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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: KIF26B

Summary for KIF26B

Gene informationGene symbol

KIF26B

Ensembl ID

ENSG00000281216

Entrez ID

55083

Gene namekinesin family member 26B
SynonymsFLJ10157
Gene typeprotein_coding
UniProtAcc

NA


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Dataset with differentially expressed gene: KIF26B

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE115251

Kelly cell lineCell lineNeuroblastomaNeuroblastomaTargeted therapyTAE684NAMalignant cells-0.5724340.00e+00

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Expression of KIF26B in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to KIF26B

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating KIF26B

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
KIF26Bhsa-miR-126194.0872NM_018012
KIF26Bhsa-miR-6740-5p93.9506NM_018012
KIF26Bhsa-miR-4708-3p93.6554NM_018012
KIF26Bhsa-miR-570-3p93.2673NM_018012
KIF26Bhsa-miR-33a-3p92.8778NM_018012
KIF26Bhsa-miR-5004-3p92.3355NM_018012
KIF26Bhsa-miR-432691.9705NM_018012
KIF26Bhsa-miR-480190.7738NM_018012
KIF26Bhsa-miR-29a-3p90.5396NM_018012
KIF26Bhsa-miR-29b-3p90.5396NM_018012
KIF26Bhsa-miR-29c-3p90.5396NM_018012
KIF26Bhsa-miR-4731-3p90.0098NM_018012
KIF26Bhsa-miR-368589.4691NM_018012
KIF26Bhsa-miR-520f-3p89.1554NM_018012
KIF26Bhsa-miR-5196-3p88.3978NM_018012
KIF26Bhsa-miR-302e88.3925NM_018012
KIF26Bhsa-miR-520e-3p86.886NM_018012
KIF26Bhsa-miR-373-3p86.886NM_018012
KIF26Bhsa-miR-302d-3p86.886NM_018012
KIF26Bhsa-miR-302b-3p86.886NM_018012
KIF26Bhsa-miR-302a-3p86.886NM_018012
KIF26Bhsa-miR-520d-3p86.886NM_018012
KIF26Bhsa-miR-520a-3p86.886NM_018012
KIF26Bhsa-miR-520b-3p86.886NM_018012
KIF26Bhsa-miR-302c-3p86.886NM_018012
KIF26Bhsa-miR-372-3p86.886NM_018012
KIF26Bhsa-miR-520c-3p86.886NM_018012
KIF26Bhsa-miR-506-3p86.1829NM_018012
KIF26Bhsa-miR-124-3p86.1829NM_018012
KIF26Bhsa-miR-568285.7868NM_018012
KIF26Bhsa-miR-526b-3p85.2713NM_018012
KIF26Bhsa-miR-106b-5p85.2713NM_018012
KIF26Bhsa-miR-20a-5p85.2713NM_018012
KIF26Bhsa-miR-106a-5p85.2713NM_018012
KIF26Bhsa-miR-767-5p84.9469NM_018012
KIF26Bhsa-miR-520g-3p84.455NM_018012
KIF26Bhsa-miR-520h84.455NM_018012
KIF26Bhsa-miR-155-3p84.2918NM_018012
KIF26Bhsa-miR-519d-3p81.9103NM_018012
KIF26Bhsa-miR-20b-5p81.9103NM_018012
KIF26Bhsa-miR-93-5p81.9103NM_018012
KIF26Bhsa-miR-17-5p81.9103NM_018012
KIF26Bhsa-miR-806881.2173NM_018012
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Motifs and transcription factors (TFs) regulating KIF26B

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."