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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: FKBP14

Summary for FKBP14

Gene information	Gene symbol	FKBP14
	Ensembl ID	ENSG00000106080
	Entrez ID	55033
	Gene name	FKBP prolyl isomerase 14
	Synonyms	FKBP22\|FLJ20731
	Gene type	protein_coding
	UniProtAcc	Q9NWM8

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Dataset with differentially expressed gene: FKBP14

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	0.607365	4.97e-02
GSE168668	LNCaP cell line	Cell line	Prostate cancer	Prostate cancer	Targeted therapy	enzalutamide	NA	Malignant cells	-0.292328	0.00e+00

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Expression of FKBP14 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to FKBP14

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating FKBP14

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
FKBP14	hsa-miR-5011-5p	100	NM_017946
FKBP14	hsa-miR-190a-3p	99.9989	NM_017946
FKBP14	hsa-miR-3163	96.4446	NM_017946
FKBP14	hsa-miR-338-5p	95.3864	NM_017946
FKBP14	hsa-miR-548c-3p	94.6308	NM_017946
FKBP14	hsa-miR-150-5p	94.3285	NM_017946
FKBP14	hsa-miR-4531	94.1542	NM_017946
FKBP14	hsa-miR-651-3p	90.4753	NM_017946
FKBP14	hsa-miR-6879-3p	89.9766	NM_017946
FKBP14	hsa-miR-7151-3p	89.1859	NM_017946
FKBP14	hsa-miR-4524a-3p	88.4624	NM_017946
FKBP14	hsa-miR-568	87.9418	NM_017946
FKBP14	hsa-miR-5580-3p	87.513	NM_017946
FKBP14	hsa-miR-7844-5p	87.383	NM_017946
FKBP14	hsa-miR-1277-5p	87.0784	NM_017946
FKBP14	hsa-miR-4301	86.089	NM_017946
FKBP14	hsa-miR-6835-5p	84.7374	NM_017946
FKBP14	hsa-miR-4528	83.4084	NM_017946
FKBP14	hsa-miR-361-5p	80.9893	NM_017946
FKBP14	hsa-miR-548ao-5p	80.9531	NM_017946
FKBP14	hsa-miR-548ax	80.9531	NM_017946
FKBP14	hsa-miR-432-5p	80.5744	NM_017946
FKBP14	hsa-miR-520d-5p	80.1086	NM_017946
FKBP14	hsa-miR-524-5p	80.1086	NM_017946

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Motifs and transcription factors (TFs) regulating FKBP14

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."