
NAPG	hdpi__ETV4	ETV4 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."