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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: MYO1D

Summary for MYO1D

Gene information	Gene symbol	MYO1D
	Ensembl ID	ENSG00000176658
	Entrez ID	4642
	Gene name	myosin ID
	Synonyms	KIAA0727\|myr4\|PPP1R108
	Gene type	protein_coding
	UniProtAcc	O94832

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Dataset with differentially expressed gene: MYO1D

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE169246_PacBlood	patients	Peripheral blood mononuclear cells	Breast cancer	Advanced triple-negative breast cancer (TNBC)	Chemotherapy	paclitaxel	pre	Plasma cells	0.357748	9.14e-04

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Expression of MYO1D in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to MYO1D

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating MYO1D

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
MYO1D	hsa-miR-4639-5p	95.3157	NM_001303279
MYO1D	hsa-miR-4747-5p	94.6845	NM_015194
MYO1D	hsa-miR-5196-5p	94.6845	NM_015194
MYO1D	hsa-miR-3915	94.3922	NM_015194
MYO1D	hsa-miR-182-5p	94.2273	NM_015194
MYO1D	hsa-miR-137-3p	93.8628	NM_015194
MYO1D	hsa-miR-3671	93.1299	NM_001303279
MYO1D	hsa-miR-4470	93.0676	NM_015194
MYO1D	hsa-miR-3157-5p	92.8102	NM_001303280
MYO1D	hsa-miR-2861	92.7881	NM_001303279
MYO1D	hsa-miR-3650	92.7141	NM_015194
MYO1D	hsa-miR-12118	92.5302	NM_001303280
MYO1D	hsa-miR-6891-5p	92.5302	NM_001303280
MYO1D	hsa-miR-3173-3p	92.5302	NM_001303280
MYO1D	hsa-miR-3149	92.2589	NM_001303279
MYO1D	hsa-miR-544a	92.1728	NM_001303279
MYO1D	hsa-miR-567	90.699	NM_001303279
MYO1D	hsa-miR-3942-3p	90.2199	NM_001303279
MYO1D	hsa-miR-380-5p	90.1009	NM_015194
MYO1D	hsa-miR-6814-5p	90.0294	NM_015194
MYO1D	hsa-miR-409-3p	89.906	NM_001303279
MYO1D	hsa-miR-5190	89.5926	NM_015194
MYO1D	hsa-miR-548at-5p	89.3535	NM_015194
MYO1D	hsa-miR-297	89.3466	NM_001303279
MYO1D	hsa-miR-1324	88.2751	NM_001303280
MYO1D	hsa-miR-155-5p	87.8282	NM_015194
MYO1D	hsa-miR-1283	87.8085	NM_001303280
MYO1D	hsa-miR-4283	87.3796	NM_015194
MYO1D	hsa-miR-6847-5p	87.2382	NM_015194
MYO1D	hsa-miR-563	86.3842	NM_015194
MYO1D	hsa-miR-766-5p	85.694	NM_001303280
MYO1D	hsa-miR-551b-5p	85.469	NM_015194
MYO1D	hsa-miR-3150b-3p	85.3247	NM_001303280
MYO1D	hsa-miR-4784	85.3247	NM_001303280
MYO1D	hsa-miR-3618	84.5205	NM_001303280
MYO1D	hsa-miR-4505	84.1314	NM_015194
MYO1D	hsa-miR-5787	84.1314	NM_015194
MYO1D	hsa-miR-5590-3p	84.0385	NM_001303280
MYO1D	hsa-miR-3192-5p	83.8195	NM_015194
MYO1D	hsa-miR-142-5p	83.646	NM_001303280
MYO1D	hsa-miR-3619-5p	83.6033	NM_015194
MYO1D	hsa-miR-214-3p	82.7104	NM_015194
MYO1D	hsa-miR-3692-5p	82.6381	NM_015194
MYO1D	hsa-miR-4503	81.8307	NM_015194
MYO1D	hsa-miR-4531	81.3781	NM_015194
MYO1D	hsa-miR-4307	81.3271	NM_001303279
MYO1D	hsa-miR-1910-3p	80.7434	NM_015194
MYO1D	hsa-miR-7106-5p	80.3811	NM_015194
MYO1D	hsa-miR-761	80.0116	NM_015194

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Motifs and transcription factors (TFs) regulating MYO1D

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
MYO1D	transfac_pro__M05718	ZNF30 (directAnnotation).
MYO1D	metacluster_7.7	SP2 (directAnnotation). KLF16 (inferredBy_Orthology).
MYO1D	taipale_cyt_meth__NKX2-3_NTCGTTGAN_eDBD_meth	NKX2-3 (directAnnotation).
MYO1D	transfac_pro__M06649	ZNF442 (directAnnotation).
MYO1D	transfac_pro__M06301	ZNF404 (directAnnotation).
MYO1D	taipale_cyt_meth__DMRTC2_GAACGATACA_FL	DMRTC2 (directAnnotation).
MYO1D	taipale_tf_pairs__ETV2_EOMES_RCCGGANNNNNNNNNNNACACCTN_CAP_repr	EOMES; ETV2 (directAnnotation).
MYO1D	transfac_pro__M06569	ZNF775 (directAnnotation).
MYO1D	transfac_pro__M05449	ZNF414 (inferredBy_Orthology).
MYO1D	taipale_cyt_meth__DMRTC2_RAACGATACA_eDBD_repr	DMRTC2 (directAnnotation).
MYO1D	metacluster_172.7	GTF3A (directAnnotation).
MYO1D	taipale_tf_pairs__ETV2_TBX21_RCCGGANNNNNNNNNNNACACCTN_CAP	ETV2; TBX21 (directAnnotation).
MYO1D	taipale_cyt_meth__ELF3_NATKGCGGATGYN_eDBD_repr	ELF3 (directAnnotation).
MYO1D	nitta__Ets98B_TTCCCC20NTA_KH_TKGCGGATGCN_m1_c3	SPDEF (inferredBy_Orthology).
MYO1D	metacluster_172.27	DMRTC2 (directAnnotation).
MYO1D	hocomoco__TGIF2_HUMAN.H11MO.0.D	TGIF2 (directAnnotation).
MYO1D	dbtfbs__E2F8_representative_N1	E2F8 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."