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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: MORN4

Summary for MORN4

Gene information	Gene symbol	MORN4
	Ensembl ID	ENSG00000171160
	Entrez ID	118812
	Gene name	MORN repeat containing 4
	Synonyms	bA548K23.4\|C10orf83\|FLJ25925\|rtp
	Gene type	protein_coding
	UniProtAcc	Q8NDC4

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Dataset with differentially expressed gene: MORN4

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	0.907954	7.68e-06

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Expression of MORN4 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to MORN4

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating MORN4

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
MORN4	hsa-miR-371b-5p	94.2582	NM_001098831
MORN4	hsa-miR-373-5p	94.2582	NM_001098831
MORN4	hsa-miR-616-5p	94.2582	NM_001098831
MORN4	hsa-miR-7150	92.9079	NM_001098831
MORN4	hsa-miR-101-3p	91.4784	NM_001098831
MORN4	hsa-miR-139-5p	91.1437	NM_001098831
MORN4	hsa-miR-4719	90.8518	NM_001098831
MORN4	hsa-miR-6866-5p	88.5637	NM_001098831
MORN4	hsa-miR-4316	87.9821	NM_001098831
MORN4	hsa-miR-29a-5p	87.8972	NM_001098831
MORN4	hsa-miR-4433b-5p	87.8327	NM_001098831
MORN4	hsa-miR-5582-5p	87.6666	NM_001098831
MORN4	hsa-miR-548au-3p	87.6574	NM_001098831
MORN4	hsa-miR-6740-3p	84.5229	NM_001098831
MORN4	hsa-miR-6808-5p	84.5067	NM_001098831
MORN4	hsa-miR-6893-5p	84.5067	NM_001098831
MORN4	hsa-miR-940	84.4749	NM_001098831
MORN4	hsa-miR-3919	83.8119	NM_001098831
MORN4	hsa-miR-374b-5p	83.6102	NM_001098831
MORN4	hsa-miR-579-3p	83.0938	NM_001098831
MORN4	hsa-miR-664b-3p	83.0938	NM_001098831
MORN4	hsa-miR-374a-5p	82.965	NM_001098831
MORN4	hsa-miR-6071	82.8232	NM_001098831
MORN4	hsa-miR-4686	81.0436	NM_001098831
MORN4	hsa-miR-4299	80.9595	NM_001098831

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Motifs and transcription factors (TFs) regulating MORN4

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
MORN4	transfac_pro__M04617	ZBTB7A (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."