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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: MAB21L1

Summary for MAB21L1

Gene information	Gene symbol	MAB21L1
	Ensembl ID	ENSG00000180660
	Entrez ID	4081
	Gene name	mab-21 like 1
	Synonyms	CAGR1
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: MAB21L1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	-0.468381	0.00e+00

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Expression of MAB21L1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to MAB21L1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating MAB21L1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
MAB21L1	hsa-miR-607	99.8814	NM_005584
MAB21L1	hsa-miR-4698	98.9855	NM_005584
MAB21L1	hsa-miR-498-5p	98.7044	NM_005584
MAB21L1	hsa-miR-1297	98.2502	NM_005584
MAB21L1	hsa-miR-26b-5p	97.609	NM_005584
MAB21L1	hsa-miR-26a-5p	97.609	NM_005584
MAB21L1	hsa-miR-4465	96.4012	NM_005584
MAB21L1	hsa-miR-1305	95.178	NM_005584
MAB21L1	hsa-miR-510-3p	95.0449	NM_005584
MAB21L1	hsa-miR-500a-5p	94.8153	NM_005584
MAB21L1	hsa-miR-30b-5p	93.8486	NM_005584
MAB21L1	hsa-miR-30e-5p	93.8486	NM_005584
MAB21L1	hsa-miR-30c-5p	93.8486	NM_005584
MAB21L1	hsa-miR-30d-5p	93.8486	NM_005584
MAB21L1	hsa-miR-30a-5p	93.8486	NM_005584
MAB21L1	hsa-miR-199a-5p	93.2303	NM_005584
MAB21L1	hsa-miR-199b-5p	93.2303	NM_005584
MAB21L1	hsa-miR-3671	92.7582	NM_005584
MAB21L1	hsa-miR-410-3p	92.6414	NM_005584
MAB21L1	hsa-miR-1277-5p	92.4595	NM_005584
MAB21L1	hsa-miR-5011-5p	92.3867	NM_005584
MAB21L1	hsa-miR-6801-5p	92.1923	NM_005584
MAB21L1	hsa-miR-10393-3p	92.1923	NM_005584
MAB21L1	hsa-miR-8063	91.7886	NM_005584
MAB21L1	hsa-miR-206	90.4795	NM_005584
MAB21L1	hsa-miR-1-3p	90.4795	NM_005584
MAB21L1	hsa-miR-4719	90.0913	NM_005584
MAB21L1	hsa-miR-6741-3p	89.6661	NM_005584
MAB21L1	hsa-miR-3942-3p	89.0153	NM_005584
MAB21L1	hsa-miR-5697	88.9792	NM_005584
MAB21L1	hsa-miR-6513-3p	88.6533	NM_005584
MAB21L1	hsa-miR-613	88.4395	NM_005584
MAB21L1	hsa-miR-7856-5p	88.1385	NM_005584
MAB21L1	hsa-miR-5003-3p	87.5042	NM_005584
MAB21L1	hsa-miR-556-3p	87.3057	NM_005584
MAB21L1	hsa-miR-551b-5p	86.8291	NM_005584
MAB21L1	hsa-miR-5692a	86.7241	NM_005584
MAB21L1	hsa-miR-4729	86.6125	NM_005584
MAB21L1	hsa-miR-4496	86.1618	NM_005584
MAB21L1	hsa-miR-143-3p	85.519	NM_005584
MAB21L1	hsa-miR-4770	85.519	NM_005584
MAB21L1	hsa-miR-6780a-3p	85.1028	NM_005584
MAB21L1	hsa-miR-5696	83.8408	NM_005584
MAB21L1	hsa-miR-4477b	83.7948	NM_005584
MAB21L1	hsa-miR-6770-5p	83.4906	NM_005584
MAB21L1	hsa-miR-320e	83.2192	NM_005584
MAB21L1	hsa-miR-6088	83.1017	NM_005584
MAB21L1	hsa-miR-4495	82.8784	NM_005584
MAB21L1	hsa-miR-4680-3p	82.3222	NM_005584
MAB21L1	hsa-miR-519b-3p	82.0313	NM_005584

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Motifs and transcription factors (TFs) regulating MAB21L1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."