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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: MFAP5

Summary for MFAP5

Gene information	Gene symbol	MFAP5
	Ensembl ID	ENSG00000197614
	Entrez ID	8076
	Gene name	microfibril associated protein 5
	Synonyms	MAGP2\|MP25
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: MFAP5

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-5.09626	5.06e-03

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Expression of MFAP5 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to MFAP5

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating MFAP5

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
MFAP5	hsa-miR-5011-5p	99.9304	NM_001297709
MFAP5	hsa-miR-1324	99.4574	NM_001297709
MFAP5	hsa-miR-1252-3p	96.9576	NM_001297709
MFAP5	hsa-miR-545-3p	96.0444	NM_001297709
MFAP5	hsa-miR-3119	95.6412	NM_001297709
MFAP5	hsa-miR-1262	95.5841	NM_001297709
MFAP5	hsa-miR-190a-3p	95.2399	NM_001297709
MFAP5	hsa-miR-4711-3p	95.0071	NM_001297709
MFAP5	hsa-miR-1277-5p	94.6841	NM_001297709
MFAP5	hsa-miR-4701-3p	94.5297	NM_001297709
MFAP5	hsa-miR-6736-5p	94.5297	NM_001297709
MFAP5	hsa-miR-302e	92.7318	NM_001297709
MFAP5	hsa-miR-433-3p	92.1311	NM_001297709
MFAP5	hsa-miR-4755-3p	90.2128	NM_001297709
MFAP5	hsa-miR-200b-3p	88.7475	NM_001297709
MFAP5	hsa-miR-429	88.7475	NM_001297709
MFAP5	hsa-miR-200c-3p	88.7475	NM_001297709
MFAP5	hsa-miR-6731-3p	88.6391	NM_001297709
MFAP5	hsa-miR-5692b	87.9488	NM_001297709
MFAP5	hsa-miR-5692c	87.9488	NM_001297709
MFAP5	hsa-miR-302c-3p	87.7818	NM_001297709
MFAP5	hsa-miR-302a-3p	87.7818	NM_001297709
MFAP5	hsa-miR-302d-3p	87.7818	NM_001297709
MFAP5	hsa-miR-302b-3p	87.7818	NM_001297709
MFAP5	hsa-miR-3148	87.5983	NM_001297709
MFAP5	hsa-miR-493-5p	86.3821	NM_001297709
MFAP5	hsa-miR-539-5p	85.8422	NM_001297709
MFAP5	hsa-miR-520a-3p	84.9839	NM_001297709
MFAP5	hsa-miR-520e-3p	84.9839	NM_001297709
MFAP5	hsa-miR-373-3p	84.9839	NM_001297709
MFAP5	hsa-miR-520d-3p	84.9839	NM_001297709
MFAP5	hsa-miR-520c-3p	84.9839	NM_001297709
MFAP5	hsa-miR-520b-3p	84.9839	NM_001297709
MFAP5	hsa-miR-372-3p	84.9839	NM_001297709
MFAP5	hsa-miR-410-3p	83.529	NM_001297709
MFAP5	hsa-miR-586	81.9248	NM_001297709
MFAP5	hsa-miR-5700	81.5115	NM_001297709
MFAP5	hsa-miR-6858-3p	81.3591	NM_001297709
MFAP5	hsa-miR-3156-5p	80.3485	NM_001297709
MFAP5	hsa-miR-4780	80.3455	NM_001297709

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Motifs and transcription factors (TFs) regulating MFAP5

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."