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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: NAA30

Summary for NAA30

Gene information	Gene symbol	NAA30
	Ensembl ID	ENSG00000139977
	Entrez ID	122830
	Gene name	N-alpha-acetyltransferase 30, NatC catalytic subunit
	Synonyms	C14orf35\|FLJ35355\|MAK3\|Mak3p\|NAT12
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: NAA30

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.355651	5.14e-42

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Expression of NAA30 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to NAA30

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating NAA30

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
NAA30	hsa-miR-607	99.0305	NM_001011713
NAA30	hsa-miR-3671	98.9599	NM_001011713
NAA30	hsa-miR-4282	98.892	NM_001011713
NAA30	hsa-miR-5011-3p	98.631	NM_001011713
NAA30	hsa-miR-651-3p	97.8983	NM_001011713
NAA30	hsa-miR-4291	97.377	NM_001011713
NAA30	hsa-miR-518a-5p	96.9928	NM_001011713
NAA30	hsa-miR-527	96.9928	NM_001011713
NAA30	hsa-miR-3658	96.8867	NM_001011713
NAA30	hsa-miR-3124-3p	96.1985	NM_001011713
NAA30	hsa-miR-6868-5p	95.6724	NM_001011713
NAA30	hsa-miR-5692a	95.6584	NM_001011713
NAA30	hsa-miR-32-3p	95.2988	NM_001011713
NAA30	hsa-miR-4272	94.9575	NM_001011713
NAA30	hsa-miR-4679	94.8458	NM_001011713
NAA30	hsa-miR-6885-3p	94.7709	NM_001011713
NAA30	hsa-miR-922	94.5491	NM_001011713
NAA30	hsa-miR-12120	94.402	NM_001011713
NAA30	hsa-miR-548c-3p	94.3762	NM_001011713
NAA30	hsa-miR-3133	94.3555	NM_001011713
NAA30	hsa-miR-519c-3p	93.6547	NM_001011713
NAA30	hsa-miR-519a-3p	93.6547	NM_001011713
NAA30	hsa-miR-519b-3p	93.6547	NM_001011713
NAA30	hsa-miR-3119	93.6034	NM_001011713
NAA30	hsa-miR-3163	93.4109	NM_001011713
NAA30	hsa-miR-4666b	92.7649	NM_001011713
NAA30	hsa-miR-7844-5p	92.6101	NM_001011713
NAA30	hsa-miR-7110-3p	92.3743	NM_001011713
NAA30	hsa-miR-3662	92.2197	NM_001011713
NAA30	hsa-miR-203a-3p	92.1075	NM_001011713
NAA30	hsa-miR-3688-3p	91.9267	NM_001011713
NAA30	hsa-miR-6818-5p	91.1863	NM_001011713
NAA30	hsa-miR-4477b	90.6495	NM_001011713
NAA30	hsa-miR-1263	90.6099	NM_001011713
NAA30	hsa-miR-5195-3p	90.5739	NM_001011713
NAA30	hsa-miR-145-5p	90.5739	NM_001011713
NAA30	hsa-miR-646	90.2806	NM_001011713
NAA30	hsa-miR-152-5p	90.12	NM_001011713
NAA30	hsa-miR-3622b-3p	89.8903	NM_001011713
NAA30	hsa-miR-3622a-3p	89.8903	NM_001011713
NAA30	hsa-miR-106a-5p	89.5739	NM_001011713
NAA30	hsa-miR-526b-3p	89.5739	NM_001011713
NAA30	hsa-miR-20a-5p	89.5739	NM_001011713
NAA30	hsa-miR-106b-5p	89.5739	NM_001011713
NAA30	hsa-miR-584-5p	89.3076	NM_001011713
NAA30	hsa-miR-1827	88.5734	NM_001011713
NAA30	hsa-miR-558	88.5488	NM_001011713
NAA30	hsa-miR-3613-3p	88.4105	NM_001011713
NAA30	hsa-miR-6074	88.3596	NM_001011713
NAA30	hsa-miR-205-5p	88.0995	NM_001011713

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Motifs and transcription factors (TFs) regulating NAA30

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
NAA30	metacluster_144.3	ZNF704; ZNF704 (directAnnotation).
NAA30	metacluster_7.13	ZFX (directAnnotation).
NAA30	kznf__ZNF730_Imbeault2017_RP_RCADE	ZNF730 (directAnnotation).
NAA30	cisbp__M00968	MTF2 (directAnnotation).
NAA30	metacluster_155.23	BCL11B; ZNF711; ZNF711 (directAnnotation). ZFY (inferredBy_Orthology).
NAA30	metacluster_160.20	JUND; PRDM15 (directAnnotation).
NAA30	cisbp__M00341	PAX6 (directAnnotation).
NAA30	metacluster_141.5	NR3C1; THAP1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY2; YY2; ZNF597 (directAnnotation). YY1; YY1; YY1; YY2; ZFP42 (inferredBy_Orthology).
NAA30	metacluster_151.1	KAT7; PML; SMAD5; TAF1; ZFP37; ZGPAT; ZNF519; ZNF519; ZNF571; ZNF770; ZNF770; ZNF770; ZSCAN22; ZSCAN22 (directAnnotation).
NAA30	metacluster_61.1	DEAF1; DEAF1 (directAnnotation).
NAA30	cisbp__M00788	ZFY (inferredBy_Orthology).
NAA30	kznf__ZNF213_Schmitges2016_RCADE	ZNF213 (directAnnotation).
NAA30	hdpi__ZNF304	ZNF304 (directAnnotation).
NAA30	transfac_pro__M02844	BCL6B (inferredBy_Orthology).
NAA30	metacluster_125.2	TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2D; TFAP2D; TFAP2D; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; ZNF611; ZNF611 (directAnnotation). TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E (inferredBy_Orthology).
NAA30	metacluster_133.1	ZNF304; ZNF304; ZSCAN22 (directAnnotation).
NAA30	transfac_pro__M01199	TRIM28 (directAnnotation).
NAA30	kznf__ZNF682_Isakova2017_SMiLE-seq	ZNF682 (directAnnotation).
NAA30	metacluster_151.2	ZNF23 (directAnnotation).
NAA30	transfac_pro__M01219	SP1 (directAnnotation). SP3 (inferredBy_Orthology).
NAA30	transfac_pro__M03806	ZBTB7C (directAnnotation).
NAA30	transfac_pro__M00915	TFAP2A; TFAP2B; TFAP2C (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."