Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: KIDINS220

Summary for KIDINS220

Gene information	Gene symbol	KIDINS220
	Ensembl ID	ENSG00000134313
	Entrez ID	57498
	Gene name	kinase D interacting substrate 220
	Synonyms	ARMS
	Gene type	protein_coding
	UniProtAcc	NA

Top

Dataset with differentially expressed gene: KIDINS220

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE131984_JQ1Pal	SUM159 cell line	Cell line	Breast cancer	Triple-negative breast cancer (TNBC)	Targeted therapy	JQ1 + palbociclib	NA	Malignant cells	0.356816	6.44e-24

Top

Expression of KIDINS220 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to KIDINS220

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating KIDINS220

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
KIDINS220	hsa-miR-5011-5p	98.1845	NM_020738
KIDINS220	hsa-miR-215-3p	96.5565	NM_020738
KIDINS220	hsa-miR-450b-5p	93.6672	NM_020738
KIDINS220	hsa-miR-144-3p	93.0418	NM_020738
KIDINS220	hsa-miR-34a-3p	92.1673	NM_020738
KIDINS220	hsa-miR-190a-3p	91.8525	NM_020738
KIDINS220	hsa-miR-5702	91.5061	NM_020738
KIDINS220	hsa-miR-6747-3p	88.2452	NM_020738
KIDINS220	hsa-miR-200a-3p	88.2022	NM_020738
KIDINS220	hsa-miR-141-3p	88.2022	NM_020738
KIDINS220	hsa-miR-3622b-3p	88.1124	NM_020738
KIDINS220	hsa-miR-3622a-3p	88.1124	NM_020738
KIDINS220	hsa-miR-7113-3p	87.8374	NM_020738
KIDINS220	hsa-miR-4698	86.9894	NM_020738
KIDINS220	hsa-miR-4306	84.842	NM_020738
KIDINS220	hsa-miR-545-3p	84.8252	NM_020738
KIDINS220	hsa-miR-4743-3p	84.3948	NM_020738
KIDINS220	hsa-miR-513b-3p	84.1517	NM_020738
KIDINS220	hsa-miR-593-3p	82.2689	NM_020738
KIDINS220	hsa-miR-146a-3p	81.78	NM_020738
KIDINS220	hsa-miR-6730-5p	81.5302	NM_020738
KIDINS220	hsa-miR-6773-3p	80.8967	NM_020738

Page: 1

Top

Motifs and transcription factors (TFs) regulating KIDINS220

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."