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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: MTMR10

Summary for MTMR10

Gene information	Gene symbol	MTMR10
	Ensembl ID	ENSG00000277086
	Entrez ID	54893
	Gene name	myotubularin related protein 10
	Synonyms	FLJ20313
	Gene type	protein_coding
	UniProtAcc	Q9NXD2

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Dataset with differentially expressed gene: MTMR10

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE153697	patients	Bone marrow aspirate	Acute lymphoblastic leukemia	Relapsed B-cell acute lymphoblastic leukemia (B-ALL)	Immunotherapy	anti-CD19 CAR-T	NA	Malignant cells	-0.491548	4.29e-38

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Expression of MTMR10 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to MTMR10

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating MTMR10

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
MTMR10	hsa-miR-548at-5p	98.5353	NM_017762
MTMR10	hsa-miR-142-5p	98.4555	NM_017762
MTMR10	hsa-miR-5590-3p	98.4428	NM_017762
MTMR10	hsa-miR-196a-1-3p	97.2979	NM_017762
MTMR10	hsa-miR-4423-3p	97.0134	NM_017762
MTMR10	hsa-miR-552-5p	96.349	NM_017762
MTMR10	hsa-miR-5582-5p	95.1074	NM_017762
MTMR10	hsa-miR-29b-2-5p	95.0836	NM_017762
MTMR10	hsa-miR-6847-5p	94.7093	NM_017762
MTMR10	hsa-miR-8063	94.5712	NM_017762
MTMR10	hsa-miR-3182	93.2114	NM_017762
MTMR10	hsa-miR-4671-3p	93.115	NM_017762
MTMR10	hsa-miR-12135	92.3485	NM_017762
MTMR10	hsa-miR-6884-3p	90.5118	NM_017762
MTMR10	hsa-miR-3908	90.4074	NM_017762
MTMR10	hsa-miR-454-3p	90.3835	NM_017762
MTMR10	hsa-miR-449a	89.9428	NM_017762
MTMR10	hsa-miR-34a-5p	89.9428	NM_017762
MTMR10	hsa-miR-646	89.3654	NM_017762
MTMR10	hsa-miR-595	89.1852	NM_017762
MTMR10	hsa-miR-590-3p	88.1091	NM_017762
MTMR10	hsa-miR-130a-3p	87.9648	NM_017762
MTMR10	hsa-miR-301b-3p	87.9648	NM_017762
MTMR10	hsa-miR-301a-3p	87.9648	NM_017762
MTMR10	hsa-miR-3666	87.9648	NM_017762
MTMR10	hsa-miR-4295	87.9648	NM_017762
MTMR10	hsa-miR-130b-3p	87.9648	NM_017762
MTMR10	hsa-miR-148a-3p	87.247	NM_017762
MTMR10	hsa-miR-148b-3p	87.247	NM_017762
MTMR10	hsa-miR-152-3p	87.247	NM_017762
MTMR10	hsa-miR-34c-5p	86.8972	NM_017762
MTMR10	hsa-miR-449b-5p	86.8972	NM_017762
MTMR10	hsa-miR-335-3p	86.7353	NM_017762
MTMR10	hsa-miR-124-3p	86.7095	NM_017762
MTMR10	hsa-miR-506-3p	86.7095	NM_017762
MTMR10	hsa-miR-3609	86.4725	NM_017762
MTMR10	hsa-miR-548ah-5p	86.4725	NM_017762
MTMR10	hsa-miR-653-5p	86.3688	NM_017762
MTMR10	hsa-miR-4698	86.1657	NM_017762
MTMR10	hsa-miR-633	86.1451	NM_017762
MTMR10	hsa-miR-624-5p	85.4522	NM_017762
MTMR10	hsa-miR-548t-5p	85.3773	NM_017762
MTMR10	hsa-miR-548az-5p	85.3773	NM_017762
MTMR10	hsa-miR-3622a-5p	85.1777	NM_017762
MTMR10	hsa-miR-3148	84.7551	NM_017762
MTMR10	hsa-miR-607	84.7248	NM_017762
MTMR10	hsa-miR-5591-3p	84.1812	NM_017762
MTMR10	hsa-miR-4703-5p	83.6877	NM_017762
MTMR10	hsa-miR-548an	83.6849	NM_017762
MTMR10	hsa-miR-340-5p	83.5968	NM_017762

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Motifs and transcription factors (TFs) regulating MTMR10

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
MTMR10	metacluster_7.5	PLAGL1; PLAGL1 (directAnnotation).
MTMR10	transfac_pro__M01783	SP2 (directAnnotation).
MTMR10	metacluster_144.8	ZNF30; ZNF30 (directAnnotation).
MTMR10	metacluster_155.23	BCL11B; ZNF711; ZNF711 (directAnnotation). ZFY (inferredBy_Orthology).
MTMR10	cisbp__M00341	PAX6 (directAnnotation).
MTMR10	transfac_pro__M01253	CNOT3 (directAnnotation).
MTMR10	homer__TWVGGTCCGC_HINFP	HINFP (directAnnotation).
MTMR10	metacluster_7.13	ZFX (directAnnotation).
MTMR10	cisbp__M00968	MTF2 (directAnnotation).
MTMR10	transfac_pro__M04817	ZBTB33 (directAnnotation).
MTMR10	transfac_pro__M00803	E2F1; E2F3; E2F4; TFDP1 (directAnnotation).
MTMR10	transfac_pro__M02089	E2F3 (directAnnotation).
MTMR10	jaspar__MA0748.2	YY2 (directAnnotation).
MTMR10	dbtfbs__ZBTB8A_HEK293_ENCSR481FEC_merged_N1	ZBTB8A (directAnnotation).
MTMR10	kznf__ZNF548_Imbeault2017_RP_RCADE	ZNF548 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."