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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: NAA25

Summary for NAA25

Gene information	Gene symbol	NAA25
	Ensembl ID	ENSG00000111300
	Entrez ID	80018
	Gene name	N-alpha-acetyltransferase 25, NatB auxiliary subunit
	Synonyms	C12orf30\|FLJ13089
	Gene type	protein_coding
	UniProtAcc	Q14CX7

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Dataset with differentially expressed gene: NAA25

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE186960	Panc1 cell line	Cell line	Pancreatic cancer	Pancreatic ductal adenocarcinoma (PDAC)	Chemotherapy	gemcitabine	NA	Malignant cells	-0.390856	3.02e-23

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Expression of NAA25 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to NAA25

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating NAA25

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
NAA25	hsa-miR-190a-3p	100	NM_024953
NAA25	hsa-miR-5011-5p	100	NM_024953
NAA25	hsa-miR-3662	98.9456	NM_024953
NAA25	hsa-miR-3646	98.5242	NM_024953
NAA25	hsa-miR-3129-5p	98.4501	NM_024953
NAA25	hsa-miR-199a-3p	98.4501	NM_024953
NAA25	hsa-miR-199b-3p	98.4501	NM_024953
NAA25	hsa-miR-4666a-3p	95.7409	NM_024953
NAA25	hsa-miR-6894-3p	95.1124	NM_024953
NAA25	hsa-miR-6839-5p	94.5922	NM_024953
NAA25	hsa-miR-15a-5p	94.4436	NM_024953
NAA25	hsa-miR-1305	94.4015	NM_024953
NAA25	hsa-miR-12136	94.2473	NM_024953
NAA25	hsa-miR-4698	94.1324	NM_024953
NAA25	hsa-miR-378j	93.9827	NM_024953
NAA25	hsa-miR-4641	93.8467	NM_024953
NAA25	hsa-miR-548e-5p	93.016	NM_024953
NAA25	hsa-miR-1468-3p	92.941	NM_024953
NAA25	hsa-miR-29b-1-5p	92.6263	NM_024953
NAA25	hsa-let-7f-1-3p	92.6232	NM_024953
NAA25	hsa-let-7b-3p	92.6232	NM_024953
NAA25	hsa-miR-98-3p	92.6232	NM_024953
NAA25	hsa-let-7a-3p	92.6232	NM_024953
NAA25	hsa-miR-221-3p	92.2251	NM_024953
NAA25	hsa-miR-222-3p	92.2251	NM_024953
NAA25	hsa-miR-195-5p	92.1439	NM_024953
NAA25	hsa-miR-15b-5p	92.1439	NM_024953
NAA25	hsa-miR-16-5p	92.1439	NM_024953
NAA25	hsa-miR-6838-5p	92.1439	NM_024953
NAA25	hsa-miR-4782-5p	91.0027	NM_024953
NAA25	hsa-miR-5706	91.0027	NM_024953
NAA25	hsa-miR-4797-3p	90.7582	NM_024953
NAA25	hsa-miR-30b-5p	90.3246	NM_024953
NAA25	hsa-miR-30e-5p	90.3246	NM_024953
NAA25	hsa-miR-30d-5p	90.3246	NM_024953
NAA25	hsa-miR-30a-5p	90.3246	NM_024953
NAA25	hsa-miR-30c-5p	90.3246	NM_024953
NAA25	hsa-miR-936	90.2616	NM_024953
NAA25	hsa-miR-424-5p	89.8439	NM_024953
NAA25	hsa-miR-497-5p	89.8439	NM_024953
NAA25	hsa-miR-661	89.123	NM_024953
NAA25	hsa-miR-4482-3p	87.7457	NM_024953
NAA25	hsa-miR-338-5p	85.6648	NM_024953
NAA25	hsa-miR-4773	85.649	NM_024953
NAA25	hsa-miR-6507-5p	85.2315	NM_024953
NAA25	hsa-miR-203a-3p	85.1897	NM_024953
NAA25	hsa-miR-335-5p	84.8907	NM_024953
NAA25	hsa-miR-1299	84.7917	NM_024953
NAA25	hsa-miR-337-3p	84.4814	NM_024953
NAA25	hsa-miR-33a-3p	84.3952	NM_024953

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Motifs and transcription factors (TFs) regulating NAA25

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
NAA25	taipale_cyt_meth__ZNF385D_NCGTCGCGACGN_eDBD_meth	ZNF385D (directAnnotation).
NAA25	taipale_tf_pairs__E2F1_ELK1_SGCGCNNNNNCGGAAGN_CAP_repr	E2F1; ELK1 (directAnnotation).
NAA25	metacluster_182.10	ZFX (directAnnotation).
NAA25	transfac_pro__M06173	ZNF85 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."